Publications by authors named "Midori A Arai"

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Heasquinazolinone, a New Heat-Shock Metabolite Produced by Thermotolerant Streptomyces sp. HR41.
Shun Saito, Risa Hagihara, Midori A Arai

Chem Pharm Bull (Tokyo)· October 2025

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Host-Pathogen Interaction Activated Biosynthesis of Natural Products.
Yukiko Ujie, Shun Saito, Chisato Iwata, Ruri Kuwahara, Shinji Kishimoto, Midori A Arai

J Nat Prod· September 2025

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The Heat-Shock Metabolite Streptolactam D, Produced by High-Temperature Culture of sp. JA74, Promotes Thermotolerance via Self-Membrane Stabilization.
Shun Saito, Yurika Okumura, Sosuke Kataoka, Keisuke Fukaya, Daisuke Urabe, Midori A Arai

J Am Chem Soc· May 2025

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Co-culture of Aspergillus niger IFM 59706 and RAW264 cells enhances the production of aurasperone A with nitric oxide inhibitory activity.
Yukiko Ujie, Shun Saito, Tomoya Banno, Takashi Yaguchi, Midori A Arai

Biosci Biotechnol Biochem· March 2025

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Aspergillus terreus IFM 65899-THP-1 cells interaction triggers production of the natural product butyrolactone Ia, an immune suppressive compound.
Yukiko Ujie, Shun Saito, Keisuke Fukaya, Daisuke Urabe, Takashi Yaguchi, Midori A Arai

Sci Rep· November 2024

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Activation of Secondary Metabolism and Protease Activity Mechanisms in the Black Koji Mold through Coculture with Animal Cells.
Yuri Asano, Shun Saito, Yukiko Ujie, Chisato Iwata, Takashi Yaguchi, Midori A Arai

ACS Omega· October 2024

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Methodology for awakening the potential secondary metabolic capacity in actinomycetes.
Shun Saito, Midori A Arai

Beilstein J Org Chem· April 2024

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3-Hydroxy-3-(2-oxopropyl)indolin-2-one, a product of a human-derived Enterocloster strain, is an inhibitor of nitric oxide production.
Shun Saito, Tomoya Banno, Midori A Arai

Biosci Biotechnol Biochem· February 2024

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Notch activator cyclopiazonic acid induces apoptosis in HL-60 cells through calcineurin activation.
Shiina Suzuki, Shun Saito, Yuki Narushima, Shunta Kodani, Noritaka Kagaya, Midori A Arai

J Antibiot (Tokyo)· January 2024

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Natural Compounds with BMI1 Promoter Inhibitory Activity from Mammea siamensis and Andrographis paniculata.
Kazuki Fujii, Yasumasa Hara, Midori A Arai, Samir K Sadhu, Firoj Ahmed

Chem Pharm Bull (Tokyo)· August 2023

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Dihydromaniwamycin E, a Heat-Shock Metabolite from Thermotolerant sp. JA74, Exhibiting Antiviral Activity against Influenza and SARS-CoV-2 Viruses.
Shun Saito, Kayo Funayama, Wataru Kato, Mayu Okuda, Meiko Kawamoto, Midori A Arai

J Nat Prod· November 2022

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Noaoxazole, a new heat shock metabolite produced by thermotolerant Streptomyces sp. HR41.
Shun Saito, Shiina Suzuki, Midori A Arai

J Antibiot (Tokyo)· September 2022

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Corrrection to "Two Bioactive Compounds, Uniformides A and B, Isolated from a Culture of IFM0856 in the Presence of Animal Cells".
Yasumasa Hara, Keiichiro Watanabe, Akiko Takaya, Itsuki Ebihara, Teruhisa Manome, Midori A Arai

Org Lett· August 2022

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Identification of 1β,2α-epoxytagitinin C as a Notch inhibitor, oxidative stress mechanism and its anti-leukemia activity.
Yoshinori Makita, Shun Saito, Anna Tsuchiya, Masami Ishibashi, Midori A Arai

J Nat Med· January 2022

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Evaluation of Naturally Occurring HIF-1 Inhibitors for Pulmonary Arterial Hypertension.
Midori A Arai, Kota Sakuraba, Yoshinori Makita, Yasumasa Hara, Masami Ishibashi

Chembiochem· September 2021

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Target Protein-Oriented Isolations for Bioactive Natural Products.
Midori A Arai

Chem Pharm Bull (Tokyo)· August 2021

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Isolation of nocobactin NAs as Notch signal inhibitors from Nocardia farcinica, a possibility of invasive evolution.
Midori A Arai, Itsuki Ebihara, Yoshinori Makita, Yasumasa Hara, Takashi Yaguchi

J Antibiot (Tokyo)· April 2021

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Acacienone, a terpenoid-like natural product having an unprecedented C20 framework isolated from Acacia mangium leaves.
Yasumasa Hara, Yuichi Totsugi, Hiroshi Ichikawa, Shinji Harada, Kazuki Fujii, Midori A Arai

J Nat Med· January 2021

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Total synthesis of lindbladione, a Hes1 dimerization inhibitor and neural stem cell activator isolated from Lindbladia tubulina.
Midori A Arai, Yuna Makita, Yumi Yamaguchi, Haruka Kawano, Akiko Suganami

Sci Rep· December 2020

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Isolation and evaluation of cardenolides from Lansium domesticum as Notch inhibitors.
Anna Tsuchiya, Yoshinori Makita, Takashi Koyano, Thaworn Kowithayakorn, Masami Ishibashi, Midori A Arai

J Nat Med· September 2020

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Cadinane sesquiterpenoids isolated from Santalum album using a screening program for Wnt signal inhibitory activity.
Tomoyuki Sato, Midori A Arai, Yixizhuoma, Yasumasa Hara, Takashi Koyano

J Nat Med· March 2020

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Target protein-oriented isolation of Hes1 dimer inhibitors using protein based methods.
Midori A Arai, Kaori Morita, Haruka Kawano, Yuna Makita, Manami Hashimoto

Sci Rep· January 2020

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Identification of BMI1 promoter inhibitors from Streptomyces sp. IFM-11958.
Yusuke Yokoyama, Midori A Arai, Yasumasa Hara, Masami Ishibashi

Bioorg Med Chem· July 2019

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Isolation of Nabscessin C from Nocardia abscessus IFM 10029 and a Study on Biosynthetic Pathway for Nabscessins.
Shoko Hara, Yasumasa Hara, Midori A Arai, Yoko Kusuya, Hiroki Takahashi

Chem Pharm Bull (Tokyo)· October 2018

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GLI1 Inhibitors Identified by Target Protein Oriented Natural Products Isolation (TPO-NAPI) with Hedgehog Inhibition.
Midori A Arai, Fumie Ochi, Yoshinori Makita, Tetsuhiro Chiba, Kyohei Higashi

ACS Chem Biol· September 2018

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