Publications by authors named "Mike Clements"

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Novel method for action potential measurements from intact cardiac monolayers with multiwell microelectrode array technology.
Heather B Hayes, Anthony M Nicolini, Colin A Arrowood, Stacie A Chvatal, David W Wolfson, Mike Clements

Sci Rep· August 2019

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Cross-Site Reliability of Human Induced Pluripotent stem cell-derived Cardiomyocyte Based Safety Assays Using Microelectrode Arrays: Results from a Blinded CiPA Pilot Study.
Daniel Millard, Qianyu Dang, Hong Shi, Xiaou Zhang, Chris Strock, Mike Clements

Toxicol Sci· August 2018

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The prospective IQ-CSRC trial: A prototype early clinical proarrhythmia assessment investigation for replacing the ICH E14 thorough QTc (TQT) study.
Icilio Cavero, Henry Holzgrefe, Mike Clements

J Pharmacol Toxicol Methods· May 2017

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Comprehensive in vitro Proarrhythmia Assay (CiPA): Pending issues for successful validation and implementation.
Icilio Cavero, Jean-Michel Guillon, Veronique Ballet, Mike Clements, Jean-Frédéric Gerbeau

J Pharmacol Toxicol Methods· May 2017

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Multielectrode Array (MEA) Assay for Profiling Electrophysiological Drug Effects in Human Stem Cell-Derived Cardiomyocytes.
Mike Clements

Curr Protoc Toxicol· May 2016

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Bridging Functional and Structural Cardiotoxicity Assays Using Human Embryonic Stem Cell-Derived Cardiomyocytes for a More Comprehensive Risk Assessment.
Mike Clements, Val Millar, Angela S Williams, Sian Kalinka

Toxicol Sci· November 2015

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High-throughput multi-parameter profiling of electrophysiological drug effects in human embryonic stem cell derived cardiomyocytes using multi-electrode arrays.
Mike Clements, Nick Thomas

Toxicol Sci· August 2014

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