Publications by authors named "Mike Helms"

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Trivalent siRNA-Conjugates with Guanosine as ASGPR-Binder Show Potent Knock-Down In Vivo.
Armin Hofmeister, Kerstin Jahn-Hofmann, Bodo Brunner, Mike Helms, Christiane Metz-Weidmann

J Med Chem· March 2025

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Small Interfering RNAs Containing Dioxane- and Morpholino-Derived Nucleotide Analogues Show Improved Off-Target Profiles and Chirality-Dependent Knock-Down.
Armin Hofmeister, Kerstin Jahn-Hofmann, Bodo Brunner, Mike Helms, Christiane Metz-Weidmann

J Med Chem· October 2022

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Syntheses of Morpholine-Based Nucleotide Analogs for Hepatic siRNA Targeting and Stabilization.
Armin Hofmeister, Kerstin Jahn-Hofmann, Bodo Brunner, Mike W Helms, Christiane Metz-Weidmann

J Med Chem· May 2021

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Nanobody-siRNA Conjugates for Targeted Delivery of siRNA to Cancer Cells.
Oleksandr Zavoiura, Bodo Brunner, Peter Casteels, Luciana Zimmermann, Matthias Ozog, Mike W Helms

Mol Pharm· March 2021

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Triantennary GalNAc Molecular Imaging Probes for Monitoring Hepatocyte Function in a Rat Model of Nonalcoholic Steatohepatitis.
Anurag Mishra, Tamara R Castañeda, Erik Bader, Bettina Elshorst, Sheila Cummings, Mike Helms

Adv Sci (Weinh)· December 2020

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Engagement of community stakeholders to develop a framework to guide research dissemination to communities.
Jennifer Cunningham-Erves, Tilicia Mayo-Gamble, Yolanda Vaughn, Jim Hawk, Mike Helms

Health Expect· August 2020

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Utility of the RIG-I Agonist Triphosphate RNA for Melanoma Therapy.
Mike W Helms, Kerstin Jahn-Hofmann, Felix Gnerlich, Christiane Metz-Weidmann, Monika Braun

Mol Cancer Ther· December 2019

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Oncogenic dependency on β-catenin in liver cancer cell lines correlates with pathway activation.
Zhihu Ding, Chaomei Shi, Lan Jiang, Tatiana Tolstykh, Hui Cao, Mike W Helms

Oncotarget· December 2017

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Epigenetic and Transcriptional Regulation of IRAK-M Expression in Macrophages.
Konstantina Lyroni, Andreas Patsalos, Maria G Daskalaki, Christina Doxaki, Birte Soennichsen, Mike Helms

J Immunol· February 2017

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Akt2 deficiency protects from acute lung injury via alternative macrophage activation and miR-146a induction in mice.
Eleni Vergadi, Katerina Vaporidi, Emmanuel E Theodorakis, Christina Doxaki, Eleni Lagoudaki, Mike Helms

J Immunol· January 2014

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Image-guided genomic analysis of tissue response to laser-induced thermal stress.
Mark A Mackanos, Mike Helms, Flora Kalish, Christopher H Contag

J Biomed Opt· May 2011

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IL-12 enhances efficacy and shortens enrichment time in cytokine-induced killer cell immunotherapy.
Mike W Helms, Jennifer A Prescher, Yu-An Cao, Steven Schaffert, Christopher H Contag

Cancer Immunol Immunother· September 2010

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TOB1 is regulated by EGF-dependent HER2 and EGFR signaling, is highly phosphorylated, and indicates poor prognosis in node-negative breast cancer.
Mike W Helms, Dirk Kemming, Christopher H Contag, Heike Pospisil, Kai Bartkowiak

Cancer Res· June 2009

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Quantifying cell-surface biomarker expression in thick tissues with ratiometric three-dimensional microscopy.
Jonathan T C Liu, Mike W Helms, Michael J Mandella, James M Crawford, Gordon S Kino

Biophys J· March 2009

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Options for visualizing metastatic disease in the living body.
Mike W Helms, Burkhard H Brandt, Christopher H Contag

Contrib Microbiol· July 2006

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First evidence supporting a potential role for the BMP/SMAD pathway in the progression of oestrogen receptor-positive breast cancer.
Mike W Helms, Jens Packeisen, Christian August, Birgit Schittek, Werner Boecker

J Pathol· July 2005

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Activation mechanism of pro-astacin: role of the pro-peptide, tryptic and autoproteolytic cleavage and importance of precise amino-terminal processing.
Irene Yiallouros, Reinhild Kappelhoff, Oliver Schilling, Frank Wegmann, Mike W Helms

J Mol Biol· November 2002

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