Publications by authors named "Mikhail Akimov"

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Two-Step Cell Death Induction by the New 2-Arachidonoyl Glycerol Analog and Its Modulation by Lysophosphatidylinositol in Human Breast Cancer Cells.
Mikhail G Akimov, Natalia M Gretskaya, Evgenia I Gorbacheva, Nisreen Khadour, Galina D Sherstyanykh

Int J Mol Sci· January 2025

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Anti-Proliferative Activity of Ethylenediurea Derivatives with Alkyl and Oxygen-Containing Groups as Substituents.
Maxim Oshchepkov, Leonid Kovalenko, Antonida Kalistratova, Galina Sherstyanykh, Evgenia Gorbacheva, Mikhail Akimov

Biomedicines· January 2025

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The Interaction of the Endocannabinoid Anandamide and Paracannabinoid Lysophosphatidylinositol during Cell Death Induction in Human Breast Cancer Cells.
Mikhail G Akimov, Natalia M Gretskaya, Evgenia I Gorbacheva, Nisreen Khadour, Valeria S Chernavskaya

Int J Mol Sci· February 2024

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Co-delivery of paclitaxel and etoposide prodrug by human serum albumin and PLGA nanoparticles: synergistic cytotoxicity in brain tumour cells.
Tatyana Kovshova, Sergey Mantrov, Svetlana Boiko, Julia Malinovskaya, Maria Merkulova, Mikhail Akimov

J Microencapsul· June 2023

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Multicomponent Lipid Nanoparticles for RNA Transfection.
Nataliya Gretskaya, Mikhail Akimov, Dmitry Andreev, Anton Zalygin, Ekaterina Belitskaya

Pharmaceutics· April 2023

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The Mechanisms of GPR55 Receptor Functional Selectivity during Apoptosis and Proliferation Regulation in Cancer Cells.
Mikhail G Akimov, Natalia M Gretskaya, Polina V Dudina, Galina D Sherstyanykh, Galina N Zinchenko

Int J Mol Sci· March 2023

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Anti-Proliferative and Cytoprotective Activity of Aryl Carbamate and Aryl Urea Derivatives with Alkyl Groups and Chlorine as Substituents.
Maxim Oshchepkov, Leonid Kovalenko, Antonida Kalistratova, Maria Ivanova, Galina Sherstyanykh, Mikhail Akimov

Molecules· June 2022

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-Acyl Dopamines Induce Apoptosis in Endometrial Stromal Cells from Patients with Endometriosis.
Alina M Gamisonia, Marina N Yushina, Irina A Fedorova-Gogolina, Mikhail G Akimov, Chupalav M Eldarov

Int J Mol Sci· September 2021

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N-arachidonoyl dopamine inhibits epithelial-mesenchymal transition of breast cancer cells through ERK signaling and decreasing the cellular cholesterol.
Shreetama Bandyopadhayaya, Mikhail G Akimov, Ranjeet Verma, Ankit Sharma, Divya Sharma

J Biochem Mol Toxicol· April 2021

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ACTH(6-9)PGP Peptide Protects SH-SY5Y Cells from HO, -Butyl Hydroperoxide, and Cyanide Cytotoxicity via Stimulation of Proliferation and Induction of Prosurvival-Related Genes.
Mikhail G Akimov, Elena V Fomina-Ageeva, Polina V Dudina, Ludmila A Andreeva, Nikolay F Myasoyedov

Molecules· March 2021

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5-alkylvinyl-1,2,4-triazole nucleosides: Synthesis and biological evaluation.
Alexander N Prutkov, Mikhail V Chudinov, Andrey V Matveev, Lyubov E Grebenkina, Mikhail G Akimov

Nucleosides Nucleotides Nucleic Acids· January 2021

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GPR55 Receptor Activation by the -Acyl Dopamine Family Lipids Induces Apoptosis in Cancer Cells via the Nitric Oxide Synthase (nNOS) Over-Stimulation.
Mikhail G Akimov, Alina M Gamisonia, Polina V Dudina, Natalia M Gretskaya, Anastasia A Gaydaryova

Int J Mol Sci· January 2021

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In Vivo Targeted Metabolomic Profiling of Prostanit, a Novel Anti-PAD NO-Donating Alprostadil-Based Drug.
Ksenia M Shestakova, Natalia E Moskaleva, Natalia V Mesonzhnik, Alexey V Kukharenko, Igor V Serkov, Mikhail G Akimov

Molecules· December 2020

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Novel bexarotene derivatives: Synthesis and cytotoxicity evaluation for glioma cells in 2D and 3D in vitro models.
Natalia M Gretskaya, Alina M Gamisonia, Polina V Dudina, Stanislav S Zakharov, Galina Sherstyanykh, Mikhail G Akimov

Eur J Pharmacol· September 2020

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Capmatinib in Exon 14-Mutated or -Amplified Non-Small-Cell Lung Cancer.
Jürgen Wolf, Takashi Seto, Ji-Youn Han, Noemi Reguart, Edward B Garon, Mikhail Akimov

N Engl J Med· September 2020

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Phase 1 study of capmatinib in MET-positive solid tumor patients: Dose escalation and expansion of selected cohorts.
Yung-Jue Bang, Wu-Chou Su, Martin Schuler, Do-Hyun Nam, Wan Teck Lim, Mikhail Akimov

Cancer Sci· February 2020

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Arachidonoylcholine and Other Unsaturated Long-Chain Acylcholines Are Endogenous Modulators of the Acetylcholine Signaling System.
Mikhail G Akimov, Denis S Kudryavtsev, Elena V Kryukova, Elena V Fomina-Ageeva, Stanislav S Zakharov

Biomolecules· February 2020

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Phase Ib/II Study of Capmatinib (INC280) Plus Gefitinib After Failure of Epidermal Growth Factor Receptor (EGFR) Inhibitor Therapy in Patients With EGFR-Mutated, MET Factor-Dysregulated Non-Small-Cell Lung Cancer.
Yi-Long Wu, Li Zhang, Dong-Wan Kim, Xiaoqing Liu, Dae Ho Lee, Mikhail Akimov

J Clin Oncol· November 2018

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Phase 2 Study of the HSP-90 Inhibitor AUY922 in Previously Treated and Molecularly Defined Patients with Advanced Non-Small Cell Lung Cancer.
Enriqueta Felip, Fabrice Barlesi, Benjamin Besse, Quincy Chu, Leena Gandhi, Mikhail Akimov

J Thorac Oncol· April 2018

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Ocular toxicity of AUY922 in pigmented and albino rats.
Danielle Roman, James VerHoeve, Heiko Schadt, Axel Vicart, Ursula Junker Walker, Mikhail Akimov

Toxicol Appl Pharmacol· October 2016

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Phase 1B/2 study of the HSP90 inhibitor AUY922 plus trastuzumab in metastatic HER2-positive breast cancer patients who have progressed on trastuzumab-based regimen.
Anthony Kong, Daniel Rea, Samreen Ahmed, J Thaddeus Beck, Rafael López López, Mikhail Akimov

Oncotarget· June 2016

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Activation of MET via diverse exon 14 splicing alterations occurs in multiple tumor types and confers clinical sensitivity to MET inhibitors.
Garrett M Frampton, Siraj M Ali, Mark Rosenzweig, Juliann Chmielecki, Xinyuan Lu, Mikhail Akimov

Cancer Discov· August 2015

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Phase 1/1B trial of the heat shock protein 90 inhibitor NVP-AUY922 as monotherapy or in combination with bortezomib in patients with relapsed or refractory multiple myeloma.
Ruth Seggewiss-Bernhardt, Ralf C Bargou, Yeow Tee Goh, A Keith Stewart, Andrew Spencer, Mikhail Akimov

Cancer· July 2015

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Cytotoxicity of Endogenous Lipids N-acyl Dopamines and their Possible Metabolic Derivatives for Human Cancer Cell Lines of Different Histological Origin.
Mikhail G Akimov, Natalia M Gretskaya, Galina N Zinchenko, Vladimir V Bezuglov

Anticancer Res· May 2015

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89Zr-trastuzumab and 89Zr-bevacizumab PET to evaluate the effect of the HSP90 inhibitor NVP-AUY922 in metastatic breast cancer patients.
Sietske B M Gaykema, Carolien P Schröder, Joanna Vitfell-Rasmussen, Sue Chua, Thijs H Oude Munnink, Mikhail Akimov

Clin Cancer Res· August 2014

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