Publications by authors named "Milad Botros"

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Interconversion of Functional Activity by Minor Structural Alterations in Nonpeptide AT2 Receptor Ligands.
Charlotta Wallinder, Christian Sköld, Milad Botros, Marie-Odile Guimond, Mathias Hallberg

ACS Med Chem Lett· February 2015

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From the first selective non-peptide AT(2) receptor agonist to structurally related antagonists.
A M S Murugaiah, Xiongyu Wu, Charlotta Wallinder, A K Mahalingam, Yiqian Wan, Milad Botros

J Med Chem· March 2012

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Selective angiotensin II AT(2) receptor agonists with reduced CYP 450 inhibition.
A K Mahalingam, Yiqian Wan, A M S Murugaiah, Charlotta Wallinder, Xiongyu Wu, Milad Botros

Bioorg Med Chem· June 2010

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Discovery of dipeptides with high affinity to the specific binding site for substance P1-7.
Rebecca Fransson, Milad Botros, Christian Sköld, Fred Nyberg, Gunnar Lindeberg

J Med Chem· March 2010

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The C-terminal amidated analogue of the substance P (SP) fragment SP(1-7) attenuates the expression of naloxone-precipitated withdrawal in morphine dependent rats.
Qin Zhou, Anna Carlsson, Milad Botros, Rebecca Fransson, Anja Sandström

Peptides· December 2009

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Endomorphins interact with the substance P (SP) aminoterminal SP(1-7) binding in the ventral tegmental area of the rat brain.
Milad Botros, Tobias Johansson, Qin Zhou, Gunnar Lindeberg, Csaba Tömböly

Peptides· October 2008

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Selective angiotensin II AT2 receptor agonists: Benzamide structure-activity relationships.
Charlotta Wallinder, Milad Botros, Ulrika Rosenström, Marie-Odile Guimond, Hélène Beaudry

Bioorg Med Chem· July 2008

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Small peptides mimicking substance P (1-7) and encompassing a C-terminal amide functionality.
Rebecca Fransson, Milad Botros, Fred Nyberg, Gunnar Lindeberg, Anja Sandström

Neuropeptides· February 2008

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Selective angiotensin II AT(2) receptor agonists devoid of the imidazole ring system.
A M S Murugaiah, Chalotta Wallinder, A K Mahalingam, Xiongyu Wu, Yiqian Wan, Milad Botros

Bioorg Med Chem· November 2007

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Synthesis of a new class of druglike angiotensin II C-terminal mimics with affinity for the AT2 receptor.
Jennie Georgsson, Christian Sköld, Milad Botros, Gunnar Lindeberg, Fred Nyberg

J Med Chem· April 2007

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Selective angiotensin II AT2 receptor agonists: arylbenzylimidazole structure-activity relationships.
Xiongyu Wu, Yiqian Wan, A K Mahalingam, A M S Murugaiah, Bianca Plouffe, Milad Botros

J Med Chem· November 2006

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Design, synthesis, and incorporation of a beta-turn mimetic in angiotensin II forming novel pseudopeptides with affinity for AT1 and AT2 receptors.
Ulrika Rosenström, Christian Sköld, Gunnar Lindeberg, Milad Botros, Fred Nyberg

J Med Chem· October 2006

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Short pseudopeptides containing turn scaffolds with high AT2 receptor affinity.
Jennie Georgsson, Ulrika Rosenström, Charlotta Wallinder, Hélène Beaudry, Bianca Plouffe, Milad Botros

Bioorg Med Chem· September 2006

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Endomorphin-1 and endomorphin-2 differentially interact with specific binding sites for substance P (SP) aminoterminal SP1-7 in the rat spinal cord.
Milad Botros, Mathias Hallberg, Tobias Johansson, Qin Zhou, Gunnar Lindeberg

Peptides· April 2006

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Angiotensin II pseudopeptides containing 1,3,5-trisubstituted benzene scaffolds with high AT2 receptor affinity.
Jennie Georgsson, Christian Sköld, Bianca Plouffe, Gunnar Lindeberg, Milad Botros

J Med Chem· October 2005

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New selective AT2 receptor ligands encompassing a gamma-turn mimetic replacing the amino acid residues 4-5 of angiotensin II act as agonists.
Ulrika Rosenström, Christian Sköld, Bianca Plouffe, Hélène Beaudry, Gunnar Lindeberg, Milad Botros

J Med Chem· June 2005

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First reported nonpeptide AT1 receptor agonist (L-162,313) acts as an AT2 receptor agonist in vivo.
Yiqian Wan, Charlotta Wallinder, Berndt Johansson, Mathias Holm, A K Mahalingam, Milad Botros

J Med Chem· March 2004

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A selective AT2 receptor ligand with a gamma-turn-like mimetic replacing the amino acid residues 4-5 of angiotensin II.
Ulrika Rosenström, Christian Sköld, Gunnar Lindeberg, Milad Botros, Fred Nyberg

J Med Chem· February 2004

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