Publications by authors named "Ming-Ching Hsieh"

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Enhanced ADCC Activity of a C-Terminal Lysine Variant of an IgG Antibody Driven by N-Linked MAN5 Glycan Using a Reporter Gene Assay.
Ming-Ching Hsieh, Kristiina Dorofejeva, Jingming Zhang, Diane L Vy, Jun Qian

Antibodies (Basel)· October 2025

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Characterization of the Charge Heterogeneity of a Monoclonal Antibody That Binds to Both Cation Exchange and Anion Exchange Columns under the Same Binding Conditions.
Ming-Ching Hsieh, Jingming Zhang, Liangjie Tang, Cheng-Yen Huang, Yang Shen

Antibodies (Basel)· June 2024

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Effect of Peroxide- Versus Alkoxyl-Induced Chemical Oxidation on the Structure, Stability, Aggregation, and Function of a Therapeutic Monoclonal Antibody.
Dinen D Shah, Jingming Zhang, Ming-Ching Hsieh, Shanmuuga Sundaram, Haripada Maity

J Pharm Sci· November 2018

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Effect of Surfactants on Mechanical, Thermal, and Photostability of a Monoclonal Antibody.
Meera Agarkhed, Courtney O'Dell, Ming-Ching Hsieh, Jingming Zhang, Joel Goldstein

AAPS PharmSciTech· January 2018

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Application of Tryptophan Fluorescence Bandwidth-Maximum Plot in Analysis of Monoclonal Antibody Structure.
Cheng-Yen Huang, Ming-Ching Hsieh, Qinwei Zhou

AAPS PharmSciTech· April 2017

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Conformational characterization of the charge variants of a human IgG1 monoclonal antibody using H/D exchange mass spectrometry.
Liangjie Tang, Shanmuuga Sundaram, Jingming Zhang, Ping Carlson, Alice Matathia, Ming-Ching Hsieh

MAbs· July 2013

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Effect of polysorbate 80 concentration on thermal and photostability of a monoclonal antibody.
Meera Agarkhed, Courtney O'Dell, Ming-Ching Hsieh, Jingming Zhang, Joel Goldstein

AAPS PharmSciTech· March 2013

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An innovative approach for the characterization of the isoforms of a monoclonal antibody product.
Shanmuuga Sundaram, Alice Matathia, Jun Qian, Jingming Zhang, Ming-Ching Hsieh

MAbs· June 2012

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Effect of polysorbate 80 quality on photostability of a monoclonal antibody.
Swita R Singh, Jingming Zhang, Courtney O'Dell, Ming-Ching Hsieh, Joel Goldstein

AAPS PharmSciTech· June 2012

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Structure-function engineering of interferon-beta-1b for improving stability, solubility, potency, immunogenicity, and pharmacokinetic properties by site-selective mono-PEGylation.
Amartya Basu, Karen Yang, Maoliang Wang, Sam Liu, Ramesh Chintala, Ming-Ching Hsieh

Bioconjug Chem· July 2006

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Tailoring structure-function and pharmacokinetic properties of single-chain Fv proteins by site-specific PEGylation.
Karen Yang, Amartya Basu, Maoliang Wang, Ramesh Chintala, Ming-Ching Hsieh

Protein Eng· October 2003

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Inhibition of prostate-specific antigen (PSA) by alpha(1)-antichymotrypsin: salt-dependent activation mediated by a conformational change.
Ming-Ching Hsieh, Barry S Cooperman

Biochemistry· March 2002

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