Publications by authors named "Minlu Cheng"

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Clinical pharmacokinetics and immunogenicity evaluation of a trophoblast cell surface antigen 2-targeted antibody-drug conjugate, FDA018, in patients with epithelial malignant solid tumors.
Minlu Cheng, Xianjing Li, Ya Li, Yiya Wang, Wenjia Li

Drug Metab Dispos· November 2025

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LBA and LC-MS/MS based comprehensive bioanalytical methods for FDA018, a Trop-2 targeted antibody-drug conjugate.
Minlu Cheng, Xianjing Li, Ya Li, Yiya Wang, Wenjia Li

J Pharm Biomed Anal· October 2025

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Development and validation of an LC-MS/MS method for quantifying a new G protein selective μ-opioid receptor agonist YZJ-4729 and its major metabolite M10 in human plasma to support a phase I study in healthy subjects.
Yufeng Ni, Chenxin Ding, Minlu Cheng, Li Ding

J Chromatogr B Analyt Technol Biomed Life Sci· September 2025

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Drug interaction evaluation of the novel phosphodiesterase type 5 inhibitor tunodafil (youkenafil): Effects of tunodafil on omeprazole pharmacokinetics based on CYP2C19 gene polymorphism, and effects of ritonavir on tunodafil pharmacokinetics.
Keli Wang, Juefang Ding, Minlu Cheng, Xianjing Li, Huan Zhou

Eur J Pharm Sci· March 2025

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LC-MS/MS method for dual-ligand peptide-drug CBP-1018 and its deconjugated payload MMAE including sample stabilization strategy for its MC-Val-Cit-PABC linker.
Xianjing Li, Minlu Cheng, Yiya Wang, Chang Shu, Bingjie Zou

Talanta· November 2024

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Pharmacokinetics, metabolite profiling, safety and tolerability of YZJ-4729 tartrate, a novel G protein-biased μ-opioid receptor agonist, in healthy Chinese subjects.
Yufeng Ni, Huaye Gao, Wen Ouyang, Guoping Yang, Minlu Cheng

Front Pharmacol· January 2024

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The metabolite profiling of YR-1702 injection in human plasma, urine and feces by HPLC-Q-TOF-MS/MS.
Yuxuan Fan, Yufeng Ni, Minlu Cheng, Wenjing Guo, Huaye Gao

Xenobiotica· December 2023

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Development and validation of LC-MS/MS methods for the quantification of 101BHG-D01, a novel, long-acting and selective muscarinic receptor antagonist, and its main metabolite M6 in human plasma, urine and feces: Application to a clinical study in healthy Chinese subjects.
Huaye Gao, Minlu Cheng, Haijun Liu, Li Ding

J Pharm Biomed Anal· September 2023

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Pharmacokinetics, metabolite profiling, safety, and tolerability of inhalation aerosol of 101BHG-D01, a novel, long-acting and selective muscarinic receptor antagonist, in healthy Chinese subjects.
Huaye Gao, Jintong Li, Xiaoping Chen, Zhanguo Sun, Gang Cui, Minlu Cheng

Front Pharmacol· December 2022

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Development and validation of a highly sensitive and selective LC-MS/MS method for the determination of 15-hydroxylubiprostone in human plasma: application to a pharmacokinetic study in healthy Chinese volunteers.
Xianjing Li, Haitao Yu, Wenjing Guo, Minlu Cheng, Qinxin Song

Xenobiotica· June 2022

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Simultaneous quantification of chlorogenic acid and taurocholic acid in human plasma by LC-MS/MS and its application to a pharmacokinetic study after oral administration of Shuanghua Baihe tablets.
Pan Gu, Rui-Juan Liu, Min-Lu Cheng, Yao Wu, Lu Zheng, Peng-Cheng Ma

Chin J Nat Med· April 2016

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Simultaneous determination of corynoline and acetylcorynoline in human urine by LC-MS/MS and its application to a urinary excretion study.
Ruijuan Liu, Lu Zheng, Minlu Cheng, Yao Wu, Pan Gu, Pengcheng Ma

J Chromatogr B Analyt Technol Biomed Life Sci· March 2016

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Study on the pharmacokinetic profiles of corynoline and its potential interaction in traditional Chinese medicine formula Shuanghua Baihe tablets in rats by LC-MS/MS.
Ruijuan Liu, Pan Gu, Lei Wang, Minlu Cheng, Yao Wu

J Pharm Biomed Anal· January 2016

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LC-MS/MS determination and urinary excretion study of seven alkaloids in healthy Chinese volunteers after oral administration of Shuanghua Baihe tablets.
Minlu Cheng, Ruijuan Liu, Yao Wu, Pan Gu, Lu Zheng, Pengcheng Ma

J Pharm Biomed Anal· January 2016

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Highly sensitive method for simultaneous determination of nine alkaloids of Shuanghua Baihe tablets in human plasma by LC-MS/MS and its application.
Yao Wu, Ruijuan Liu, Pan Gu, Minlu Cheng, Lu Zheng, Pengcheng Ma

J Chromatogr B Analyt Technol Biomed Life Sci· December 2015

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Pharmacokinetics of propafenone hydrochloride sustained-release capsules in male beagle dogs.
Liping Pan, Yafang Qian, Minlu Cheng, Pan Gu, Yanna He

Acta Pharm Sin B· January 2015

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