Publications by authors named "Miranda Lau"

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High-throughput screening identifies a novel small-molecule modulator of Hsp70 that selectively enhances ubiquitination and degradation of misfolded neuronal NO synthase.
Anthony M Garcia, Amanda K Davis, Cristian Martinez-Ramos, Yoshihiro Morishima, Miranda Lau

Mol Pharmacol· February 2025

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Mapping interactions of calmodulin and neuronal NO synthase by crosslinking and mass spectrometry.
Dana Felker, Kanghyun Lee, Thomas H Pospiech, Yoshihiro Morishima, Haoming Zhang, Miranda Lau

J Biol Chem· January 2024

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Dynamic cycling with a unique Hsp90/Hsp70-dependent chaperone machinery and GAPDH is needed for heme insertion and activation of neuronal NO synthase.
Yoshihiro Morishima, Miranda Lau, William B Pratt, Yoichi Osawa

J Biol Chem· February 2023

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Mapping protein-protein interactions in homodimeric CYP102A1 by crosslinking and mass spectrometry.
Dana Felker, Haoming Zhang, Zhiyuan Bo, Miranda Lau, Yoshihiro Morishima

Biophys Chem· July 2021

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Hsp70:CHIP Ubiquitinates Dysfunctional but Not Native Neuronal NO Synthase.
Amanda K Davis, Natalie F McMyn, Miranda Lau, Yoshihiro Morishima, Yoichi Osawa

Mol Pharmacol· September 2020

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Chaperone Activity and Dimerization Properties of Hsp90 and Hsp90 in Glucocorticoid Receptor Activation by the Multiprotein Hsp90/Hsp70-Dependent Chaperone Machinery.
Yoshihiro Morishima, Ranjit K Mehta, Miyako Yoshimura, Miranda Lau, Daniel R Southworth

Mol Pharmacol· September 2018

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Improved method for assembly of hemeprotein neuronal NO-synthase heterodimers.
Yoshihiro Morishima, Haoming Zhang, Miranda Lau, Yoichi Osawa

Anal Biochem· October 2016

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Architecture of the nitric-oxide synthase holoenzyme reveals large conformational changes and a calmodulin-driven release of the FMN domain.
Adam L Yokom, Yoshihiro Morishima, Miranda Lau, Min Su, Alisa Glukhova

J Biol Chem· June 2014

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Heme-dependent activation of neuronal nitric oxide synthase by cytosol is due to an Hsp70-dependent, thioredoxin-mediated thiol-disulfide interchange in the heme/substrate binding cleft.
Yoshihiro Morishima, Miranda Lau, Hwei-Ming Peng, Yoshinari Miyata, Jason E Gestwicki

Biochemistry· August 2011

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Naturally occurring neuronal NO-synthase inactivators found in Nicotiana tabacum (Solanaceae) and other plants.
Ezra R Lowe, Andrew C Everett, Miranda Lau, Anwar Y Dunbar, David Michener

Phytomedicine· May 2007

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Plant-Derived Small Molecule Inhibitors of Neuronal NO-Synthase: Potential Effects on Protein Degradation.
Yoichi Osawa, Miranda Lau, Ezra R Lowe

Plant Signal Behav· March 2007

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Tetrahydrobiopterin protects against guanabenz-mediated inhibition of neuronal nitric-oxide synthase in vitro and in vivo.
Anwar Y Dunbar, Gary J Jenkins, Suree Jianmongkol, Mikiya Nakatsuka, Ezra R Lowe, Miranda Lau

Drug Metab Dispos· September 2006

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Tetrahydrobiopterin depletion and ubiquitylation of neuronal nitric oxide synthase.
Yasuhiko Kamada, Gary J Jenkins, Miranda Lau, Anwar Y Dunbar, Ezra R Lowe

Brain Res Mol Brain Res· December 2005

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Metabolism of aminoguanidine, diaminoguanidine, and NG-amino-L-arginine by neuronal NO-synthase and covalent alteration of the heme prosthetic group.
Anthony J Lee, Kathleen R Noon, Suree Jianmongkol, Miranda Lau, Gary J Jenkins

Chem Res Toxicol· December 2005

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Cti6 is an Rpd3-Sin3 histone deacetylase-associated protein required for growth under iron-limiting conditions in Saccharomyces cerevisiae.
Sergi Puig, Miranda Lau, Dennis J Thiele

J Biol Chem· July 2004

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Biochemical and genetic analyses of yeast and human high affinity copper transporters suggest a conserved mechanism for copper uptake.
Sergi Puig, Jaekwon Lee, Miranda Lau, Dennis J Thiele

J Biol Chem· July 2002

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