Publications by authors named "Mireille Sebbag"

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Bispecific nanobody® as a new pharmacological drug for the selective inhibition of Trypsin-3.
Melissa David, Anaïs Faihy, Corinne Rolland, Anissa Edir, Astrid Canivet, Mireille Sebbag

Br J Pharmacol· October 2025

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Chymotrypsin activity signals to intestinal epithelium by protease-activated receptor-dependent mechanisms.
Simon Guignard, Mahmoud Saifeddine, Koichiro Mihara, Majid Motahhary, Magali Savignac, Mireille Sebbag

Br J Pharmacol· August 2024

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Active thrombin produced by the intestinal epithelium controls mucosal biofilms.
Jean-Paul Motta, Alexandre Denadai-Souza, David Sagnat, Laura Guiraud, Anissa Edir, Mireille Sebbag

Nat Commun· July 2019

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Neutrophil extracellular traps exert both pro- and anti-inflammatory actions in rheumatoid arthritis that are modulated by C1q and LL-37.
Matthieu Ribon, Sarra Seninet, Julie Mussard, Mireille Sebbag, Cyril Clavel

J Autoimmun· March 2019

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Seropositivity and Antibody Profiling of Patients Are Dramatically Impacted by the Features of Peptides Used as Immunosorbents: A Lesson from Anti-Citrullinated Protein/Peptide Antibody.
Martin Cornillet, Fruzsina Babos, Anna Magyar, Mireille Sebbag, Evelyne Verrouil

J Immunol· December 2018

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Among human macrophages polarised to different phenotypes, the M-CSF-oriented cells present the highest pro-inflammatory response to the rheumatoid arthritis-specific immune complexes containing ACPA.
Cyril Clavel, Laurie Ceccato, Florence Anquetil, Guy Serre, Mireille Sebbag

Ann Rheum Dis· December 2016

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IgM rheumatoid factor amplifies the inflammatory response of macrophages induced by the rheumatoid arthritis-specific immune complexes containing anticitrullinated protein antibodies.
Lætitia Laurent, Florence Anquetil, Cyril Clavel, Ndiémé Ndongo-Thiam, Géraldine Offer, Mireille Sebbag

Ann Rheum Dis· July 2015

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IgM and IgA rheumatoid factors purified from rheumatoid arthritis sera boost the Fc receptor- and complement-dependent effector functions of the disease-specific anti-citrullinated protein autoantibodies.
Florence Anquetil, Cyril Clavel, Géraldine Offer, Guy Serre, Mireille Sebbag

J Immunol· April 2015

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Contact with stimulated T cells up-regulates expression of peptidylarginine deiminase 2 and 4 by human monocytes.
Sylvie Ferrari-Lacraz, Mireille Sebbag, Rachel Chicheportiche, Céline Foulquier, Guy Serre

Eur Cytokine Netw· June 2012

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The antigen specificity of the rheumatoid arthritis-associated ACPA directed to citrullinated fibrin is very closely restricted.
Cristina Iobagiu, Anna Magyar, Leonor Nogueira, Martin Cornillet, Mireille Sebbag

J Autoimmun· December 2011

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Deimination and expression of peptidylarginine deiminases during cutaneous wound healing in mice.
Fanny Coudane, Marie-Claire Mechin, Anne Huchenq, Julie Henry, Rachida Nachat, Mireille Sebbag

Eur J Dermatol· September 2011

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Fcγ receptor profile of monocytes and macrophages from rheumatoid arthritis patients and their response to immune complexes formed with autoantibodies to citrullinated proteins.
Lætitia Laurent, Cyril Clavel, Olivia Lemaire, Florence Anquetil, Martin Cornillet, Mireille Sebbag

Ann Rheum Dis· June 2011

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Induction of macrophage secretion of tumor necrosis factor alpha through Fcgamma receptor IIa engagement by rheumatoid arthritis-specific autoantibodies to citrullinated proteins complexed with fibrinogen.
Cyril Clavel, Leonor Nogueira, Laetitia Laurent, Cristina Iobagiu, Christian Vincent, Mireille Sebbag

Arthritis Rheum· March 2008

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Peptidyl arginine deiminase type 2 (PAD-2) and PAD-4 but not PAD-1, PAD-3, and PAD-6 are expressed in rheumatoid arthritis synovium in close association with tissue inflammation.
Céline Foulquier, Mireille Sebbag, Cyril Clavel, Sabine Chapuy-Regaud, Roula Al Badine

Arthritis Rheum· November 2007

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Epitopes of human fibrin recognized by the rheumatoid arthritis-specific autoantibodies to citrullinated proteins.
Mireille Sebbag, Nathalie Moinard, Isabelle Auger, Cyril Clavel, Jacques Arnaud

Eur J Immunol· August 2006

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Influence of HLA-DR genes on the production of rheumatoid arthritis-specific autoantibodies to citrullinated fibrinogen.
Isabelle Auger, Mireille Sebbag, Christian Vincent, Nathalie Balandraud, Sandrine Guis

Arthritis Rheum· November 2005

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Fibrin deimination in synovial tissue is not specific for rheumatoid arthritis but commonly occurs during synovitides.
Sabine Chapuy-Regaud, Mireille Sebbag, Dominique Baeten, Cyril Clavel, Céline Foulquier

J Immunol· April 2005

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Autoantibodies to citrullinated proteins: ACPA.
Christian Vincent, Leonor Nogueira, Cyril Clavel, Mireille Sebbag, Guy Serre

Autoimmunity· February 2005

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Clinical and pathophysiological significance of the autoimmune response to citrullinated proteins in rheumatoid arthritis.
Mireille Sebbag, Sabine Chapuy-Regaud, Isabelle Auger, Elisabeth Petit-Texeira, Cyril Clavel

Joint Bone Spine· November 2004

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cDNA cloning, gene organization and expression analysis of human peptidylarginine deiminase type I.
Marina Guerrin, Akihito Ishigami, Marie-Claire Méchin, Rachida Nachat, Séverine Valmary, Mireille Sebbag

Biochem J· February 2003

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Detection of antibodies to deiminated recombinant rat filaggrin by enzyme-linked immunosorbent assay: a highly effective test for the diagnosis of rheumatoid arthritis.
Christian Vincent, Leonor Nogueira, Mireille Sebbag, Sabine Chapuy-Regaud, Michel Arnaud

Arthritis Rheum· August 2002

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