Publications by authors named "Miro A Astore"

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The Inaugural Flatiron Institute Cryo-EM Conformational Heterogeneity Challenge.
Miro A Astore, Geoffrey Woollard, David Silva-Sánchez, Wenda Zhou, Mykhailo Kopylov

bioRxiv· November 2025

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cryoJAX: A Cryo-electron Microscopy Image Simulation Library In JAX.
Michael J O'Brien, David Silva-Sánchez, Geoffrey Woollard, Kwanghwi Je, Sonya M Hanson, Miro A Astore

bioRxiv· October 2025

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The ManifoldEM method for cryo-EM: a step-by-step breakdown accompanied by a modern Python implementation.
Anupam Anand Ojha, Robert Blackwell, Eduardo R Cruz-Chú, Raison Dsouza, Miro A Astore

Acta Crystallogr D Struct Biol· March 2025

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Protein dynamics underlying allosteric regulation.
Miro A Astore, Akshada S Pradhan, Erik H Thiede, Sonya M Hanson

Curr Opin Struct Biol· February 2024

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Mitochondrial electron transport chain, ceramide, and coenzyme Q are linked in a pathway that drives insulin resistance in skeletal muscle.
Alexis Diaz-Vegas, Søren Madsen, Kristen C Cooke, Luke Carroll, Jasmine X Y Khor, Miro A Astore

Elife· December 2023

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Mitochondrial electron transport chain, ceramide and Coenzyme Q are linked in a pathway that drives insulin resistance in skeletal muscle.
Alexis Diaz-Vegas, Soren Madsen, Kristen C Cooke, Luke Carroll, Jasmine X Y Khor, Miro A Astore

bioRxiv· September 2023

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Q1291H-CFTR molecular dynamics simulations and theratyping in nasal epithelial models and clinical response to elexacaftor/tezacaftor/ivacaftor in a Q1291H/F508del patient.
Katelin M Allan, Miro A Astore, Egi Kardia, Sharon L Wong, Laura K Fawcett

Front Mol Biosci· June 2023

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S945L-CFTR molecular dynamics, functional characterization and tezacaftor/ivacaftor efficacy and in matched pediatric patient-derived cell models.
Katelin M Allan, Miro A Astore, Laura K Fawcett, Sharon L Wong, Po-Chia Chen

Front Pediatr· November 2022

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Molecular Dynamics and Theratyping in Airway and Gut Organoids Reveal R352Q-CFTR Conductance Defect.
Sharon L Wong, Nikhil T Awatade, Miro A Astore, Katelin M Allan, Michael J Carnell

Am J Respir Cell Mol Biol· July 2022

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Molecular dynamics and functional characterization of I37R-CFTR lasso mutation provide insights into channel gating activity.
Sharon L Wong, Nikhil T Awatade, Miro A Astore, Katelin M Allan, Michael J Carnell

iScience· January 2022

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Global redox proteome and phosphoproteome analysis reveals redox switch in Akt.
Zhiduan Su, James G Burchfield, Pengyi Yang, Sean J Humphrey, Guang Yang, Miro A Astore

Nat Commun· December 2019

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