Publications by authors named "Misun Won"

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VHL-Mediated SYT11 Degradation Suppresses Gastric Cancer Cell Growth and Invasion Through Downregulation of SPINK1.
Ji Su Yu, Mi-Aie Hwang, Misun Won, Joo-Young Im, Dae-Hyuk Kweon

J Cell Mol Med· July 2025

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Stilbenoid derivatives as potent inhibitors of HIF-1α-centric cancer metabolism under hypoxia.
Tae-Hee Han, Joohan Lee, Dipesh S Harmalkar, Hyeseul Kang, Guanghai Jin, Su Jeong Kwon, Misun Won

Biomed Pharmacother· July 2024

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CYB5R3 functions as a tumor suppressor by inducing ER stress-mediated apoptosis in lung cancer cells via the PERK-ATF4 and IRE1α-JNK pathways.
Joo-Young Im, Soo Jin Kim, Jong-Lyul Park, Tae-Hee Han, Woo-Il Kim, Misun Won

Exp Mol Med· February 2024

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DDIAS, DNA damage-induced apoptosis suppressor, is a potential therapeutic target in cancer.
Joo-Young Im, Mi-Jung Kang, Bo-Kyung Kim, Misun Won

Exp Mol Med· May 2023

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Design, Synthesis and Biological Evaluation of Novel MDH Inhibitors Targeting Tumor Microenvironment.
Sreenivasulu Godesi, Jeong-Ran Han, Jang-Keun Kim, Dong-Ik Kwak, Joohan Lee, Misun Won

Pharmaceuticals (Basel)· May 2023

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TNF-α Secreted from Macrophages Increases the Expression of Prometastatic Integrin αV in Gastric Cancer.
Mi-Aie Hwang, Misun Won, Joo-Young Im, Mi-Jung Kang, Dae-Hyuk Kweon

Int J Mol Sci· December 2022

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DNA methylome and single-cell transcriptome analyses reveal CDA as a potential druggable target for ALK inhibitor-resistant lung cancer therapy.
Haejeong Heo, Jong-Hwan Kim, Hyun Jung Lim, Jeong-Hwan Kim, Miso Kim, Misun Won

Exp Mol Med· August 2022

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Synaptotagmin 11 scaffolds MKK7-JNK signaling process to promote stem-like molecular subtype gastric cancer oncogenesis.
Bo-Kyung Kim, Da-Mi Kim, Hyunkyung Park, Seon-Kyu Kim, Mi-Aie Hwang, Misun Won

J Exp Clin Cancer Res· June 2022

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LW1497, an Inhibitor of Malate Dehydrogenase, Suppresses TGF-β1-Induced Epithelial-Mesenchymal Transition in Lung Cancer Cells by Downregulating Slug.
Hyun Ji Kim, Mi Kyung Park, Hyun Jung Byun, Minkyoung Kim, Boram Kim, Misun Won

Antioxidants (Basel)· October 2021

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DGG-100629 inhibits lung cancer growth by suppressing the NFATc1/DDIAS/STAT3 pathway.
Joo-Young Im, Bo-Kyung Kim, Sung-Hoon Yoon, Byoung Chul Cho, Yu Mi Baek, Misun Won

Exp Mol Med· April 2021

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VGLL1 phosphorylation and activation promotes gastric cancer malignancy via TGF-β/ERK/RSK2 signaling.
Joo-Young Im, Da-Mi Kim, Hyunkyung Park, Mi-Jung Kang, Da-Yoon Kim, Misun Won

Biochim Biophys Acta Mol Cell Res· January 2021

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The disubstituted adamantyl derivative LW1564 inhibits the growth of cancer cells by targeting mitochondrial respiration and reducing hypoxia-inducible factor (HIF)-1α accumulation.
Inhyub Kim, Minkyoung Kim, Min Kyung Park, Ravi Naik, Jae Hyung Park, Misun Won

Exp Mol Med· November 2020

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Miconazole inhibits signal transducer and activator of transcription 3 signaling by preventing its interaction with DNA damage-induced apoptosis suppressor.
Sung-Hoon Yoon, Bo-Kyung Kim, Mi-Jung Kang, Joo-Young Im, Misun Won

Cancer Sci· July 2020

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DDIAS promotes STAT3 activation by preventing STAT3 recruitment to PTPRM in lung cancer cells.
Joo-Young Im, Bo-Kyung Kim, Kang-Woo Lee, So-Young Chun, Mi-Jung Kang, Misun Won

Oncogenesis· January 2020

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PI3K/AKT/β-Catenin Signaling Regulates Vestigial-Like 1 Which Predicts Poor Prognosis and Enhances Malignant Phenotype in Gastric Cancer.
Bo-Kyung Kim, Jae-Ho Cheong, Joo-Young Im, Hyun Seung Ban, Seon-Kyu Kim, Misun Won

Cancers (Basel)· December 2019

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Bcl-2-dependent synthetic lethal interaction of the IDF-11774 with the V0 subunit C of vacuolar ATPase (ATP6V0C) in colorectal cancer.
Bo-Kyung Kim, Soon Woo Nam, Byung Soh Min, Hyun Seung Ban, Soonmyung Paik, Misun Won

Br J Cancer· November 2018

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RNF25 promotes gefitinib resistance in EGFR-mutant NSCLC cells by inducing NF-κB-mediated ERK reactivation.
Jung Hee Cho, Yeon-Mi You, Y I Yeom, Dong Chul Lee, Bo-Kyung Kim, Misun Won

Cell Death Dis· May 2018

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DDIAS suppresses TRAIL-mediated apoptosis by inhibiting DISC formation and destabilizing caspase-8 in cancer cells.
Joo-Young Im, Bo-Kyung Kim, Ji-Young Lee, Seung-Ho Park, Hyun Seung Ban, Misun Won

Oncogene· March 2018

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Elasticity-based development of functionally enhanced multicellular 3D liver encapsulated in hybrid hydrogel.
Ho-Joon Lee, Myung Jin Son, Jiwon Ahn, Soo Jin Oh, Mihee Lee, Misun Won

Acta Biomater· December 2017

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Methyl 3-(3-(4-(2,4,4-Trimethylpentan-2-yl)phenoxy)-propanamido)benzoate as a Novel and Dual Malate Dehydrogenase (MDH) 1/2 Inhibitor Targeting Cancer Metabolism.
Ravi Naik, Hyun Seung Ban, Kyusic Jang, Inhyub Kim, Xuezhen Xu, Misun Won

J Med Chem· October 2017

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Synthesis and biological evaluation of kresoxim-methyl analogues as novel inhibitors of hypoxia-inducible factor (HIF)-1 accumulation in cancer cells.
Sanghyuck Lee, Oh Seok Kwon, Chang-Soo Lee, Misun Won, Hyun Seung Ban

Bioorg Med Chem Lett· July 2017

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The novel hypoxia-inducible factor-1α inhibitor IDF-11774 regulates cancer metabolism, thereby suppressing tumor growth.
Hyun Seung Ban, Bo-Kyung Kim, Hongsub Lee, Hwan Mook Kim, Dipesh Harmalkar, Misun Won

Cell Death Dis· June 2017

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Stability of the cancer target DDIAS is regulated by the CHIP/HSP70 pathway in lung cancer cells.
Kyoung-Jae Won, Joo-Young Im, Bo-Kyung Kim, Hyun Seung Ban, Young-Jin Jung, Misun Won

Cell Death Dis· January 2017

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Data on the transcriptional regulation of DNA damage induced apoptosis suppressor (DDIAS) by ERK5/MEF2B pathway in lung cancer cells.
Joo-Young Im, Sung-Hoon Yoon, Bo-Kyung Kim, Hyun Seung Ban, Kyoung-Jae Won, Misun Won

Data Brief· December 2016

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DNA damage induced apoptosis suppressor (DDIAS) is upregulated via ERK5/MEF2B signaling and promotes β-catenin-mediated invasion.
Joo-Young Im, Sung-Hoon Yoon, Bo-Kyung Kim, Hyun Seung Ban, Kyoung-Jae Won, Misun Won

Biochim Biophys Acta· November 2016

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