Publications by authors named "Mitchell C Lock"

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Elevated cortisol concentration in preterm sheep fetuses impacts heart development.
Reza Amanollahi, Stacey L Holman, Melanie R Bertossa, Ashley S Meakin, Vicki L Clifton, Mitchell C Lock

Exp Physiol· December 2025

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Mitochondrial metabolic remodeling and multi-omics profiling identify plasma biomarkers of myocardial infarction.
Selvam Paramasivan, Mitchell C Lock, Roberto A Barrero, Paul C Mills, Janna L Morrison

J Mol Cell Cardiol Plus· December 2025

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Sex-specific effects of betamethasone on glucocorticoid and apoptotic signalling pathways in the sheep placenta.
Ashley S Meakin, Mitchell C Lock, Stacey L Holman, Joshua L Robinson, Vicki L Clifton

J Physiol· September 2025

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Antenatal betamethasone impairs markers of cardiac development and function in near-term lambs.
Reza Amanollahi, Ashley S Meakin, Stacey L Holman, Vicki L Clifton, Kent L Thornburg, Mitchell C Lock

Exp Physiol· September 2025

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Embryo Culture Impacts Heart Mitochondria in Male Adolescent Sheep.
Reza Amanollahi, Stacey L Holman, Ashley S Meakin, Monalisa Padhee, Kimberley J Botting-Lawford, Mitchell C Lock

J Dev Biol· May 2025

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Fetal glucose availability: a key regulator of the metabolic, hormonal and contractility profiles of the fetal sheep heart.
Melanie R Bertossa, Jack R T Darby, Stacey L Holman, Steven K S Cho, Ashley S Meakin, Mitchell C Lock

J Physiol· May 2025

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Pregnancy does not affect progression of mild experimental asthma in sheep.
Andrea J Roff, Andrew N Davies, Vicki L Clifton, Michael J Stark, Andrew Tai, Mitchell C Lock

J Physiol· March 2025

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Ontogeny of Fetal Cardiometabolic Pathways: The Potential Role of Cortisol and Thyroid Hormones in Driving the Transition from Preterm to Near-Term Heart Development in Sheep.
Reza Amanollahi, Stacey L Holman, Melanie R Bertossa, Ashley S Meakin, Kent L Thornburg, Mitchell C Lock

J Cardiovasc Dev Dis· January 2025

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Late-gestation maternal undernutrition induces circulatory redistribution while preserving uteroplacental function independent of fetal glycaemic state.
Steven K S Cho, Jack R T Darby, Brahmdeep S Saini, Stacey L Holman, Mitchell C Lock

J Physiol· December 2024

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Maladaptive cardiomyocyte calcium handling in adult offspring of hypoxic pregnancy: protection by antenatal maternal melatonin.
Mitchell C Lock, Olga V Patey, Kerri L M Smith, Youguo Niu, Ben Jaggs

J Physiol· December 2024

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Developmental plasticity of the cardiovascular system in oviparous vertebrates: effects of chronic hypoxia and interactive stressors in the context of climate change.
Mitchell C Lock, Daniel M Ripley, Kerri L M Smith, Casey A Mueller, Holly A Shiels

J Exp Biol· October 2024

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Cardiac programming in the placentally restricted sheep fetus in early gestation.
Song Zhang, Mitchell C Lock, Michelle Tie, I Caroline McMillen, Kimberley J Botting

J Physiol· August 2024

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Sex-specific effects of culture and embryo transfer on cardiac growth in sheep offspring.
Monalisa Padhee, Mitchell C Lock, I Caroline McMillen, Song Zhang, Kimberley J Botting

J Mol Cell Cardiol Plus· September 2023

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MitoQ as an antenatal antioxidant treatment improves markers of lung maturation in healthy and hypoxic pregnancy.
Mitchell C Lock, Kimberley J Botting, Beth J Allison, Youguo Niu, Sage G Ford

J Physiol· August 2023

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Automated Proteomics Workflows for High-Throughput Library Generation and Biomarker Detection Using Data-Independent Acquisition.
Selvam Paramasivan, Janna L Morrison, Mitchell C Lock, Jack R T Darby, Roberto A Barrero

J Proteome Res· June 2023

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Effects of Developmental Hypoxia on the Vertebrate Cardiovascular System.
Gina L J Galli, Mitchell C Lock, Kerri L M Smith, Dino A Giussani, Dane A Crossley

Physiology (Bethesda)· March 2023

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Chronic developmental hypoxia alters mitochondrial oxidative capacity and reactive oxygen species production in the fetal rat heart in a sex-dependent manner.
Kerri L M Smith, Agnieszka Swiderska, Mitchell C Lock, Lucia Graham, Wulan Iswari

J Pineal Res· October 2022

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Maternal melatonin: Effective intervention against developmental programming of cardiovascular dysfunction in adult offspring of complicated pregnancy.
Jeremy A Hansell, Hans G Richter, Emily J Camm, Emilio A Herrera, Carlos E Blanco, Mitchell C Lock

J Pineal Res· January 2022

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PPARγ activation in late gestation does not promote surfactant maturation in the fetal sheep lung.
Jiaqi Ren, Mitchell C Lock, Jack R T Darby, Sandra Orgeig, Stacey L Holman

J Dev Orig Health Dis· December 2021

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Intrauterine growth restriction alters the activity of drug metabolising enzymes in the maternal-placental-fetal unit.
Grace M McBride, Ashley S Meakin, Jia Yin Soo, Jack R T Darby, Tamara J Varcoe, Mitchell C Lock

Life Sci· November 2021

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Impact of maternal late gestation undernutrition on surfactant maturation, pulmonary blood flow and oxygen delivery measured by magnetic resonance imaging in the sheep fetus.
Jiaqi Ren, Jack R T Darby, Mitchell C Lock, Stacey L Holman, Brahmdeep S Saini

J Physiol· October 2021

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Open or closed: Changes in ductus arteriosus flow patterns at birth using 4D flow MRI in newborn piglets.
Eric M Schrauben, Jack R T Darby, Mary J Berry, Brahmdeep S Saini, Megan Quinn, Mitchell C Lock

Physiol Rep· September 2021

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Impact of resveratrol-mediated increase in uterine artery blood flow on fetal haemodynamics, blood pressure and oxygenation in sheep.
Tanroop Aujla, Jack R T Darby, Brahmdeep S Saini, Mitchell C Lock, Stacey L Holman

Exp Physiol· May 2021

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An MRI approach to assess placental function in healthy humans and sheep.
Brahmdeep S Saini, Jack R T Darby, Davide Marini, Sharon Portnoy, Mitchell C Lock

J Physiol· May 2021

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Identification of Novel miRNAs Involved in Cardiac Repair Following Infarction in Fetal and Adolescent Sheep Hearts.
Mitchell C Lock, Ross L Tellam, Jack R T Darby, Jia Yin Soo, Doug A Brooks

Front Physiol· June 2020

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