Publications by authors named "Mitchell Wayne"

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Understanding Injury Patterns and Predictors in Pickleball Players: A Nationwide Study of 1,758 Participants.
Oluwatoyosi B A Owoeye, Ted Yemm, Ryan Blechle, Mitchell Wayne, Dawn Kennedy

Sports Med Open· August 2025

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The 18S rRNA methyltransferase DIMT-1 regulates lifespan in the germline later in life.
M Hafiz Rothi, Gautam Chandra Sarkar, Joseph Al Haddad, Wayne Mitchell, Kejun Ying

Nat Commun· July 2025

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The Mitochondria-Targeted Peptide Therapeutic Elamipretide Improves Cardiac and Skeletal Muscle Function During Aging Without Detectable Changes in Tissue Epigenetic or Transcriptomic Age.
Wayne Mitchell, Gavin Pharaoh, Alexander Tyshkovskiy, Matthew Campbell, David J Marcinek

Aging Cell· June 2025

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chemical reprogramming is associated with a toxic accumulation of lipid droplets hindering rejuvenation.
Wayne Mitchell, Cecília G de Magalhães, Alexander Tyshkovskiy, Yushi Uchida, Ludger J E Goeminne

bioRxiv· June 2025

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Disagreement on foundational principles of biological aging.
Vadim N Gladyshev, Benjamin Anderson, Hanna Barlit, Benjamin Barré, Samuel Beck, Wayne Mitchell

PNAS Nexus· December 2024

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Perturbations in mitochondrial metabolism associated with defective cardiolipin biosynthesis: An in-organello real-time NMR study.
Antonio J Rua, Wayne Mitchell, Steven M Claypool, Nathan N Alder, Andrei T Alexandrescu

J Biol Chem· October 2024

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The mitochondrial-targeted peptide therapeutic elamipretide improves cardiac and skeletal muscle function during aging without detectable changes in tissue epigenetic or transcriptomic age.
Wayne Mitchell, Gavin Pharaoh, Alexander Tyshkovskiy, Matthew Campbell, David J Marcinek

bioRxiv· October 2024

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Risk of inflammatory bowel disease following hospitalisation with infectious mononucleosis: nationwide cohort study from Denmark.
Anthony C Ebert, Shania Harper, Marie V Vestergaard, Wayne Mitchell, Tine Jess

Nat Commun· September 2024

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The 18S rRNA Methyltransferase DIMT-1 Regulates Lifespan in the Germline Later in Life.
M Hafiz Rothi, Joseph Al Haddad, Gautam Chandra Sarkar, Wayne Mitchell, Kejun Ying

Res Sq· June 2024

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Perturbations in mitochondrial metabolism associated with defective cardiolipin biosynthesis: An real-time NMR study.
Antonio J Rua, Wayne Mitchell, Steven M Claypool, Nathan N Alder, Andrei T Alexandrescu

bioRxiv· June 2024

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Phylogenomics and genetic analysis of solvent-producing Clostridium species.
Rasmus O Jensen, Frederik Schulz, Simon Roux, Dawn M Klingeman, Wayne P Mitchell

Sci Data· May 2024

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The 18S rRNA Methyltransferase DIMT-1 Regulates Lifespan in the Germline Later in Life.
M Hafiz Rothi, Gautam Chandra Sarkar, Joseph Al Haddad, Wayne Mitchell, Kejun Ying

bioRxiv· May 2024

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Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation.
Wayne Mitchell, Ludger J E Goeminne, Alexander Tyshkovskiy, Sirui Zhang, Julie Y Chen

Elife· March 2024

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Expanding the synthetic biology toolbox of Cupriavidus necator for establishing fatty acid production.
Shivangi Mishra, Paul M Perkovich, Wayne P Mitchell, Maya Venkataraman, Brian F Pfleger

J Ind Microbiol Biotechnol· January 2024

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Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation.
Wayne Mitchell, Ludger J E Goeminne, Alexander Tyshkovskiy, Sirui Zhang, Julie Y Chen

bioRxiv· November 2023

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Interactions of amyloidogenic proteins with mitochondrial protein import machinery in aging-related neurodegenerative diseases.
Ashley L Reed, Wayne Mitchell, Andrei T Alexandrescu, Nathan N Alder

Front Physiol· November 2023

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The role of CD8+ T-cell clones in immune thrombocytopenia.
Amna Malik, Anwar A Sayed, Panpan Han, Michelle M H Tan, Eleanor Watt, Wayne A Mitchell

Blood· May 2023

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Structure-activity relationships of mitochondria-targeted tetrapeptide pharmacological compounds.
Wayne Mitchell, Jeffrey D Tamucci, Emery L Ng, Shaoyi Liu, Alexander V Birk

Elife· August 2022

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isopropanol production native plasmid pCA replicon.
Robert Nogle, Shilpa Nagaraju, Sagar M Utturkar, Richard J Giannone, Vinicio Reynoso, Wayne P Mitchell

Front Bioeng Biotechnol· August 2022

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The mitochondria-targeted peptide SS-31 binds lipid bilayers and modulates surface electrostatics as a key component of its mechanism of action.
Wayne Mitchell, Emily A Ng, Jeffrey D Tamucci, Kevin J Boyd, Murugappan Sathappa

J Biol Chem· May 2020

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Comparison of single-molecule sequencing and hybrid approaches for finishing the genome of Clostridium autoethanogenum and analysis of CRISPR systems in industrial relevant Clostridia.
Steven D Brown, Shilpa Nagaraju, Sagar Utturkar, Sashini De Tissera, Simón Segovia, Wayne Mitchell

Biotechnol Biofuels· May 2014

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Genomic reconnaissance of clinical isolates of emerging human pathogen Mycobacterium abscessus reveals high evolutionary potential.
Siew Woh Choo, Wei Yee Wee, Yun Fong Ngeow, Wayne Mitchell, Joon Liang Tan

Sci Rep· February 2014

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Reconsidering Dispersion Potentials: Reduced Cutoffs in Mesh-Based Ewald Solvers Can Be Faster Than Truncation.
Rolf E Isele-Holder, Wayne Mitchell, Jeff R Hammond, Axel Kohlmeyer, Ahmed E Ismail

J Chem Theory Comput· December 2013

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Development and application of a particle-particle particle-mesh Ewald method for dispersion interactions.
Rolf E Isele-Holder, Wayne Mitchell, Ahmed E Ismail

J Chem Phys· November 2012

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Pulmonary delivery of interleukin-7 provides efficient and safe delivery to the aging immune system.
Wayne A Mitchell, Aina Castells, Pierre Olivier Lang, Emmanuel Matas, Antonio Lapenna

Rejuvenation Res· August 2012

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