Publications by authors named "Mithun Raje"

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SS-4 is a highly selective small molecule inhibitor of STAT3 tyrosine phosphorylation that potently inhibits GBM tumorigenesis in vitro and in vivo.
Yinan Wang, Chuanhe Yang, Michelle M Sims, Joshua R Sacher, Mithun Raje

Cancer Lett· May 2022

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CG223, a novel BET inhibitor, exerts TGF-β1-mediated antifibrotic effects in a murine model of bleomycin-induced pulmonary fibrosis.
Shunya Kaneshita, Takashi Kida, Makoto Yoshioka, Keisuke Nishioka, Mithun Raje

Pulm Pharmacol Ther· October 2021

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Discovery of Mcl-1 inhibitors based on a thiazolidine-2,4-dione scaffold.
Ellis Whiting, Mithun R Raje, Jay Chauhan, Paul T Wilder, Daniel Van Eker

Bioorg Med Chem Lett· February 2018

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Flex-nucleoside analogues - Novel therapeutics against filoviruses.
Mary K Yates, Mithun R Raje, Payel Chatterjee, Christina F Spiropoulou, Sina Bavari

Bioorg Med Chem Lett· June 2017

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Synthetic, structural mimetics of the β-hairpin flap of HIV-1 protease inhibit enzyme function.
Jay Chauhan, Shen-En Chen, Katherine J Fenstermacher, Aurash Naser-Tavakolian, Tali Reingewertz, Mithun Raje

Bioorg Med Chem· November 2015

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BRD4 Structure-Activity Relationships of Dual PLK1 Kinase/BRD4 Bromodomain Inhibitor BI-2536.
Lijia Chen, Jeremy L Yap, Makoto Yoshioka, Maryanna E Lanning, Rachel N Fountain, Mithun Raje

ACS Med Chem Lett· July 2015

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Structure-activity relationship studies and in vivo activity of guanidine-based sphingosine kinase inhibitors: discovery of SphK1- and SphK2-selective inhibitors.
Neeraj N Patwardhan, Emily A Morris, Yugesh Kharel, Mithun R Raje, Ming Gao

J Med Chem· February 2015

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Molecular mechanisms of 5-HT(3) and NK(1) receptor antagonists in prevention of emesis.
Camilo Rojas, Mithun Raje, Takashi Tsukamoto, Barbara S Slusher

Eur J Pharmacol· January 2014

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Synthesis of kojic acid derivatives as secondary binding site probes of D-amino acid oxidase.
Mithun Raje, Niyada Hin, Bridget Duvall, Dana V Ferraris, James F Berry

Bioorg Med Chem Lett· July 2013

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Effect of alkyl chain length on sphingosine kinase 2 selectivity.
Kenneth Knott, Yugesh Kharel, Mithun R Raje, Kevin R Lynch, Webster L Santos

Bioorg Med Chem Lett· November 2012

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Sphingosine kinase type 2 inhibition elevates circulating sphingosine 1-phosphate.
Yugesh Kharel, Mithun Raje, Ming Gao, Amanda M Gellett, Jose L Tomsig

Biochem J· October 2012

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Design, synthesis and biological activity of sphingosine kinase 2 selective inhibitors.
Mithun R Raje, Kenneth Knott, Yugesh Kharel, Philippe Bissel, Kevin R Lynch

Bioorg Med Chem· January 2012

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