Publications by authors named "Mitsuhiro Nishimoto"

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Lipid Management for Secondary Prevention in Atherosclerotic Cardiovascular Disease: A Scoping Review and Scientific Report.
Atsushi Tanaka, Kazuma Oyama, Yusuke Yakushiji, Masahiro Natsuaki, Atsushi Mizuno, Mitsuhiro Nishimoto

J Atheroscler Thromb· December 2025

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Real-world use of finerenone in patients with chronic kidney disease and type 2 diabetes based on large-scale clinical studies: FIDELIO-DKD and FIGARO-DKD.
Atsuhisa Sato, Mitsuhiro Nishimoto

Hypertens Res· June 2025

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Aberrant proximal tubule DNA methylation underlies phenotypic changes related to kidney dysfunction in patients with diabetes.
Takeshi Marumo, Naoto Yoshida, Noriko Inoue, Masayuki Yamanouchi, Yoshifumi Ubara, Mitsuhiro Nishimoto

Am J Physiol Renal Physiol· September 2024

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Salt-Sensitive Hypertension and the Kidney.
Mitsuhiro Nishimoto, Karen A Griffin, Brandi M Wynne, Toshiro Fujita

Hypertension· June 2024

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Rac1 deficiency impairs postnatal development of the renal papilla.
Nobuhiro Ayuzawa, Mitsuhiro Nishimoto, Wakako Kawarazaki, Shigeyoshi Oba, Takeshi Marumo

Sci Rep· November 2022

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Clinical effect of nonsteroidal mineralocorticoid receptor (MR) antagonists in the treatment of diabetic kidney disease: expectations as a new therapeutic strategy.
Atsuhisa Sato, Mitsuhiro Nishimoto

Hypertens Res· August 2022

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Activation of Rac1-Mineralocorticoid Receptor Pathway Contributes to Renal Injury in Salt-Loaded Mice.
Daigoro Hirohama, Mitsuhiro Nishimoto, Nobuhiro Ayuzawa, Wakako Kawarazaki, Wataru Fujii

Hypertension· July 2021

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Methylation pattern of urinary DNA as a marker of kidney function decline in diabetes.
Takeshi Marumo, Junichi Hoshino, Wakako Kawarazaki, Mitsuhiro Nishimoto, Nobuhiro Ayuzawa

BMJ Open Diabetes Res Care· September 2020

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Salt causes aging-associated hypertension via vascular Wnt5a under Klotho deficiency.
Wakako Kawarazaki, Risuke Mizuno, Mitsuhiro Nishimoto, Nobuhiro Ayuzawa, Daigoro Hirohama

J Clin Invest· August 2020

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PGI Analog Attenuates Salt-Induced Renal Injury through the Inhibition of Inflammation and Rac1-MR Activation.
Daigoro Hirohama, Wakako Kawarazaki, Mitsuhiro Nishimoto, Nobuhiro Ayuzawa, Takeshi Marumo

Int J Mol Sci· June 2020

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Two Mineralocorticoid Receptor-Mediated Mechanisms of Pendrin Activation in Distal Nephrons.
Nobuhiro Ayuzawa, Mitsuhiro Nishimoto, Kohei Ueda, Daigoro Hirohama, Wakako Kawarazaki

J Am Soc Nephrol· April 2020

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Mineralocorticoid receptor blockade suppresses dietary salt-induced ACEI/ARB-resistant albuminuria in non-diabetic hypertension: a sub-analysis of evaluate study.
Mitsuhiro Nishimoto, Hiroshi Ohtsu, Takeshi Marumo, Wakako Kawarazaki, Nobuhiro Ayuzawa

Hypertens Res· April 2019

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Aberrant DNA methylation of hypothalamic angiotensin receptor in prenatal programmed hypertension.
Fumiko Kawakami-Mori, Mitsuhiro Nishimoto, Latapati Reheman, Wakako Kawarazaki, Nobuhiro Ayuzawa

JCI Insight· November 2018

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Aberrant DNA methylation of Tgfb1 in diabetic kidney mesangial cells.
Shigeyoshi Oba, Nobuhiro Ayuzawa, Mitsuhiro Nishimoto, Wakako Kawarazaki, Kohei Ueda

Sci Rep· November 2018

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Stromal interaction molecule 1 modulates blood pressure via NO production in vascular endothelial cells.
Mitsuhiro Nishimoto, Risuke Mizuno, Toshiro Fujita, Masashi Isshiki

Hypertens Res· July 2018

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Aberrant DNA methylation of pregnane X receptor underlies metabolic gene alterations in the diabetic kidney.
Atsushi Watanabe, Takeshi Marumo, Wakako Kawarazaki, Mitsuhiro Nishimoto, Nobuhiro Ayuzawa

Am J Physiol Renal Physiol· April 2018

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Aldosterone Is Essential for Angiotensin II-Induced Upregulation of Pendrin.
Daigoro Hirohama, Nobuhiro Ayuzawa, Kohei Ueda, Mitsuhiro Nishimoto, Wakako Kawarazaki

J Am Soc Nephrol· January 2018

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Renal Dysfunction Induced by Kidney-Specific Gene Deletion of as a Primary Cause of Salt-Dependent Hypertension.
Kohei Ueda, Mitsuhiro Nishimoto, Daigoro Hirohama, Nobuhiro Ayuzawa, Wakako Kawarazaki

Hypertension· July 2017

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Rac1-Mediated Activation of Mineralocorticoid Receptor in Pressure Overload-Induced Cardiac Injury.
Nobuhiro Ayuzawa, Miki Nagase, Kohei Ueda, Mitsuhiro Nishimoto, Wakako Kawarazaki

Hypertension· January 2016

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Diabetes Induces Aberrant DNA Methylation in the Proximal Tubules of the Kidney.
Takeshi Marumo, Shintaro Yagi, Wakako Kawarazaki, Mitsuhiro Nishimoto, Nobuhiro Ayuzawa

J Am Soc Nephrol· October 2015

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A High-Salt Diet Differentially Modulates Mechanical Activity of Afferent and Efferent Collecting Lymphatics in Murine Iliac Lymph Nodes.
Risuke Mizuno, Masashi Isshiki, Nobuyuki Ono, Mitsuhiro Nishimoto, Toshiro Fujita

Lymphat Res Biol· June 2015

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Renal mechanisms of salt-sensitive hypertension: contribution of two steroid receptor-associated pathways.
Mitsuhiro Nishimoto, Toshiro Fujita

Am J Physiol Renal Physiol· March 2015

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A high salt diet alters pressure-induced mechanical activity of the rat lymphatics with enhancement of myogenic characteristics.
Risuke Mizuno, Masashi Isshiki, Nobuyuki Ono, Mitsuhiro Nishimoto, Toshiro Fujita

Lymphat Res Biol· March 2015

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FRET-based sensor analysis reveals caveolae are spatially distinct Ca2+ stores in endothelial cells.
Masashi Isshiki, Mitsuhiro Nishimoto, Risuke Mizuno, Toshiro Fujita

Cell Calcium· December 2013

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