Publications by authors named "Mitsutaka Kitano"

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Pharmacokinetic and pharmacodynamic analysis of baloxavir marboxil, a novel cap-dependent endonuclease inhibitor, in a murine model of influenza virus infection.
Yoshinori Ando, Takeshi Noshi, Kenji Sato, Toru Ishibashi, Yuki Yoshida, Mitsutaka Kitano

J Antimicrob Chemother· January 2021

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The antiviral effects of baloxavir marboxil against influenza A virus infection in ferrets.
Mitsutaka Kitano, Takanobu Matsuzaki, Ryoko Oka, Kaoru Baba, Takahiro Noda

Influenza Other Respir Viruses· November 2020

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Baloxavir marboxil, a novel cap-dependent endonuclease inhibitor potently suppresses influenza virus replication and represents therapeutic effects in both immunocompetent and immunocompromised mouse models.
Keita Fukao, Yoshinori Ando, Takeshi Noshi, Mitsutaka Kitano, Takahiro Noda

PLoS One· February 2020

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Antibody dynamics in Japanese paediatric patients with influenza A infection treated with neuraminidase inhibitors in a randomised trial.
Nobuo Hirotsu, Yutaka Saisho, Takahiro Hasegawa, Mitsutaka Kitano, Takao Shishido

Sci Rep· August 2019

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Combination treatment with the cap-dependent endonuclease inhibitor baloxavir marboxil and a neuraminidase inhibitor in a mouse model of influenza A virus infection.
Keita Fukao, Takeshi Noshi, Atsuko Yamamoto, Mitsutaka Kitano, Yoshinori Ando

J Antimicrob Chemother· March 2019

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In vitro characterization of baloxavir acid, a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit.
Takeshi Noshi, Mitsutaka Kitano, Keiichi Taniguchi, Atsuko Yamamoto, Shinya Omoto

Antiviral Res· December 2018

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Selection and Characterization of Rupintrivir-Resistant Norwalk Virus Replicon Cells .
Mitsutaka Kitano, Myra Hosmillo, Edward Emmott, Jia Lu, Ian Goodfellow

Antimicrob Agents Chemother· May 2018

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The effect of intravenous peramivir, compared with oral oseltamivir, on the outcome of post-influenza pneumococcal pneumonia in mice.
Akitaka Tanaka, Shigeki Nakamura, Masafumi Seki, Naoki Iwanaga, Toshiki Kajihara, Mitsutaka Kitano

Antivir Ther· November 2015

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Intravenous peramivir inhibits viral replication, and leads to bacterial clearance and prevention of mortality during murine bacterial co-infection caused by influenza A(H1N1)pdm09 virus and Streptococcus pneumoniae.
Motoyasu Onishi, Mitsutaka Kitano, Keiichi Taniguchi, Tomoyuki Homma, Masanori Kobayashi

Antiviral Res· May 2015

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Protection against H5N1 highly pathogenic avian and pandemic (H1N1) 2009 influenza virus infection in cynomolgus monkeys by an inactivated H5N1 whole particle vaccine.
Misako Nakayama, Shintaro Shichinohe, Yasushi Itoh, Hirohito Ishigaki, Mitsutaka Kitano

PLoS One· March 2015

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Hydroxypropyl-β-cyclodextrin spikes local inflammation that induces Th2 cell and T follicular helper cell responses to the coadministered antigen.
Motoyasu Onishi, Koji Ozasa, Kouji Kobiyama, Keiichi Ohata, Mitsutaka Kitano

J Immunol· March 2015

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The relationship between in vivo antiviral activity and pharmacokinetic parameters of peramivir in influenza virus infection model in mice.
Makoto Kodama, Ryu Yoshida, Takahiro Hasegawa, Masaaki Izawa, Mitsutaka Kitano

Antiviral Res· September 2014

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Efficacy of repeated intravenous administration of peramivir against highly pathogenic avian influenza A (H5N1) virus in cynomolgus macaques.
Mitsutaka Kitano, Yasushi Itoh, Hirohito Ishigaki, Misako Nakayama, Hideaki Ishida

Antimicrob Agents Chemother· August 2014

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Pathogenicity of pandemic H1N1 influenza A virus in immunocompromised cynomolgus macaques.
Van Loi Pham, Misako Nakayama, Yasushi Itoh, Hirohito Ishigaki, Mitsutaka Kitano

PLoS One· July 2014

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Protective efficacy of passive immunization with monoclonal antibodies in animal models of H5N1 highly pathogenic avian influenza virus infection.
Yasushi Itoh, Reiko Yoshida, Shintaro Shichinohe, Megumi Higuchi, Hirohito Ishigaki, Mitsutaka Kitano

PLoS Pathog· June 2014

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Hemozoin is a potent adjuvant for hemagglutinin split vaccine without pyrogenicity in ferrets.
Motoyasu Onishi, Mitsutaka Kitano, Keiichi Taniguchi, Tomoyuki Homma, Masanori Kobayashi

Vaccine· May 2014

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Efficacy of repeated intravenous injection of peramivir against influenza A (H1N1) 2009 virus infection in immunosuppressed mice.
Mitsutaka Kitano, Makoto Kodama, Yasushi Itoh, Takushi Kanazu, Masanori Kobayashi

Antimicrob Agents Chemother· May 2013

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Efficacy of single intravenous injection of peramivir against influenza B virus infection in ferrets and cynomolgus macaques.
Mitsutaka Kitano, Yasushi Itoh, Makoto Kodama, Hirohito Ishigaki, Misako Nakayama

Antimicrob Agents Chemother· November 2011

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Establishment of a cynomolgus macaque model of influenza B virus infection.
Mitsutaka Kitano, Yasushi Itoh, Makoto Kodama, Hirohito Ishigaki, Misako Nakayama

Virology· November 2010

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Selection of escape mutation by Pol154-162-specific cytotoxic T cells among chronically HIV-1-infected HLA-B*5401-positive individuals.
Masao Hashimoto, Mitsutaka Kitano, Kazutaka Honda, Hirokazu Koizumi, Sachi Dohki

Hum Immunol· February 2010

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Identification and characterization of 2 HIV-1 Gag immunodominant epitopes restricted by Asian HLA allele HLA-B*4801.
Hayato Murakoshi, Mitsutaka Kitano, Tomohiro Akahoshi, Yuka Kawashima, Sachi Dohki

Hum Immunol· March 2009

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Identification and characterization of HLA-B*5401-restricted HIV-1-Nef and Pol-specific CTL epitopes.
Mitsutaka Kitano, Naoki Kobayashi, Yuka Kawashima, Tomohiro Akahoshi, Kiyoshi Nokihara

Microbes Infect· June 2008

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