Publications by authors named "Modesto J Remuinan"

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High-throughput screening of small molecules targeting in human iPSC macrophages.
Alejandro Armesilla-Diaz, María Pilar Arenaz, Charlotte Ashby, Delia Blanco, Emiliana D'Oria

Antimicrob Agents Chemother· July 2025

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First-in-human study of alpibectir (BVL-GSK098), a novel potent anti-TB drug.
Michel Pieren, Ana Abáigar Gutiérrez-Solana, Rosa María Antonijoan Arbós, Gary W Boyle, Myriam Davila

J Antimicrob Chemother· June 2024

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The small-molecule SMARt751 reverses resistance to ethionamide in acute and chronic mouse models of tuberculosis.
Marion Flipo, Rosangela Frita, Marilyne Bourotte, María S Martínez-Martínez, Markus Boesche

Sci Transl Med· May 2022

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THPP target assignment reveals EchA6 as an essential fatty acid shuttle in mycobacteria.
Jonathan A G Cox, Katherine A Abrahams, Carlos Alemparte, Sonja Ghidelli-Disse, Joaquín Rullas

Nat Microbiol· January 2016

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Mycobacterium tuberculosis gyrase inhibitors as a new class of antitubercular drugs.
Delia Blanco, Esther Perez-Herran, Mónica Cacho, Lluís Ballell, Julia Castro

Antimicrob Agents Chemother· April 2015

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Encoded library technology as a source of hits for the discovery and lead optimization of a potent and selective class of bactericidal direct inhibitors of Mycobacterium tuberculosis InhA.
Lourdes Encinas, Heather O'Keefe, Margarete Neu, Modesto J Remuiñán, Amish M Patel

J Med Chem· February 2014

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Tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide and N-benzyl-6',7'-dihydrospiro[piperidine-4,4'-thieno[3,2-c]pyran] analogues with bactericidal efficacy against Mycobacterium tuberculosis targeting MmpL3.
Modesto J Remuiñán, Esther Pérez-Herrán, Joaquín Rullás, Carlos Alemparte, María Martínez-Hoyos

PLoS One· November 2013

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Identification of novel imidazo[1,2-a]pyridine inhibitors targeting M. tuberculosis QcrB.
Katherine A Abrahams, Jonathan A G Cox, Vickey L Spivey, Nicholas J Loman, Mark J Pallen

PLoS One· June 2013

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Asymmetric aza-Henry reactions from N-p-tolylsulfinylimines.
José Luis García Ruano, Markus Topp, Jesús López-Cantarero, José Alemán, Modesto J Remuiñán

Org Lett· September 2005

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