Publications by authors named "Mohammed Al Hallak"

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PCNA Inhibition Enhances the Antitumor Activity of KRAS-Targeted Therapies in Pancreatic Cancer.
Sahar F Bannoura, Husain Yar Khan, Amro Aboukameel, Yin Wan, Bin Bao, Mohammed Najeeb Al Hallak

bioRxiv· December 2025

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Co-targeting KRAS and Exportin1 as an effective therapeutic strategy for KRASG12D mutant pancreatic ductal adenocarcinoma.
Husain Yar Khan, Mohammed Najeeb Al Hallak, Amro Aboukameel, Sahar F Bannoura, Md Hafiz Uddin

bioRxiv· November 2025

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XPO1 inhibition in KRAS-mutant cancers: time for clinical trials but how?
Misako Nagasaka, Husain Y Khan, Faustine Luo, Mohammed Najeeb Al-Hallak, Muhammad Wasif Saif

Transl Lung Cancer Res· August 2025

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Multiomic Characterization of and Expression and Their Association With Molecular Alterations, Immune Phenotypes, and Cancer Outcomes.
Misako Nagasaka, Brian Warnecke, Sai-Hong Ignatius Ou, Sahar F Bannoura, Chul Kim, Mohammed Najeeb Al-Hallak

JCO Oncol Adv· May 2025

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Association between cannabis use and clinical outcomes in patients with solid malignancies receiving immune checkpoint inhibitors.
Tarik Hadid, Adam Biedny, Hirva Mamdani, Asfar Azmi, Seongho Kim, Mohammed Najeeb Al Hallak

Ther Adv Vaccines Immunother· December 2024

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RCC1 regulation of subcellular protein localization via Ran GTPase drives pancreatic ductal adenocarcinoma growth.
Sahar F Bannoura, Amro Aboukameel, Husain Yar Khan, Md Hafiz Uddin, Hyejeong Jang, Mohammed Najeeb Al-Hallak

Cancer Lett· November 2024

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Health Disparities among Patients with Cancer Who Received Molecular Testing for Biomarker-Directed Therapy.
Elisabeth Heath, Gregory Dyson, Jennifer R Ribeiro, Joanne Xiu, Kelsey Poorman, Mohammed N Al-Hallak

Cancer Res Commun· October 2024

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Gastric Cancer Survivorship: Multidisciplinary Management, Best Practices and Opportunities.
Era Cobani, Mohammed Najeeb Al Hallak, Anthony F Shields, Jordan Maier, Thomas E Kelly

J Gastrointest Cancer· June 2024

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The phase I/II eNRGy trial: Zenocutuzumab in patients with cancers harboring gene fusions.
Dong-Wan Kim, Alison M Schram, Antoine Hollebecque, Kazumi Nishino, Teresa Macarulla, Mohammed Najeeb Al Hallak

Future Oncol· June 2024

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Anticancer Efficacy of KRASG12C Inhibitors Is Potentiated by PAK4 Inhibitor KPT9274 in Preclinical Models of KRASG12C-Mutant Pancreatic and Lung Cancers.
Husain Yar Khan, Misako Nagasaka, Amro Aboukameel, Osama Alkhalili, Md Hafiz Uddin, Mohammed Najeeb Al Hallak

Mol Cancer Ther· December 2023

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Regulator of Chromosome Condensation (RCC1) a novel therapeutic target in pancreatic ductal adenocarcinoma drives tumor progression via the c-Myc-RCC1-Ran axis.
Sahar F Bannoura, Amro Aboukameel, Husain Yar Khan, Md Hafiz Uddin, Hyejeong Jang, Mohammed Najeeb Al-Hallak

bioRxiv· December 2023

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Pan-tumor survey of RET fusions as detected by next-generation RNA sequencing identified RET fusion positive colorectal carcinoma as a unique molecular subset.
Misako Nagasaka, Danielle Brazel, Yasmine Baca, Joanne Xiu, Mohammed Najeeb Al-Hallak

Transl Oncol· October 2023

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Primary Squamous Cell Biliary Carcinoma With Liver Metastasis Is Rare but Malicious.
Mohamad Khaled Almujarkesh, Anirudh R Damughatla, Jasdeep Bathla, Kyle Sugg, Dana LaBuda, Mohammed Najeeb Al Hallak

Gastroenterology Res· October 2023

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Anticancer efficacy of KRASG12C inhibitors is potentiated by PAK4 inhibitor KPT9274 in preclinical models of KRASG12C mutant pancreatic and lung cancers.
Husain Yar Khan, Misako Nagasaka, Amro Aboukameel, Osama Alkhalili, Md Hafiz Uddin, Mohammed Najeeb Al-Hallak

bioRxiv· March 2023

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Inhibitor of the Nuclear Transport Protein XPO1 Enhances the Anticancer Efficacy of KRAS G12C Inhibitors in Preclinical Models of KRAS G12C-Mutant Cancers.
Husain Yar Khan, Misako Nagasaka, Yiwei Li, Amro Aboukameel, Md Hafiz Uddin, Mohammed Najeeb Al-Hallak

Cancer Res Commun· May 2022

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PAK4-NAMPT Dual Inhibition Sensitizes Pancreatic Neuroendocrine Tumors to Everolimus.
Gabriel B Mpilla, Md Hafiz Uddin, Mohammed N Al-Hallak, Amro Aboukameel, Yiwei Li

Mol Cancer Ther· October 2021

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Impact of XPO1 mutations on survival outcomes in metastatic non-small cell lung cancer (NSCLC).
Misako Nagasaka, Mohammad Fahad B Asad, Mohammed Najeeb Al Hallak, Md Hafiz Uddin, Ammar Sukari

Lung Cancer· October 2021

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Spotlight on Trastuzumab Deruxtecan (DS-8201,T-DXd) for Mutation Positive Non-Small Cell Lung Cancer.
Ibrahim Azar, Samer Alkassis, Jami Fukui, Fares Alsawah, Kalub Fedak, Mohammed Najeeb Al Hallak

Lung Cancer (Auckl)· October 2021

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Targeting KRAS in pancreatic cancer: new drugs on the horizon.
Sahar F Bannoura, Md Hafiz Uddin, Misako Nagasaka, Farzeen Fazili, Mohammed Najeeb Al-Hallak

Cancer Metastasis Rev· September 2021

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Non-Coding RNAs in Pancreatic Cancer Diagnostics and Therapy: Focus on lncRNAs, circRNAs, and piRNAs.
Yiwei Li, Mohammed Najeeb Al Hallak, Philip A Philip, Asfar S Azmi, Ramzi M Mohammad

Cancers (Basel)· August 2021

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Gastrointestinal stromal tumor: a review of current and emerging therapies.
Bayan Al-Share, Abdulrahman Alloghbi, Mohammed Najeeb Al Hallak, Hafiz Uddin, Asfar Azmi

Cancer Metastasis Rev· June 2021

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Liquid biopsy for therapy monitoring in early-stage non-small cell lung cancer.
Misako Nagasaka, Mohammed Hafiz Uddin, Mohammed Najeeb Al-Hallak, Sarah Rahman, Suresh Balasubramanian

Mol Cancer· June 2021

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Exosomal microRNA in Pancreatic Cancer Diagnosis, Prognosis, and Treatment: From Bench to Bedside.
Md Hafiz Uddin, Mohammed Najeeb Al-Hallak, Philip A Philip, Ramzi M Mohammad, Nerissa Viola

Cancers (Basel)· June 2021

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Gastric cancer: a comprehensive review of current and future treatment strategies.
Rachel E Sexton, Mohammed Najeeb Al Hallak, Maria Diab, Asfar S Azmi

Cancer Metastasis Rev· December 2020

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Calcium Release-Activated Calcium (CRAC) Channel Inhibition Suppresses Pancreatic Ductal Adenocarcinoma Cell Proliferation and Patient-Derived Tumor Growth.
Husain Yar Khan, Gabriel B Mpilla, Rachel Sexton, Srikant Viswanadha, Kumar V Penmetsa, Mohammed Najeeb Al-Hallak

Cancers (Basel)· March 2020

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