Publications by authors named "Mong-Jen Chen"

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SERENE ER Analysis Part 1-SERENE CD: Exposure-Response Analysis of Higher Versus Standard Adalimumab Dosing Regimens for Patients With Moderately to Severely Active Crohn Disease.
Mong-Jen Chen, Ana Victoria Ponce-Bobadilla, Sven Stodtmann, Alexandra P Song, Tricia K Finney-Hayward

Clin Pharmacol Drug Dev· September 2024

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SERENE ER Analysis Part 2 SERENE-UC: Exposure-response Analysis of Higher Versus Standard Adalimumab Dosing Regimens for Patients with Moderately to Severely Active Ulcerative Colitis.
Sven Stodtmann, Mong-Jen Chen, Ana Victoria Ponce-Bobadilla, Tricia K Finney-Hayward, Jasmina Kalabic

Clin Pharmacol Drug Dev· September 2024

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Phase 1 study of safety and tolerability of an oral contraceptive containing low-dose ethinyl oestradiol combined with glecaprevir/pibrentasvir treatment in healthy premenopausal women.
Dee-Dee Shiller, Betty B Yao, Mong-Jen Chen, Amelia Orejudos, Nael M Mostafa

J Viral Hepat· July 2024

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Bioequivalence of Elagolix/Estradiol/Norethindrone Acetate Fixed-Dose Combination Product: Phase 1 Results in Healthy Pre- and Postmenopausal Women.
Mong-Jen Chen, Patrick Marroum, Yi-Lin Chiu, Melina Neenan, Nael M Mostafa

Clin Pharmacol Drug Dev· June 2024

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Sensitivity of Pharmacokinetics to Differences in the Particle Size Distribution for Formulations of Locally Acting Mometasone Furoate Suspension-Based Nasal Sprays.
Elham Amini, Simon M Berger, Uta Schilling, Yuanyuan Jiao, Mong-Jen Chen

Mol Pharm· November 2023

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Central and peripheral lung deposition of fluticasone propionate dry powder inhaler formulations in humans characterized by population pharmacokinetics.
Stefanie K Drescher, Yuanyuan Jiao, Mong-Jen Chen, Abhinav Kurumaddali, Jie Shao

Pharm Res· May 2023

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Assessing the Impact of Immunogenicity and Improving Prediction of Trough Concentrations: Population Pharmacokinetic Modeling of Adalimumab in Patients with Crohn's Disease and Ulcerative Colitis.
Ana Victoria Ponce-Bobadilla, Sven Stodtmann, Mong-Jen Chen, Insa Winzenborg, Sven Mensing

Clin Pharmacokinet· April 2023

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Virtual Bioequivalence Assessment of Elagolix Formulations Using Physiologically Based Pharmacokinetic Modeling.
Dwaipayan Mukherjee, Mong-Jen Chen, Xi Shao, Tzuchi R Ju, Mohamad Shebley

AAPS J· March 2023

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Bridging Fixed Dose to Body Weight-based Regimen of Adalimumab in Paediatric Ulcerative Colitis Using a Pharmacometric Modelling Approach: Case Study with the Phase 3 ENVISION I Trial.
Sven Stodtmann, Mong-Jen Chen, Lucia Siovitz, Mareike Bereswill, Andreas Lazar

J Crohns Colitis· November 2022

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Correction to: Can Pharmacokinetic Studies Assess the Pulmonary Fate of Dry Powder Inhaler Formulations of Fluticasone Propionate?
Günther Hochhaus, Mong-Jen Chen, Abhinav Kurumaddali, Uta Schilling, Yuanyuan Jiao

AAPS J· November 2021

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Can Pharmacokinetic Studies Assess the Pulmonary Fate of Dry Powder Inhaler Formulations of Fluticasone Propionate?
Günther Hochhaus, Mong-Jen Chen, Abhinav Kurumaddali, Uta Schilling, Yuanyuan Jiao

AAPS J· March 2021

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Alpha-1-Antitrypsin Ameliorates Pristane Induced Diffuse Alveolar Hemorrhage in Mice.
Ahmed S Elshikha, Georges Abboud, Lonneke van der Meijden-Erkelens, Yuanqing Lu, Mong-Jen Chen

J Clin Med· August 2019

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Comparable Efficacy and Better Safety of Double β-Lactam Combination Therapy versus β‑Lactam plus Aminoglycoside in Gram-Negative Bacteria in Randomized, Controlled Trials.
Yuanyuan Jiao, Bartolome Moya, Mong-Jen Chen, Alexandre P Zavascki, Hsinyin Tsai

Antimicrob Agents Chemother· July 2019

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Pharmacokinetic and pharmacodynamic modeling of gut hormone peptide YY after pulmonary delivery.
Jie Shao, Mong-Jen Chen, Philip J Kuehl, Guenther Hochhaus

Drug Dev Ind Pharm· July 2019

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Fetal Concentrations of Budesonide and Fluticasone Propionate: a Study in Mice.
Syedsaoud Zaidi, Mong-Jen Chen, Daniel T Lee, Elsa Neubart, Pär Ewing

AAPS J· April 2019

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Effects of lipid formulations on clove extract spray dried powders: comparison of physicochemical properties, storage stability and in vitro intestinal permeation.
Diego F Cortes-Rojas, Claudia R F Souza, Mong-Jen Chen, Guenther Hochhaus, Wanderley P Oliveira

Pharm Dev Technol· December 2018

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Alpha 1 Antitrypsin Gene Therapy Extends the Lifespan of Lupus-Prone Mice.
Ahmed Samir Elshikha, Ye Yuan, Yuanqing Lu, Mong-Jen Chen, Georges Abboud

Mol Ther Methods Clin Dev· December 2018

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Predicting Pulmonary Pharmacokinetics from In Vitro Properties of Dry Powder Inhalers.
Sharvari Bhagwat, Uta Schilling, Mong-Jen Chen, Xiangyin Wei, Renishkumar Delvadia

Pharm Res· December 2017

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Alpha 1 Antitrypsin Inhibits Dendritic Cell Activation and Attenuates Nephritis in a Mouse Model of Lupus.
Ahmed S Elshikha, Yuanqing Lu, Mong-Jen Chen, Mohammad Akbar, Leilani Zeumer

PLoS One· July 2017

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Alpha-1 antitrypsin inhibits RANKL-induced osteoclast formation and functions.
Mohammad Ahsanul Akbar, David Nardo, Mong-Jen Chen, Ahmed S Elshikha, Rubina Ahamed

Mol Med· May 2017

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Transplantation of Adipose Tissue-Derived Mesenchymal Stem Cell (ATMSC) Expressing Alpha-1 Antitrypsin Reduces Bone Loss in Ovariectomized Osteoporosis Mice.
Mohammad Ahsanul Akbar, Yuanqing Lu, Ahmed S Elshikha, Mong-Jen Chen, Ye Yuan

Hum Gene Ther· February 2017

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Alpha-1 Antitrypsin Gene Therapy Ameliorates Bone Loss in Ovariectomy-Induced Osteoporosis Mouse Model.
Mohammad Ahsanul Akbar, Jay J Cao, Yuanqing Lu, David Nardo, Mong-Jen Chen

Hum Gene Ther· September 2016

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In Situ Transplantation of Alginate Bioencapsulated Adipose Tissues Derived Stem Cells (ADSCs) via Hepatic Injection in a Mouse Model.
Mong-Jen Chen, Yuanqing Lu, Nicholas E Simpson, Mark J Beveridge, Ahmed S Elshikha, Tina Chen

PLoS One· May 2016

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Reprogramming adipose tissue-derived mesenchymal stem cells into pluripotent stem cells by a mutant adeno-associated viral vector.
Mong-Jen Chen, Yuanqing Lu, Takashi Hamazaki, Hsin-Yin Tsai, Kirsten Erger

Hum Gene Ther Methods· February 2014

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Microsatellite in the 3' untranslated region of human fibroblast growth factor 9 (FGF9) gene exhibits pleiotropic effect on modulating FGF9 protein expression.
Tsung-Ming Chen, Pao-Lin Kuo, Chien-Hui Hsu, Shaw-Jenq Tsai, Mong-Jen Chen

Hum Mutat· January 2007

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