Publications by authors named "Mordechai Choder"

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Proper 5'-3' cotranslational mRNA decay in yeast requires import of Xrn1 to the nucleus.
Antonio Jordán-Pla, Yujie Zhang, José García-Martínez, Shiladitya Chattopadhyay, Anabel Forte, Mordechai Choder

PLoS One· May 2025

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The zinc-finger transcription factor Sfp1 imprints specific classes of mRNAs and links their synthesis to cytoplasmic decay.
Moran Kelbert, Antonio Jordán-Pla, Lola de Miguel-Jiménez, José García-Martínez, Michael Selitrennik, Mordechai Choder

Elife· October 2024

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Comparison of Xrn1 and Rat1 5' → 3' exoribonucleases in budding yeast supports the specific role of Xrn1 in cotranslational mRNA decay.
José E Pérez-Ortín, Antonio Jordán-Pla, Yujie Zhang, Jorge Moreno-García, Claudio Bassot, Mordechai Choder

Yeast· July 2024

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RNA-controlled nucleocytoplasmic shuttling of mRNA decay factors regulates mRNA synthesis and a novel mRNA decay pathway.
Shiladitya Chattopadhyay, Jose Garcia-Martinez, Gal Haimovich, Jonathan Fischer, Aya Khwaja, Mordechai Choder

Nat Commun· November 2022

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Numerous Post-translational Modifications of RNA Polymerase II Subunit Rpb4/7 Link Transcription to Post-transcriptional Mechanisms.
Stephen Richard, Lital Gross, Jonathan Fischer, Keren Bendalak, Tamar Ziv, Mordechai Choder

Cell Rep· January 2021

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The yeast exoribonuclease Xrn1 and associated factors modulate RNA polymerase II processivity in 5' and 3' gene regions.
Jonathan Fischer, Yun S Song, Nir Yosef, Julia di Iulio, L Stirling Churchman, Mordechai Choder

J Biol Chem· August 2020

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Dissociation of Rpb4 from RNA polymerase II is important for yeast functionality.
Lea Duek, Oren Barkai, Ron Elran, Isra Adawi, Mordechai Choder

PLoS One· April 2019

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The exonuclease Xrn1 activates transcription and translation of mRNAs encoding membrane proteins.
Bernat Blasco-Moreno, Leire de Campos-Mata, René Böttcher, José García-Martínez, Jennifer Jungfleisch, Mordechai Choder

Nat Commun· March 2019

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Conceptual modeling of mRNA decay provokes new hypotheses.
Judith Somekh, Gal Haimovich, Adi Guterman, Dov Dori, Mordechai Choder

PLoS One· June 2015

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Pheromone-encoding mRNA is transported to the yeast mating projection by specific RNP granules.
Stella Aronov, Saray Dover-Biterman, Edith Suss-Toby, Michael Shmoish, Lea Duek, Mordechai Choder

J Cell Biol· June 2015

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Cytoplasmic 5'-3' exonuclease Xrn1p is also a genome-wide transcription factor in yeast.
Daniel A Medina, Antonio Jordán-Pla, Gonzalo Millán-Zambrano, Sebastián Chávez, Mordechai Choder

Front Genet· February 2014

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Eukaryotic mRNA decay: methodologies, pathways, and links to other stages of gene expression.
José E Pérez-Ortín, Paula Alepuz, Sebastián Chávez, Mordechai Choder

J Mol Biol· October 2013

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The fate of the messenger is pre-determined: a new model for regulation of gene expression.
Gal Haimovich, Mordechai Choder, Robert H Singer, Tatjana Trcek

Biochim Biophys Acta· August 2013

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Gene expression is circular: factors for mRNA degradation also foster mRNA synthesis.
Gal Haimovich, Daniel A Medina, Sebastien Z Causse, Manuel Garber, Gonzalo Millán-Zambrano, Mordechai Choder

Cell· May 2013

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The eukaryotic transcriptional machinery regulates mRNA translation and decay in the cytoplasm.
Nili Dahan, Mordechai Choder

Biochim Biophys Acta· January 2013

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Conceptual Model-based Systems Biology: mapping knowledge and discovering gaps in the mRNA transcription cycle.
Judith Somekh, Mordechai Choder, Dov Dori

PLoS One· December 2012

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Promoter elements regulate cytoplasmic mRNA decay.
Almog Bregman, Moran Avraham-Kelbert, Oren Barkai, Lea Duek, Adi Guterman, Mordechai Choder

Cell· December 2011

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Transcriptome kinetics is governed by a genome-wide coupling of mRNA production and degradation: a role for RNA Pol II.
Ophir Shalem, Bella Groisman, Mordechai Choder, Orna Dahan, Yitzhak Pilpel

PLoS Genet· September 2011

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mRNA imprinting: Additional level in the regulation of gene expression.
Mordechai Choder

Cell Logist· January 2011

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RNA polymerase II subunits link transcription and mRNA decay to translation.
Liat Harel-Sharvit, Naama Eldad, Gal Haimovich, Oren Barkai, Lea Duek, Mordechai Choder

Cell· November 2010

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Transcription in the nucleus and mRNA decay in the cytoplasm are coupled processes.
Vicky Goler-Baron, Michael Selitrennik, Oren Barkai, Gal Haimovich, Rona Lotan, Mordechai Choder

Genes Dev· August 2008

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Alopecia, neurological defects, and endocrinopathy syndrome caused by decreased expression of RBM28, a nucleolar protein associated with ribosome biogenesis.
Janna Nousbeck, Ronen Spiegel, Akemi Ishida-Yamamoto, Margarita Indelman, Ayelet Shani-Adir, Mordechai Choder

Am J Hum Genet· May 2008

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SERKAL syndrome: an autosomal-recessive disorder caused by a loss-of-function mutation in WNT4.
Hannah Mandel, Revital Shemer, Zvi U Borochowitz, Marina Okopnik, Carlos Knopf, Mordechai Choder

Am J Hum Genet· January 2008

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Conceptual modeling in systems biology fosters empirical findings: the mRNA lifecycle.
Dov Dori, Mordechai Choder

PLoS One· September 2007

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The Rpb7p subunit of yeast RNA polymerase II plays roles in the two major cytoplasmic mRNA decay mechanisms.
Rona Lotan, Vicky Goler-Baron, Lea Duek, Gal Haimovich, Mordechai Choder

J Cell Biol· September 2007

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