Publications by authors named "Morgan E Desantis"

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Distinct dynein complexes defined by DYNLRB1 and DYNLRB2 regulate mitotic and male meiotic spindle bipolarity.
Shuwen He, John P Gillies, Juliana L Zang, Carmen M Córdoba-Beldad, Io Yamamoto, Yasuhiro Fujiwara, Julie Grantham, Morgan E DeSantis, Hiroki Shibuya

Nat Commun· March 2023

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Occludin acts as a dynein adaptor regulating permeability and collateral angiogenesis.
Xuwen Liu, Enming J Su, Alyssa Dreffs, John P Gillies, Madeline Merlino, Morgan E DeSantis

Proc Natl Acad Sci U S A· December 2025

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CCSer2 gates dynein activity at the cell periphery.
Juliana L Zang, Daytan Gibson, Ann-Marie Zheng, Wanjing Shi, John P Gillies, Morgan E DeSantis

J Cell Biol· June 2025

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Synthetic cargo adaptors reveal molecular features that can enhance dynein activation.
Aravintha Siva, John P Gillies, Ashley de Borchgrave, Sharon R Garrott, Rishi Mishra, Morgan E DeSantis

bioRxiv· June 2025

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HIV-1 binds dynein directly to hijack microtubule transport machinery.
Somayesadat Badieyan, Drew Lichon, Sevnur Komurlu Keceli, Michael P Andreas, John P Gillies, Morgan E DeSantis

Sci Adv· June 2025

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Occludin Acts as a Dynein Adaptor Regulating Permeability and Collateral Angiogenesis.
Xuwen Liu, Enming J Su, Alyssa Dreffs, John P Gillies, Madeline Merlino, Morgan E DeSantis

bioRxiv· June 2025

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Cargo adaptor identity controls the mechanism and kinetics of dynein activation.
John P Gillies, Saffron R Little, Aravintha Siva, William O Hancock, Morgan E DeSantis

J Biol Chem· April 2025

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Cargo adaptor identity controls the mechanism and kinetics of dynein activation.
John P Gillies, Saffron R Little, William O Hancock, Morgan E DeSantis

bioRxiv· October 2024

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CCSer2 gates dynein activity at the cell periphery.
Juliana L Zang, Daytan Gibson, Ann-Marie Zheng, Wanjing Shi, John P Gillies, Morgan E DeSantis

bioRxiv· June 2024

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HIV-1 binds dynein directly to hijack microtubule transport machinery.
Somayesadat Badieyan, Drew Lichon, Michael P Andreas, John P Gillies, Wang Peng, Morgan E DeSantis

bioRxiv· December 2023

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Ndel1 disfavors dynein-dynactin-adaptor complex formation in two distinct ways.
Sharon R Garrott, John P Gillies, Aravintha Siva, Saffron R Little, Rita El Jbeily, Morgan E DeSantis

J Biol Chem· June 2023

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CryoEM shows the active dynein complex on microtubules.
Sharon R Garrott, Morgan E DeSantis

Trends Biochem Sci· April 2023

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Structures of human dynein in complex with the lissencephaly 1 protein, LIS1.
Janice M Reimer, Morgan E DeSantis, Samara L Reck-Peterson, Andres E Leschziner

Elife· January 2023

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Ndel1 modulates dynein activation in two distinct ways.
Sharon R Garrott, John P Gillies, Aravintha Siva, Saffron R Little, Rita Ei Jbeily, Morgan E DeSantis

bioRxiv· January 2023

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The KASH5 protein involved in meiotic chromosomal movements is a novel dynein activating adaptor.
Ritvija Agrawal, John P Gillies, Juliana L Zang, Jingjing Zhang, Sharon R Garrott, Morgan E DeSantis

Elife· June 2022

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Nde1 and Ndel1: Outstanding Mysteries in Dynein-Mediated Transport.
Sharon R Garrott, John P Gillies, Morgan E DeSantis

Front Cell Dev Biol· April 2022

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Self-repair protects microtubules from destruction by molecular motors.
Sarah Triclin, Daisuke Inoue, Jérémie Gaillard, Zaw Min Htet, Morgan E DeSantis

Nat Mater· June 2021

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LIS1 promotes the formation of activated cytoplasmic dynein-1 complexes.
Zaw Min Htet, John P Gillies, Richard W Baker, Andres E Leschziner, Morgan E DeSantis

Nat Cell Biol· May 2020

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Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains.
Lin Guo, Hong Joo Kim, Hejia Wang, John Monaghan, Fernande Freyermuth, Morgan E DeSantis

Cell· April 2018

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Lis1 Has Two Opposing Modes of Regulating Cytoplasmic Dynein.
Morgan E DeSantis, Michael A Cianfrocco, Zaw Min Htet, Phuoc Tien Tran, Samara L Reck-Peterson

Cell· September 2017

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The human cytoplasmic dynein interactome reveals novel activators of motility.
William B Redwine, Morgan E DeSantis, Ian Hollyer, Zaw Min Htet, Phuoc Tien Tran

Elife· July 2017

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Mechanism and regulation of cytoplasmic dynein.
Michael A Cianfrocco, Morgan E DeSantis, Andres E Leschziner, Samara L Reck-Peterson

Annu Rev Cell Dev Biol· September 2016

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The Hsp104 N-terminal domain enables disaggregase plasticity and potentiation.
Elizabeth A Sweeny, Meredith E Jackrel, Michelle S Go, Matthew A Sochor, Beatrice M Razzo, Morgan E DeSantis

Mol Cell· March 2015

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Conserved distal loop residues in the Hsp104 and ClpB middle domain contact nucleotide-binding domain 2 and enable Hsp70-dependent protein disaggregation.
Morgan E Desantis, Elizabeth A Sweeny, David Snead, Eunice H Leung, Michelle S Go

J Biol Chem· January 2014

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Potentiated Hsp104 variants antagonize diverse proteotoxic misfolding events.
Meredith E Jackrel, Morgan E DeSantis, Bryan A Martinez, Laura M Castellano, Rachel M Stewart

Cell· January 2014

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