Publications by authors named "Moritake Higa"

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Unequal distribution of plasma glucagon levels among clustering-based diabetes subtypes: a Japanese cohort.
Hayato Tanabe, Yoshinori Shimajiri, Kaori Shiroma, Moritake Higa, Hiroaki Masuzaki

J Clin Endocrinol Metab· December 2025

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Young-onset type 2 diabetes mellitus enhances proteinuria, but not glomerular filtration rate decline: A Japanese cohort study.
Haruka Saito, Hayato Tanabe, Hiroyuki Hirai, Moritake Higa, Kenichi Tanaka

J Diabetes Investig· October 2024

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Circulating microRNA profile of long-lived Okinawans identifies novel potential targets for optimizing lifespan and health span.
Sarah Noureddine, Augusto Schneider, Sydney Strader, Xiang Zhu, Joseph Dhahbi, Moritake Higa

Aging Cell· August 2024

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Impact of treatment cessation on incidence and progression of retinopathy in Japanese patients with type 2 diabetes mellitus: a retrospective cohort study.
Yukiko Shinzato, Yoshiro Nakayama, Shiki Okamoto, Jasmine F Millman, Tsugumi Uema, Moritake Higa

Diabetol Int· July 2024

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Novel protective effect of the FOXO3 longevity genotype on mechanisms of cellular aging in Okinawans.
Trevor H Torigoe, D Craig Willcox, Michio Shimabukuro, Moritake Higa, Mariana Gerschenson

NPJ Aging· March 2024

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Role of perirenal adiposity in renal dysfunction among CKD individuals with or without diabetes: a Japanese cross-sectional study.
Teruyuki Kono, Gulinu Maimaituxun, Hayato Tanabe, Moritake Higa, Haruka Saito

BMJ Open Diabetes Res Care· March 2024

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Effect of dapagliflozin on 24-hour glycemic variables in Japanese patients with type 2 diabetes mellitus receiving basal insulin supported oral therapy (DBOT): a multicenter, randomized, open-label, parallel-group study.
Akihiro Kudo, Noritaka Machii, Toshio Ono, Haruka Saito, Yoshito Oshiro, Moritake Higa

BMJ Open Diabetes Res Care· April 2023

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Risk Classification for Metabolic Syndrome and the Incidence of Cardiovascular Disease in Japan With Low Prevalence of Obesity: A Pooled Analysis of 10 Prospective Cohort Studies.
Hiroyasu Iso, Renzhe Cui, Iseki Takamoto, Masahiko Kiyama, Isao Saito, Aya Higashiyama, Moritake Higa

J Am Heart Assoc· December 2021

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Retrospective exploratory analyses on gender differences in determinants for incidence and progression of diabetic retinopathy in Japanese patients with type 2 diabetes mellitus.
Yoshiro Nakayama, Satoshi Yamaguchi, Yukiko Shinzato, Shiki Okamoto, Jasmine F Millman, Moritake Higa

Endocr J· June 2021

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High FIB4 index is an independent risk factor of diabetic kidney disease in type 2 diabetes.
Haruka Saito, Hayato Tanabe, Akihiro Kudo, Noritaka Machii, Moritake Higa

Sci Rep· June 2021

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Regional Variations of Insulin Secretion and Insulin Sensitivity in Japanese Participants With Normal Glucose Tolerance.
Kiriko Watanabe, Moritake Higa, Yoshimasa Hasegawa, Akihiro Kudo, Richard C Allsopp

Front Nutr· March 2021

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Novel STAR gene variant in a patient with classic lipoid congenital adrenal hyperplasia and combined pituitary hormone deficiency.
Moritake Higa, Akiko Zaha, Akiko Takushi, Nami Morishima, Toyofumi Majikina

Hum Genome Var· February 2021

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Age-Dependent Efficacy of Ezetimibe for Low-Density Lipoprotein Cholesterol Reduction in Japanese Patients with or without Type 2 Diabetes Mellitus.
Satoshi Yamaguchi, Kageyuki Oba, Moritake Higa, Osamu Arasaki, Michio Shimabukuro

J Clin Med· June 2020

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Dissimilar Effects of Anagliptin and Sitagliptin on Lipoprotein Subclass in Standard or Strong Statin-Treated Patients with Type-2 Diabetes Mellitus: A Subanalysis of the REASON (Randomized Evaluation of Anagliptin versus Sitagliptin on Low-Density LipoproteiN Cholesterol in Diabetes) Trial.
Hiroyuki Hirai, Moritake Higa, Takeshi Morimoto, Mio Sakuma, Osamu Arasaki

J Clin Med· December 2019

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Minimal Shortening of Leukocyte Telomere Length Across Age Groups in a Cross-Sectional Study for Carriers of a Longevity-Associated FOXO3 Allele.
Philip M C Davy, D Craig Willcox, Michio Shimabukuro, Timothy A Donlon, Trevor Torigoe, Moritake Higa

J Gerontol A Biol Sci Med Sci· October 2018

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A novel insulinotropic mechanism of whole grain-derived γ-oryzanol via the suppression of local dopamine D receptor signalling in mouse islet.
Chisayo Kozuka, Sumito Sunagawa, Rei Ueda, Moritake Higa, Yuzuru Ohshiro

Br J Pharmacol· September 2015

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Subclinical Carotid Atherosclerosis Burden in the Japanese: Comparison between Okinawa and Nagano Residents.
Michio Shimabukuro, Yoshimasa Hasegawa, Moritake Higa, Rie Amano, Hirotsugu Yamada

J Atheroscler Thromb· August 2015

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γ-Oryzanol protects pancreatic β-cells against endoplasmic reticulum stress in male mice.
Chisayo Kozuka, Sumito Sunagawa, Rei Ueda, Moritake Higa, Hideaki Tanaka

Endocrinology· April 2015

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Lipid deposition in various sites of the skeletal muscles and liver exhibits a positive correlation with visceral fat accumulation in middle-aged Japanese men with metabolic syndrome.
Shin-ichiro Taira, Michio Shimabukuro, Moritake Higa, Kouichi Yabiku, Chisayo Kozuka

Intern Med· March 2014

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Ectopic fat deposition and global cardiometabolic risk: new paradigm in cardiovascular medicine.
Michio Shimabukuro, Chisayo Kozuka, Shin-ichiro Taira, Koichi Yabiku, Munkhbaatar Dagvasumberel, Moritake Higa

J Med Invest· January 2014

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Effects of the brown rice diet on visceral obesity and endothelial function: the BRAVO study.
Michio Shimabukuro, Moritake Higa, Rie Kinjo, Ken Yamakawa, Hideaki Tanaka

Br J Nutr· January 2014

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Miglitol, α-glycosidase inhibitor, reduces visceral fat accumulation and cardiovascular risk factors in subjects with the metabolic syndrome: a randomized comparable study.
Michio Shimabukuro, Moritake Higa, Ken Yamakawa, Hiroaki Masuzaki, Masataka Sata

Int J Cardiol· September 2013

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Eicosapentaenoic Acid supplementation changes Fatty Acid composition and corrects endothelial dysfunction in hyperlipidemic patients.
Ken Yamakawa, Michio Shimabukuro, Namio Higa, Tomohiro Asahi, Kageyuki Ohba, Moritake Higa, Tohru Higa

Cardiol Res Pract· January 2013

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Brown rice and its component, γ-oryzanol, attenuate the preference for high-fat diet by decreasing hypothalamic endoplasmic reticulum stress in mice.
Chisayo Kozuka, Kouichi Yabiku, Sumito Sunagawa, Rei Ueda, Shin-Ichiro Taira, Moritake Higa

Diabetes· December 2012

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Single-incision laparoscopic adrenalectomy for primary aldosteronism: report of a case.
Masamori Shimabuku, Akira Sasaki, Moritake Higa, Masanori Kakazu, Masaya Asato

Surg Today· September 2011

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