Publications by authors named "Moritz Spiske"

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Linker Modification Enables Control of Key Functional Group Orientation in Macrocycles.
Christian Brudy, Enrico Ruijsenaars, Christian Meyners, Wisely O Sugiarto, Hanaa Achaq, Moritz Spiske

J Med Chem· December 2025

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Conformational Plasticity and Binding Affinity Enhancement Controlled by Linker Derivatization in Macrocycles.
Vanessa Buffa, Carlo Walz, Christian Meyners, Min Zheng, Wisely Oki Sugiarto, Moritz Spiske

Angew Chem Int Ed Engl· March 2025

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Conformationally Restricted Macrocycles as Improved FKBP51 Inhibitors Enabled by Systematic Linker Derivatization.
Moritz Spiske, Christian Meyners, Michael Bauder, Maximilian Repity, Christian Brudy

Angew Chem Int Ed Engl· March 2025

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Macrocyclization as a Strategy for Kinetic Solubility Improvement: A Comparative Analysis of Matched Molecular Pairs.
Carlo Walz, Moritz Spiske, Magnus Walter, Benjamin-Luca Keller, Mario Mezler

J Med Chem· February 2025

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The Missing Link(er): A Roadmap to Macrocyclization in Drug Discovery.
Christian Brudy, Carlo Walz, Moritz Spiske, Johannes K Dreizler, Felix Hausch

J Med Chem· September 2024

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