Publications by authors named "Muhammad Akhtar Ali"

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Large-scale genomic investigation of pediatric cholestasis reveals a novel hepatorenal ciliopathy caused by PSKH1 mutations.
Sateesh Maddirevula, Mohammad Shagrani, Ae-Ri Ji, Christopher R Horne, Samuel N Young, Ali Syed Muhammad Akhtar

Genet Med· November 2024

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Identification of RdRp inhibitors against SARS-CoV-2 through E-pharmacophore-based virtual screening, molecular docking and MD simulations approaches.
Hafiz Muzzammel Rehman, Muhammad Sajjad, Muhammad Akhtar Ali, Roquyya Gul, Muhammad Naveed

Int J Biol Macromol· May 2023

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Identification of NS2B-NS3 Protease Inhibitors for Therapeutic Application in ZIKV Infection: A Pharmacophore-Based High-Throughput Virtual Screening and MD Simulations Approaches.
Hafiz Muzzammel Rehman, Muhammad Sajjad, Muhammad Akhtar Ali, Roquyya Gul, Muhammad Irfan

Vaccines (Basel)· January 2023

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Correction: Computational investigation of the increased virulence and pathogenesis of SARS-CoV-2 lineage B.1.1.7.
N Arul Murugan, Prashanth S Javali, Chitra Jeyaraj Pandianb, Muhammad Akhtar Ali, Vaibhav Srivastava

Phys Chem Chem Phys· November 2022

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Computational investigation of the increased virulence and pathogenesis of SARS-CoV-2 lineage B.1.1.7.
N Arul Murugan, Prashanth S Javali, Chitra Jeyaraj Pandianb, Muhammad Akhtar Ali, Vaibhav Srivastava

Phys Chem Chem Phys· August 2022

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Monoallelic and bi-allelic variants in NCDN cause neurodevelopmental delay, intellectual disability, and epilepsy.
Ambrin Fatima, Jan Hoeber, Jens Schuster, Eriko Koshimizu, Carolina Maya-Gonzalez, Talia Akram, Zafar Ali, Muhammad Akhtar Ali

Am J Hum Genet· March 2022

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Common and mutation specific phenotypes of KRAS and BRAF mutations in colorectal cancer cells revealed by integrative -omics analysis.
Snehangshu Kundu, Muhammad Akhtar Ali, Niklas Handin, Louis P Conway, Veronica Rendo

J Exp Clin Cancer Res· July 2021

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Monoallelic and bi-allelic variants in NCDN cause neurodevelopmental delay, intellectual disability, and epilepsy.
Ambrin Fatima, Jan Hoeber, Jens Schuster, Eriko Koshimizu, Carolina Maya-Gonzalez, Talia Akram, Zafar Ali, Muhammad Akhtar Ali

Am J Hum Genet· April 2021

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The Therapeutic Prospects of Naturally Occurring and Synthetic Indole Alkaloids for Depression and Anxiety Disorders.
Samman Munir, Aqsa Shahid, Bilal Aslam, Usman Ali Ashfaq, Muhammad Sajid Hamid Akash, Muhammad Akhtar Ali

Evid Based Complement Alternat Med· October 2020

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SHISA3, an antagonist of the Wnt/β-catenin signaling, is epigenetically silenced and its ectopic expression suppresses growth in breast cancer.
Naveed Shahzad, Tehreem Munir, Mariam Javed, Fareeda Tasneem, Bilal Aslam, Moazzam Ali, Muhammad Akhtar Ali

PLoS One· September 2020

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Sequence Types Harboring Genes Encoding Aminoglycoside Modifying Enzymes and 16SrRNA Methylase; a Multicenter Study from Pakistan.
Mohsin Khurshid, Muhammad Hidayat Rasool, Usman Ali Ashfaq, Bilal Aslam, Muhammad Waseem, Muhammad Akhtar Ali

Infect Drug Resist· August 2020

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Restoration of KMT2C/MLL3 in human colorectal cancer cells reinforces genome-wide H3K4me1 profiles and influences cell growth and gene expression.
Chatarina Larsson, Lina Cordeddu, Lee Siggens, Tatjana Pandzic, Snehangshu Kundu, Muhammad Akhtar Ali

Clin Epigenetics· May 2020

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Linking FOXO3, NCOA3, and TCF7L2 to Ras pathway phenotypes through a genome-wide forward genetic screen in human colorectal cancer cells.
Snehangshu Kundu, Muhammad Akhtar Ali, Niklas Handin, Narendra Padhan, Jimmy Larsson

Genome Med· January 2018

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Somatic c.4467delA mutations in colorectal cancers control histone methylation and tumor growth.
Tatjana Pandzic, Veronica Rendo, Jinyeong Lim, Chatarina Larsson, Jimmy Larsson, Muhammad Akhtar Ali

Oncotarget· November 2017

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Loss of DIP2C in RKO cells stimulates changes in DNA methylation and epithelial-mesenchymal transition.
Chatarina Larsson, Muhammad Akhtar Ali, Tatjana Pandzic, Anders M Lindroth, Liqun He

BMC Cancer· July 2017

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Transposon Mutagenesis Reveals Fludarabine Resistance Mechanisms in Chronic Lymphocytic Leukemia.
Tatjana Pandzic, Jimmy Larsson, Liqun He, Snehangshu Kundu, Kenneth Ban, Muhammad Akhtar-Ali

Clin Cancer Res· December 2016

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Transcriptional modulator ZBED6 affects cell cycle and growth of human colorectal cancer cells.
Muhammad Akhtar Ali, Shady Younis, Ola Wallerman, Rajesh Gupta, Leif Andersson

Proc Natl Acad Sci U S A· June 2015

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Computational and molecular tools for scalable rAAV-mediated genome editing.
Ivaylo Stoimenov, Muhammad Akhtar Ali, Tatjana Pandzic, Tobias Sjöblom

Nucleic Acids Res· March 2015

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In situ sequencing identifies TMPRSS2-ERG fusion transcripts, somatic point mutations and gene expression levels in prostate cancers.
Sara Kiflemariam, Marco Mignardi, Muhammad Akhtar Ali, Anders Bergh, Mats Nilsson

J Pathol· October 2014

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Molecular pathways in tumor progression: from discovery to functional understanding.
Muhammad Akhtar Ali, Tobias Sjöblom

Mol Biosyst· September 2009

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