Publications by authors named "Muhammet Ay"

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Neurotoxicants driving glial aging: role of astrocytic aging in non-cell autonomous neurodegeneration.
Pablo Reina-Gonzalez, Muhammet Ay, Monica Langley, Elizabeth Plunk, Rachel Strazdins

Toxicol Sci· September 2025

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Rationally Designed PKD1 Activator Protects Against Neurodegeneration in Pre-clinical Models of Parkinson's Disease.
Arunkumar Asaithambi, Ahyoung Jang, Anamitra Ghosh, Muhammet Ay, Huajun Jin

bioRxiv· February 2025

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Comparative Proteomics Highlights that GenX Exposure Leads to Metabolic Defects and Inflammation in Astrocytes.
Abdulla Abu-Salah, Müberra Fatma Cesur, Aiesha Anchan, Muhammet Ay, Monica R Langley

Environ Sci Technol· November 2024

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Seminar: Functional Exposomics and Mechanisms of Toxicity-Insights from Model Systems and NAMs.
Yunjia Lai, Muhammet Ay, Carolina Duarte Hospital, Gary W Miller, Souvarish Sarkar

Environ Health Perspect· September 2024

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Mito-metformin protects against mitochondrial dysfunction and dopaminergic neuronal degeneration by activating upstream PKD1 signaling in cell culture and MitoPark animal models of Parkinson's disease.
Muhammet Ay, Adhithiya Charli, Monica Langley, Ahyoung Jang, Piyush Padhi

Front Neurosci· February 2024

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Evaluation of fisetin as a potential inducer of mitochondrial biogenesis in SH-SY5Y neuronal cells.
Muhammet Ay

Iran J Basic Med Sci· January 2023

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Vanillic acid induces mitochondrial biogenesis in SH-SY5Y cells.
Muhammet Ay

Mol Biol Rep· June 2022

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Characterization of nonmotor behavioral impairments and their neurochemical mechanisms in the MitoPark mouse model of progressive neurodegeneration in Parkinson's disease.
Monica R Langley, Shivani Ghaisas, Bharathi N Palanisamy, Muhammet Ay, Huajun Jin

Exp Neurol· July 2021

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Kv1.3 modulates neuroinflammation and neurodegeneration in Parkinson's disease.
Souvarish Sarkar, Hai M Nguyen, Emir Malovic, Jie Luo, Monica Langley, Muhammet Ay, Lee-Way Jin

J Clin Invest· August 2020

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MitoPark transgenic mouse model recapitulates the gastrointestinal dysfunction and gut-microbiome changes of Parkinson's disease.
Shivani Ghaisas, Monica R Langley, Bharathi N Palanisamy, Somak Dutta, Kirthi Narayanaswamy, Muhammet Ay

Neurotoxicology· December 2019

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Manganese exposure exacerbates progressive motor deficits and neurodegeneration in the MitoPark mouse model of Parkinson's disease: Relevance to gene and environment interactions in metal neurotoxicity.
Monica R Langley, Shivani Ghaisas, Muhammet Ay, Jie Luo, Bharathi N Palanisamy

Neurotoxicology· January 2018

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Neurotoxicity of Vanadium.
Hilary Afeseh Ngwa, Muhammet Ay, Huajun Jin, Vellareddy Anantharam, Arthi Kanthasamy

Adv Neurobiol· December 2017

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Mito-Apocynin Prevents Mitochondrial Dysfunction, Microglial Activation, Oxidative Damage, and Progressive Neurodegeneration in MitoPark Transgenic Mice.
Monica Langley, Anamitra Ghosh, Adhithiya Charli, Souvarish Sarkar, Muhammet Ay

Antioxid Redox Signal· November 2017

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Molecular mechanisms underlying protective effects of quercetin against mitochondrial dysfunction and progressive dopaminergic neurodegeneration in cell culture and MitoPark transgenic mouse models of Parkinson's Disease.
Muhammet Ay, Jie Luo, Monica Langley, Huajun Jin, Vellareddy Anantharam

J Neurochem· June 2017

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Molecular cloning, epigenetic regulation, and functional characterization of Prkd1 gene promoter in dopaminergic cell culture models of Parkinson's disease.
Muhammet Ay, Huajun Jin, Dilshan S Harischandra, Arunkumar Asaithambi, Arthi Kanthasamy

J Neurochem· October 2015

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Protein kinase D1 (PKD1) phosphorylation promotes dopaminergic neuronal survival during 6-OHDA-induced oxidative stress.
Arunkumar Asaithambi, Muhammet Ay, Huajun Jin, Anamitra Gosh, Vellareddy Anantharam

PLoS One· June 2015

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