Publications by authors named "Mullangi Ramesh"

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Validation of a Dried Blood Spot Method for the Determination of a Third-Generation Bcr-Abl 1 Inhibitor, Vodobatinib, in Small Volumes of Rat Blood: Application to a Pharmacokinetic Study.
Ashok Zakkula, Keerthana Madipelli, Niranjan Veerla, Rama Murthi Bestha, Sandeep Kaddare, Ramesh Mullangi

Biomed Chromatogr· October 2025

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Validated HPLC-UV Method for the Quantification of a Novel BCr-Abl 1 Inhibitor, Vodobatinib, in Rat Plasma: Application to a Pharmacokinetic Study.
Sandeep Kaddare, Ashok Zakkula, Rama Murthi Bestha, Keerthana Madipelli, Rajnish Kumar, Ramesh Mullangi

Biomed Chromatogr· February 2025

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Highly Sensitive LC-MS/MS Method for Determination of Dexamethasone in Rat Plasma and Brain Tissue: An Application to Pharmacokinetic Study in Rats.
Rama Murthi Bestha, Ashok Zakkula, Madipelli Keerthana, Sandeep Kaddare, Niranjan Veerla, Ramesh Mullangi

Biomed Chromatogr· January 2025

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Validated HPLC-UV method for quantification of paxalisib, a pan PI3K and mTOR inhibitor in mouse plasma: Application to a pharmacokinetic study in mice.
Ashok Zakkula, Harsha K Tripathy, Rama Murthi Bestha, A B Vinod, Vinay Kiran, Ramesh Mullangi

Biomed Chromatogr· April 2023

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Validated LC-MS/MS method for the determination of copanlisib in mouse dried blood spots.
Harsha K Tripathy, Vinay Kiran, Ashok Zakkula, Vinod A B, Rama Murthy Bestha, Ramesh Mullangi

Biomed Chromatogr· February 2023

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Novel tricyclic small molecule inhibitors of Nicotinamide N-methyltransferase for the treatment of metabolic disorders.
Sven Ruf, Sridharan Rajagopal, Sanjay Venkatachalapathi Kadnur, Mahanandeesha S Hallur, Shilpa Rani, Mullangi Ramesh

Sci Rep· September 2022

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Validated liquid chromatography-tandem mass spectrometry method for simultaneous quantitation of bendamustine and copanlisib in mouse plasma: Application to a pharmacokinetic study in mice.
Harsha K Tripathy, S V Nair Manju, Rama Murthy Bestha, Vinay Kiran, Sreekanth Dittakavi, Ramesh Mullangi

Biomed Chromatogr· August 2022

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Pharmacokinetics of Darolutamide in Mouse - Assessment of the Disposition of the Diastereomers, Key Active Metabolite and Interconversion Phenomenon: Implications to Cancer Patients.
Neeraj K Saini, Bhavesh B Gabani, Umesh Todmal, Suresh P Sulochana, Vinay Kiran, Ramesh Mullangi

Drug Metab Lett· January 2022

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Validated HPLC-UV method for simultaneous quantification of phosphatidylinositol 3-kinase inhibitors, copanlisib, duvelisib and idelalisib, in rat plasma: Application to a pharmacokinetic study in rats.
Anup Siddesh, Dhurvu Sriram, Ashok Zakkula, Rajnish Kumar, Sreekanth Dittakavi, Ramesh Mullangi

Biomed Chromatogr· April 2021

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Validated HPLC-MS/MS method for quantitation of AMG 510, a KRAS G12C inhibitor, in mouse plasma and its application to a pharmacokinetic study in mice.
Naveena Madhyastha, Swapan Kumar Samantha, Sreekanth Dittakavi, Meenu Markose, Sadanand Rangnathrao Mallurwar, Ramesh Mullangi

Biomed Chromatogr· April 2021

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Enantioselective in vitro ADME, absolute oral bioavailability, and pharmacokinetics of (-)-lumefantrine and (+)-lumefantrine in mice.
Bhavesh Babulal Gabani, Abhishek Dixit, Vinay Kiran, Ram Murthi Bestha, Balaji Narayanan, Ramesh Mullangi

Xenobiotica· February 2021

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DBS Assay with LC-MS/MS for the Determination of Idelalisib, A Selective PI3K-δ Inhibitor in Mice Blood and Its Application to a Pharmacokinetic Study.
Harsha K Tripathy, Nair S V Manju, Sreekanth Dittakavi, Ashok Zakkula, Ramesh Mullangi

Drug Res (Stuttg)· January 2021

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A concise review of bioanalytical methods of small molecule immuno-oncology drugs in cancer therapy.
Suresh P Sulochana, Ravi Kumar Trivedi, Nuggehally R Srinivas, Ramesh Mullangi

Biomed Chromatogr· January 2021

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A dried blood spot assay with HPLC-MS/MS for the determination of larotrectinib in mouse blood and its application to a pharmacokinetic study.
Harsha K Tripathy, Nair S V Manju, Sreekanth Dittakavi, Ram Murthi Bestha, Ramesh Mullangi

Biomed Chromatogr· December 2020

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A concise review on lipidomics analysis in biological samples.
Ramani Venkata Addepalli, Ramesh Mullangi

ADMET DMPK· December 2020

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Novel methodology to perform incurred sample reanalysis on dried blood spot cards: Experimental data using darolutamide and filgotinib.
Vinay Kiran, Abhishek Dixit, Bhavesh Babulal Gabani, Nuggehally R Srinivas, Ramesh Mullangi

Biomed Chromatogr· November 2020

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Simultaneous determination of colchicine and febuxostat in rat plasma: Application in a rat pharmacokinetic study.
Bhavesh Babulal Gabani, Neeraj Kumar Saini, Ravi Kumar Jairam, Pavan Shrinivas, Ravi Kumar Trivedi, Ramesh Mullangi

Biomed Chromatogr· November 2020

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Enantioselective LC-ESI-MS/MS method for quantitation of (-)-lumefantrine and (+)-lumefantrine in mice plasma and application to a pharmacokinetic study.
Vinay Kiran, Narayanan Balaji, Bhavesh Babulal Gabani, Manjuanth Bajantri, Rajesh Chandran, Ramesh Mullangi

Biomed Chromatogr· September 2020

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Validated LC-MS/MS Method for Simultaneous Quantitation of SAFit-1 and SAFit-2 in Mice Plasma: Application to a Pharmacokinetic Study.
Bhavesh Babulal Gabani, Suresh Ponnayyan Sulochana, Anup H A Siddesh, Vinay Kiran, Neeraj Kumar Saini, Ramesh Mullangi

Drug Res (Stuttg)· July 2020

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Discovery and optimization of novel phenyldiazepine and pyridodiazepine based Aurora kinase inhibitors.
Natarajan Tamizharasan, Chandru Gajendran, Rajendra Kristam, Suresh P Sulochana, Dhanalakshmi Sivanandhan, Ramesh Mullangi

Bioorg Chem· June 2020

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Development and Validation of an HPLC Method for Quantification of Filgotinib, a Novel JAK-1 Inhibitor in Mice Plasma: Application to a Pharmacokinetic Study.
Ashok Zakkula, Shobha Pulipati, Sreekanth Dittakavi, Ram Murthi Bestha, Mohd Zainuddin, Ramesh Mullangi

Drug Res (Stuttg)· May 2020

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Validated DBS method for filgotinib quantitation in rat dried blood spots and its application to a pharmacokinetic study in rats.
Abhishek Dixit, Vinay Kiran, Bhavesh Babulal Gabani, Ramesh Mullangi

ADMET DMPK· May 2020

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Validated LC-MS/MS method for quantitation of a selective JAK1 inhibitor, filgotinib in rat plasma, and its application to a pharmacokinetic study in rats.
Abhishek Dixit, Vinay Kiran, Bhavesh Babulal Gabani, Zainuddin Mohd, Ravi Kumar Trivedi, Ramesh Mullangi

Biomed Chromatogr· April 2020

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Preparation and optimization of nilotinib self-micro-emulsifying drug delivery systems to enhance oral bioavailability.
Ashok Zakkula, Bhavesh Babulal Gabani, Ravi Kumar Jairam, Vinay Kiran, Umesh Todmal, Ramesh Mullangi

Drug Dev Ind Pharm· March 2020

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Validated HPLC method for quantification of copanlisib in mice plasma: application to a pharmacokinetic study.
Ashok Zakkula, Pavan Kumar Kurakula, Sreekanth Dittakavi, Prasanthi Daram, Ram Murthi Bestha, Ramesh Mullangi

ADMET DMPK· March 2020

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