Publications by authors named "Munetake Shimabe"

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A Phase 1 Study of KHK4083: A Single-Blind, Randomized, Placebo-Controlled Single-Ascending-Dose Study in Healthy Adults and an Open-Label Multiple-Dose Study in Patients With Ulcerative Colitis.
Kenichi Furihata, Yoh Ishiguro, Naoki Yoshimura, Hiroaki Ito, Shinji Katsushima, Munetake Shimabe

Clin Pharmacol Drug Dev· August 2021

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Safety, tolerability and efficacy of repeated intravenous infusions of KHK4083, a fully human anti-OX40 monoclonal antibody, in Japanese patients with moderate to severe atopic dermatitis.
Hidemi Nakagawa, Hajime Iizuka, Osamu Nemoto, Munetake Shimabe, Yasunobu Furukawa

J Dermatol Sci· August 2020

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The novel CA IX inhibition antibody chKM4927 shows anti-tumor efficacy in vivo.
Ayami Yamaguchi, Katsuaki Usami, Munetake Shimabe, Kazumasa Hasegawa, Masao Asada

Anticancer Res· April 2015

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AML1/RUNX1 functions as a cytoplasmic attenuator of NF-κB signaling in the repression of myeloid tumors.
Masahiro Nakagawa, Munetake Shimabe, Naoko Watanabe-Okochi, Shunya Arai, Akihide Yoshimi

Blood· December 2011

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Evi1 is essential for hematopoietic stem cell self-renewal, and its expression marks hematopoietic cells with long-term multilineage repopulating activity.
Keisuke Kataoka, Tomohiko Sato, Akihide Yoshimi, Susumu Goyama, Takako Tsuruta, Munetake Shimabe

J Exp Med· November 2011

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Evi-1 is a transcriptional target of mixed-lineage leukemia oncoproteins in hematopoietic stem cells.
Shunya Arai, Akihide Yoshimi, Munetake Shimabe, Motoshi Ichikawa, Masahiro Nakagawa

Blood· June 2011

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Evi1 represses PTEN expression and activates PI3K/AKT/mTOR via interactions with polycomb proteins.
Akihide Yoshimi, Susumu Goyama, Naoko Watanabe-Okochi, Yumiko Yoshiki, Yasuhito Nannya, Munetake Shimabe

Blood· March 2011

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Evi-1 is a critical regulator for hematopoietic stem cells and transformed leukemic cells.
Susumu Goyama, Go Yamamoto, Munetake Shimabe, Tomohiko Sato, Motoshi Ichikawa

Cell Stem Cell· August 2008

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Switching constant domains enhances agonist activities of antibodies to a thrombopoietin receptor.
Masayuki Kai, Kazuhiro Motoki, Hideaki Yoshida, Chie Emuta, Yukiko Chisaka, Munetake Shimabe

Nat Biotechnol· February 2008

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Abnormal structural luteolysis in ovaries of the senescence accelerated mouse (SAM): expression of Fas ligand/Fas-mediated apoptosis signaling molecules in luteal cells.
Minako Kiso, Noboru Manabe, Kohji Komatsu, Munetake Shimabe, Hajime Miyamoto

J Reprod Dev· December 2003

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Soluble Fas (FasB) regulates luteal cell apoptosis during luteolysis in murine ovaries.
Kohji Komatsu, Noboru Manabe, Minako Kiso, Munetake Shimabe, Hajime Miyamoto

Mol Reprod Dev· August 2003

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Changes in localization of immune cells and cytokines in corpora lutea during luteolysis in murine ovaries.
Kohji Komatsu, Noboru Manabe, Minako Kiso, Munetake Shimabe, Hajime Miyamoto

J Exp Zool A Comp Exp Biol· April 2003

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