Publications by authors named "Murray D Norris"

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Network Modeling of microRNA-mRNA Interactions in Neuroblastoma Tumorigenesis Identifies miR-204 as a Direct Inhibitor of MYCN.
Chi Yan Ooi, Daniel R Carter, Bing Liu, Chelsea Mayoh, Anneleen Beckers, Amit Lalwani, Zsuzsanna Nagy, Sara De Brouwer, Bieke Decaesteker, Tzong-Tyng Hung

Cancer Res· June 2018

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Arginine depletion potentiates standard-of-care chemo-immunotherapy in preclinical models of high-risk neuroblastoma.
Kimberley M Hanssen, Jayne Murray, Ruby Pandher, Stephanie Alfred, Laura D Gamble, Murray D Norris

J Exp Clin Cancer Res· August 2025

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Polyamine depletion limits progression of acute leukaemia.
Weiman Gao, Mawar Karsa, Lin Xiao, Dayna Spurling, Ayu Karsa, Murray D Norris

Int J Cancer· June 2025

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The cell-permeable iron chelator M606 inhibits MYCN-driven neuroblastoma via an E2F3-mediated response.
Ruby Pandher, Chengyuan Xue, Laura D Gamble, Giorgio Milazzo, Simone Di Giacomo, Murray D Norris

Proc Natl Acad Sci U S A· June 2025

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The polyamine transporter ATP13A3 mediates difluoromethylornithine-induced polyamine uptake in neuroblastoma.
Mujahid Azfar, Weiman Gao, Chris Van den Haute, Lin Xiao, Mawar Karsa, Murray D Norris

Mol Oncol· March 2025

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Spatial profiling of endoplasmic reticulum stress markers in tumor associated cells predicts patient outcomes in pancreatic cancer.
Georgia Porter, Murray D Norris, Minoti Apte, Angelica M Merlot

Neoplasia· February 2025

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Combined inhibition of histone methyltransferases EZH2 and DOT1L is an effective therapy for neuroblastoma.
Janith A Seneviratne, Daenikka Ravindrarajah, Daniel R Carter, Vicki Zhai, Amit Lalwani, Murray D Norris

Cancer Med· November 2024

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Golgi-localized Ring Finger Protein 121 is necessary for MYCN-driven neuroblastoma tumorigenesis.
Belamy B Cheung, Ritu Mittra, Jayne Murray, Qian Wang, Janith A Seneviratne, Murray D Norris

Commun Biol· October 2024

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The transcriptional co-repressor Runx1t1 is essential for MYCN-driven neuroblastoma tumorigenesis.
Jayne E Murray, Emanuele Valli, Giorgio Milazzo, Chelsea Mayoh, Andrew J Gifford, Murray D Norris

Nat Commun· July 2024

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FDA-approved disulfiram as a novel treatment for aggressive leukemia.
Mawar Karsa, Lin Xiao, Emma Ronca, Angelika Bongers, Dayna Spurling, Murray D Norris

J Mol Med (Berl)· April 2024

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Phase 1 study of high-dose DFMO, celecoxib, cyclophosphamide and topotecan for patients with relapsed neuroblastoma: a New Approaches to Neuroblastoma Therapy trial.
Michael D Hogarty, David S Ziegler, Andrea Franson, Yueh-Yun Chi, Denice Tsao-Wei, Murray D Norris

Br J Cancer· March 2024

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Mitotic Dysregulation at Tumor Initiation Creates a Therapeutic Vulnerability to Combination Anti-Mitotic and Pro-Apoptotic Agents for MYCN-Driven Neuroblastoma.
Lei Zhai, Anushree Balachandran, Rebecca Larkin, Janith A Seneviratne, Sylvia A Chung, Murray D Norris

Int J Mol Sci· October 2023

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Delivery of PEGylated liposomal doxorubicin by bispecific antibodies improves treatment in models of high-risk childhood leukemia.
Ernest Moles, Christopher B Howard, Pie Huda, Mawar Karsa, Hannah McCalmont, Murray D Norris

Sci Transl Med· May 2023

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Inhibition of mitochondrial translocase SLC25A5 and histone deacetylation is an effective combination therapy in neuroblastoma.
Janith A Seneviratne, Daniel R Carter, Rituparna Mittra, Andrew Gifford, Patrick Y Kim, Murray D Norris

Int J Cancer· April 2023

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Memory of stochastic single-cell apoptotic signaling promotes chemoresistance in neuroblastoma.
Jordan F Hastings, Sharissa L Latham, Alvin Kamili, Madeleine S Wheatley, Jeremy Z R Han, Murray D Norris

Sci Adv· March 2023

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Inflammatory response to retrotransposons drives tumor drug resistance that can be prevented by reverse transcriptase inhibitors.
Ksenia A Novototskaya-Vlasova, Nickolay S Neznanov, Ivan Molodtsov, Brandon M Hall, Mairead Commane, Murray D Norris

Proc Natl Acad Sci U S A· December 2022

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Measurable residual disease analysis in paediatric acute lymphoblastic leukaemia patients with ABL-class fusions.
Nicola C Venn, Libby Huang, Lenka Hovorková, Walter Muskovic, Marie Wong, Murray D Norris

Br J Cancer· September 2022

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GSH facilitates the binding and inhibitory activity of novel multidrug resistance protein 1 (MRP1) modulators.
Kimberley M Hanssen, Madeleine S Wheatley, Denise M T Yu, Gwenaëlle Conseil, Murray D Norris

FEBS J· July 2022

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The Combination of Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Delays KMT2A-Rearranged Leukemia Progression.
Lin Xiao, Mawar Karsa, Emma Ronca, Angelika Bongers, Angelika Kosciolek, Murray D Norris

Front Oncol· May 2022

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In vitro and in vivo drug screens of tumor cells identify novel therapies for high-risk child cancer.
Loretta M S Lau, Chelsea Mayoh, Jinhan Xie, Paulette Barahona, Karen L MacKenzie, Murray D Norris

EMBO Mol Med· April 2022

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Suppression of the ABCA1 Cholesterol Transporter Impairs the Growth and Migration of Epithelial Ovarian Cancer.
Jixuan Gao, MoonSun Jung, Rebekka T Williams, Danica Hui, Amanda J Russell, Murray D Norris

Cancers (Basel)· April 2022

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Whole-genome sequencing facilitates patient-specific quantitative PCR-based minimal residual disease monitoring in acute lymphoblastic leukaemia, neuroblastoma and Ewing sarcoma.
Vinod Vijay Subhash, Libby Huang, Alvin Kamili, Marie Wong, Dan Chen, Murray D Norris

Br J Cancer· February 2022

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Systematic Evaluation of a Library of Approved and Pharmacologically Active Compounds for the Identification of Novel Candidate Drugs for KMT2A-Rearranged Leukemia.
Mawar Karsa, Emma Ronca, Angelika Bongers, Anna Mariana, Ernest Moles, Murray D Norris

Front Oncol· January 2022

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A Primer for Assessing the Pathology in Mouse Models of Neuroblastoma.
Andrew J Gifford, Jayne Murray, Jamie I Fletcher, Glenn M Marshall, Murray D Norris

Curr Protoc· November 2021

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Cell-Based Methods for the Identification of Myc-Inhibitory Small Molecules.
Catherine A Burkhart, Michelle Haber, Murray D Norris, Andrei V Gudkov, Mikhail A Nikiforov

Methods Mol Biol· August 2021

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Immunometabolism: A 'Hot' Switch for 'Cold' Pediatric Solid Tumors.
Lin Xiao, Harrison Yeung, Michelle Haber, Murray D Norris, Klaartje Somers

Trends Cancer· August 2021

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