Publications by authors named "Mustafa Ark"

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Development and optimization of Soluplus®/Pluronic-based polymeric micelles for bicalutamide delivery: characterization, lyophilization, stability, and cellular studies.
Nihal Tugce Ozaksun, Tugce Tayyar, Aysun Ozdemir, Mustafa Ark, Tuba Incecayir

Eur J Pharm Sci· December 2025

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Caveolae and Rho Kinase: their implication of the senescent cell morphology and the secretion of the SASP in HeLa and A549 cancer cells.
Yaprak Dilber Şimay Demir, Islam Mohammed Ahmed, Aysun Özdemir, Mustafa Ark

Med Oncol· September 2025

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Evaluating the Effect of SASP Factors on the Proliferation of Cancer Cells using A Comparative Analysis of Three Distinct Methodologies.
Yaprak Dilber Şimay Demir, Tuğçe Tayyar, Aysun Özdemir, Mustafa Ark

J Vis Exp· September 2025

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Temporal regulation of gene expression and pathways in chemotherapy-induced senescence in HeLa cervical cancer cell line.
Ceren Sucularli, Yaprak Dilber Şimay Demir, Aysun Özdemir, Mustafa Ark

Biosystems· March 2024

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Editorial: Cellular senescence in physiology and pathophysiology.
Mustafa Ark, Mohammad Nasir Uddin

Front Physiol· March 2023

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Senescent cells and SASP in cancer microenvironment: New approaches in cancer therapy.
Aysun Özdemir, Yaprak Dilber Şimay Demir, Zeynep Elif Yeşilyurt, Mustafa Ark

Adv Protein Chem Struct Biol· January 2023

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Effect of Finishing-Polishing Procedures on Cytotoxicity of Resin-Based Restorative Materials via Real-Time Cell Analysis.
Ceren Çimen, Fatma Funda Demirsoy, Aysun Özdemir, Mustafa Ark, Nurhan Özalp

J Clin Pediatr Dent· January 2022

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The implication of ROCK 2 as a potential senotherapeutic target via the suppression of the harmful effects of the SASP: Do senescent cancer cells really engulf the other cells?
Yaprak Dilber Şimay Demir, Aysun Özdemir, Ceren Sucularlı, Elifnur Benhür, Mustafa Ark

Cell Signal· August 2021

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A novel proteolytic cleavage of ROCK 1 in cell death: Not only by caspases 3 and 7 but also by caspase 2.
Aysun Özdemir, Burçin İbişoğlu, Yaprak Dilber Şimay Demir, Elifnur Benhür, Farzaneh Valipour, Mustafa Ark

Biochem Biophys Res Commun· April 2021

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Antimigratory effect of pyrazole derivatives through the induction of STAT1 phosphorylation in A549 cancer cells.
Yaprak Dilber Şimay Demir, Aysun Özdemir, Reyhan Gönbe Özdemir, Setenay Cemre Cevher, Burcu Çalışkan, Mustafa Ark

J Pharm Pharmacol· April 2021

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A novel ROCK inhibitor: off-target effects of metformin.
Aysun Özdemİr, Mustafa Ark

Turk J Biol· February 2021

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The connection between the cardiac glycoside-induced senescent cell morphology and Rho/Rho kinase pathway.
Yaprak Dilber Şimay, Aysun Özdemir, Burçin İbişoğlu, Mustafa Ark

Cytoskeleton (Hoboken)· November 2018

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Gemcitabine hydrochloride-loaded liposomes and nanoparticles: comparison of encapsulation efficiency, drug release, particle size, and cytotoxicity.
Tahir Emre Yalcin, Sibel Ilbasmis-Tamer, Burçin Ibisoglu, Aysun Özdemir, Mustafa Ark

Pharm Dev Technol· January 2018

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Promising anticancer activity of Cyclotrichium niveum L. extracts through induction of both apoptosis and necrosis.
Aysun Özdemir, Metin Yildiz, Fatma Sezer Senol, Yaprak Dilber Şimay, Burçin Ibişoglu, Mustafa Ark

Food Chem Toxicol· November 2017

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Cardiac glycoside-induced cell death and Rho/Rho kinase pathway: Implication of different regulation in cancer cell lines.
Aysun Özdemir, Yaprak Dilber Şimay, Burçin İbişoğlu, Biljana Yaren, Döne Bülbül, Mustafa Ark

Steroids· May 2016

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Atorvastatin acutely reduces the reactivity to spasmogens in rat aorta: implication of the inhibition of geranylgeranylation and MYPT-1 phosphorylation.
Fatoş İlkay Alp Yildirim, Deniz Kaleli Durman, Eda Aypar, Mustafa Ark, Osman Özdemir

Fundam Clin Pharmacol· April 2016

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Chronic ouabain treatment induces Rho kinase activation.
Aysun Ozdemir, Gürkan Şahan, Ayşegül Demirtaş, Eda Aypar, Gürkan Gözübüyük, Mustafa Ark

Arch Pharm Res· October 2015

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The effect of taurine on the relationship between NO, ADMA and homocysteine in endotoxin-mediated inflammation in HUVEC cultures.
Ozge Tugce Pasaoglu, Nurten Turkozkan, Mustafa Ark, Belgin Polat, Mehmet Agilli

Inflammation· October 2014

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Synthesis and pharmacological evaluation of some novel thebaine derivatives: N-(tetrazol-1H-5-yl)-6,14-endoethenotetrahydrothebaine incorporating the 1,3,4-oxadiazole or the 1,3,4-thiadiazole moiety.
Serkan Yavuz, Yusuf Ünal, Özgür Pamir, Demet Yılmazer, Ömer Kurtipek, Mustafa Ark

Arch Pharm (Weinheim)· June 2013

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Involvement of Rho kinase (ROCK) in sepsis-induced acute lung injury.
Ismail Cinel, Mustafa Ark, Phillip Dellinger, Tuba Karabacak, Lulufer Tamer

J Thorac Dis· February 2012

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Ouabain-induced apoptosis and Rho kinase: a novel caspase-2 cleavage site and fragment of Rock-2.
Mustafa Ark, Aysun Ozdemir, Belgin Polat

Apoptosis· December 2010

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Chemical preconditioning effect of 3-nitropropionic acid in anesthetized rat heart.
Nilufer Nermin Turan, Bilgen Basgut, Eda Aypar, Mustafa Ark, Alper B Iskit

Life Sci· April 2008

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Nitric oxide does not downregulate Rho-kinase (ROCK-2) expression in rat coronary endothelial cells.
R Nalan Tiftik, Ayşe Erol, Mehtap G Cnar, Havva Kubat, Mustafa Ark

J Cardiovasc Pharmacol· February 2008

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Involvement of rho kinase in the ouabain-induced contractions of the rat renal arteries.
Mustafa Ark, Havva Kubat, Hüseyin Beydaği, Tolgay Ergenoğlu, Emel Songu-Mize

Biochem Biophys Res Commun· February 2006

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Comparison of spectrophotometric, HPLC and chemiluminescence methods for 3-nitrotyrosine and peroxynitrite interaction.
Nilufer Nermin Turan, Mustafa Ark, Abdullah Tuncay Demiryurek

Arch Pharm Res· March 2005

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