Publications by authors named "Nadia Coltella"

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Tumor-targeted cytokine delivery by engineered myeloid cells unlocks CAR T cell efficacy and endogenous T cell responses in glioblastoma.
Federico Rossari, Giorgia Alvisi, Nadia Coltella, Luigi Naldini

Mol Ther· August 2025

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A cross-talk established by tumor-targeted cytokines rescues CAR T cell activity and engages host T cells against glioblastoma in mice.
Federico Rossari, Giorgia Alvisi, Melania Cusimano, Stefano Beretta, Filippo Birocchi, Nadia Coltella

Sci Transl Med· July 2025

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The transcription factor HIF2α partakes in the differentiation block of acute myeloid leukemia.
Daniela Magliulo, Matilde Simoni, Carolina Caserta, Cristina Fracassi, Serena Belluschi, Nadia Coltella

EMBO Mol Med· November 2023

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In vivo macrophage engineering reshapes the tumor microenvironment leading to eradication of liver metastases.
Thomas Kerzel, Giovanna Giacca, Stefano Beretta, Chiara Bresesti, Marco Notaro, Nadia Coltella

Cancer Cell· November 2023

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Gene-based delivery of immune-activating cytokines for cancer treatment.
Federico Rossari, Filippo Birocchi, Luigi Naldini, Nadia Coltella

Trends Mol Med· April 2023

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Targeted inducible delivery of immunoactivating cytokines reprograms glioblastoma microenvironment and inhibits growth in mouse models.
Filippo Birocchi, Melania Cusimano, Federico Rossari, Stefano Beretta, Paola M V Rancoita, Nadia Coltella

Sci Transl Med· July 2022

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A Set of Cell Lines Derived from a Genetic Murine Glioblastoma Model Recapitulates Molecular and Morphological Characteristics of Human Tumors.
Barbara Costa, Michael N C Fletcher, Pavle Boskovic, Ekaterina L Ivanova, Tanja Eisemann, Nadia Coltella

Cancers (Basel)· January 2021

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EZN-2208 treatment suppresses chronic lymphocytic leukaemia by interfering with environmental protection and increases response to fludarabine.
Roberta Valsecchi, Nadia Coltella, Daniela Magliulo, Lucia Bongiovanni, Lydia Scarfò

Open Biol· May 2020

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PML promotes metastasis of triple-negative breast cancer through transcriptional regulation of HIF1A target genes.
Manfredi Ponente, Letizia Campanini, Roberto Cuttano, Andrea Piunti, Giacomo A Delledonne, Nadia Coltella

JCI Insight· February 2017

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24-Hydroxycholesterol participates in pancreatic neuroendocrine tumor development.
Matias Soncini, Gianfranca Corna, Marta Moresco, Nadia Coltella, Umberto Restuccia

Proc Natl Acad Sci U S A· October 2016

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Hypoxia inducible factor-1α regulates a pro-invasive phenotype in acute monocytic leukemia.
Jessica Migliavacca, Stefano Percio, Roberta Valsecchi, Elisabetta Ferrero, Antonello Spinelli, Nadia Coltella

Oncotarget· August 2016

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HIF-1α regulates the interaction of chronic lymphocytic leukemia cells with the tumor microenvironment.
Roberta Valsecchi, Nadia Coltella, Daniela Belloni, Manfredi Ponente, Elisa Ten Hacken

Blood· April 2016

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Synergistic Leukemia Eradication by Combined Treatment with Retinoic Acid and HIF Inhibition by EZN-2208 (PEG-SN38) in Preclinical Models of PML-RARα and PLZF-RARα-Driven Leukemia.
Nadia Coltella, Roberta Valsecchi, Manfredi Ponente, Maurilio Ponzoni, Rosa Bernardi

Clin Cancer Res· August 2015

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A HIF-1 network reveals characteristics of epithelial-mesenchymal transition in acute promyelocytic leukemia.
Stefano Percio, Nadia Coltella, Sara Grisanti, Rosa Bernardi, Linda Pattini

Genome Med· December 2014

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Bone marrow endosteal mesenchymal progenitors depend on HIF factors for maintenance and regulation of hematopoiesis.
Jlenia Guarnerio, Nadia Coltella, Ugo Ala, Giovanni Tonon, Pier Paolo Pandolfi

Stem Cell Reports· June 2014

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HIF factors cooperate with PML-RARα to promote acute promyelocytic leukemia progression and relapse.
Nadia Coltella, Stefano Percio, Roberta Valsecchi, Roberto Cuttano, Jlenia Guarnerio

EMBO Mol Med· May 2014

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Pml represses tumour progression through inhibition of mTOR.
Rosa Bernardi, Antonella Papa, Ainara Egia, Nadia Coltella, Julie Teruya-Feldstein

EMBO Mol Med· May 2011

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Fumarase tumor suppressor gene and MET oncogene cooperate in upholding transformation and tumorigenesis.
Barbara Costa, Daniela Dettori, Annalisa Lorenzato, Chiara Bardella, Nadia Coltella

FASEB J· August 2010

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The therapeutic potential of hepatocyte growth factor to sensitize ovarian cancer cells to cisplatin and paclitaxel in vivo.
Chiara Bardella, Daniela Dettori, Martina Olivero, Nadia Coltella, Massimiliano Mazzone

Clin Cancer Res· April 2007

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Hepatocyte growth factor installs a survival platform for colorectal cancer cell invasive growth and overcomes p38 MAPK-mediated apoptosis.
Michela Fassetta, Lorenza D'Alessandro, Nadia Coltella, Maria Flavia Di Renzo, Andrea Rasola

Cell Signal· November 2006

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p38 MAPK downregulates phosphorylation of Bad in doxorubicin-induced endothelial apoptosis.
Simone Grethe, Nadia Coltella, Maria Flavia Di Renzo, M Isabella Pörn-Ares

Biochem Biophys Res Commun· September 2006

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p38 MAPK turns hepatocyte growth factor to a death signal that commits ovarian cancer cells to chemotherapy-induced apoptosis.
Nadia Coltella, Andrea Rasola, Elisa Nano, Chiara Bardella, Michela Fassetta

Int J Cancer· June 2006

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MET overexpression turns human primary osteoblasts into osteosarcomas.
Salvatore Patanè, Sofia Avnet, Nadia Coltella, Barbara Costa, Simone Sponza

Cancer Res· May 2006

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Genes regulated by hepatocyte growth factor as targets to sensitize ovarian cancer cells to cisplatin.
Martina Olivero, Tina Ruggiero, Silvia Saviozzi, Andrea Rasola, Nadia Coltella

Mol Cancer Ther· May 2006

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Role of the MET/HGF receptor in proliferation and invasive behavior of osteosarcoma.
Nadia Coltella, Maria Cristina Manara, Vanessa Cerisano, Livio Trusolino, Maria Flavia Di Renzo

FASEB J· June 2003

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