Publications by authors named "Naima Hanoun"

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Detection of EGFR mutations at pM concentration in ten minutes using a microfluidic concentration and separation module.
Jeffrey Teillet, Anne Pradines, Naima Hanoun, Jules Edwards, Pierre Joseph

Biomed Microdevices· August 2025

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Sizing and concentration analysis of cfDNA using Biabooster technology: Results from a prospective plasma-based collection of 77 patients with locally advanced unresectable esophageal cancer.
Anouchka Modesto, Sophie Gibert, Caroline Delmas, David Tougeron, Amaury Paumier, Naïma Hanoun

Int J Cancer· June 2025

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Prognostic impact of circulating tumor DNA detection in portal and peripheral blood in resected pancreatic ductal adenocarcinoma patients.
Charlotte Maulat, Cindy Canivet, Bastien Cabarrou, Anne Pradines, Janick Selves, Naïma Hanoun

Sci Rep· November 2024

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The E3 ubiquitin ligase TRIP12 is required for pancreatic acinar cell plasticity and pancreatic carcinogenesis.
Manon Brunet, Claire Vargas, Marjorie Fanjul, Damien Varry, Naïma Hanoun

J Pathol· August 2024

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Cytidine deaminase-dependent mitochondrial biogenesis as a potential vulnerability in pancreatic cancer cells.
Audrey Frances, Audrey Lumeau, Nicolas Bery, Marion Gayral, Lucille Stuani, Naïma Hanoun

Commun Biol· August 2024

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Cytidine Deaminase Resolves Replicative Stress and Protects Pancreatic Cancer from DNA-Targeting Drugs.
Audrey Lumeau, Nicolas Bery, Audrey Francès, Marion Gayral, Guillaume Labrousse, Naima Hanoun

Cancer Res· April 2024

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Preclinical development of non-viral gene therapy for patients with advanced pancreatic cancer.
Odile Barbey, Hubert Lulka, Naima Hanoun, Hafid Belhadj-Tahar, Fabienne Vernejoul

Mol Ther Methods Clin Dev· June 2023

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The antitumoral activity of TLR7 ligands is corrupted by the microenvironment of pancreatic tumors.
Marie Rouanet, Naima Hanoun, Hubert Lulka, Cindy Ferreira, Pierre Garcin

Mol Ther· April 2022

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Initial Characterization of Integrase-Defective Lentiviral Vectors for Pancreatic Cancer Gene Therapy.
Naima Hanoun, Marion Gayral, Adeline Pointreau, Louis Buscail, Pierre Cordelier

Hum Gene Ther· February 2016

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First-in-man phase 1 clinical trial of gene therapy for advanced pancreatic cancer: safety, biodistribution, and preliminary clinical findings.
Louis Buscail, Barbara Bournet, Fabienne Vernejoul, Gilles Cambois, Hubert Lulka, Naïma Hanoun

Mol Ther· April 2015

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Targeted oncolytic herpes simplex virus type 1 eradicates experimental pancreatic tumors.
Marion Gayral, Hubert Lulka, Naima Hanoun, Coline Biollay, Janick Sèlves

Hum Gene Ther· February 2015

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Endoscopic ultrasound-guided fine-needle aspiration biopsy coupled with a KRAS mutation assay using allelic discrimination improves the diagnosis of pancreatic cancer.
Barbara Bournet, Janick Selves, David Grand, Marie Danjoux, Naima Hanoun

J Clin Gastroenterol· January 2015

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The E3 ubiquitin ligase thyroid hormone receptor-interacting protein 12 targets pancreas transcription factor 1a for proteasomal degradation.
Naïma Hanoun, Samuel Fritsch, Odile Gayet, Véronique Gigoux, Pierre Cordelier

J Biol Chem· December 2014

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MicroRNAs as emerging biomarkers and therapeutic targets for pancreatic cancer.
Marion Gayral, Sébastien Jo, Naima Hanoun, Alix Vignolle-Vidoni, Hubert Lulka

World J Gastroenterol· August 2014

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The Role of the 3' Untranslated Region in the Post-Transcriptional Regulation of KLF6 Gene Expression in Hepatocellular Carcinoma.
Thoria Diab, Naima Hanoun, Christophe Bureau, Camille Christol, Louis Buscail

Cancers (Basel)· December 2013

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The rescue of miR-148a expression in pancreatic cancer: an inappropriate therapeutic tool.
Yannick Delpu, Hubert Lulka, Flavie Sicard, Nathalie Saint-Laurent, Frédéric Lopez, Naïma Hanoun

PLoS One· July 2013

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Oxidative stress induced by inactivation of TP53INP1 cooperates with KrasG12D to initiate and promote pancreatic carcinogenesis in the murine pancreas.
Talal Al Saati, Pascal Clerc, Naïma Hanoun, Sylvain Peuget, Hubert Lulka

Am J Pathol· June 2013

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Role of endothelial AADC in cardiac synthesis of serotonin and nitrates accumulation.
Charlotte Rouzaud-Laborde, Naïma Hanoun, Ipek Baysal, Jean-Simon Rech, Céline Mias

PLoS One· December 2012

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Genetic and epigenetic alterations in pancreatic carcinogenesis.
Yannick Delpu, Naïma Hanoun, Hubert Lulka, Flavie Sicard, Janick Selves

Curr Genomics· March 2011

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The SV2 variant of KLF6 is down-regulated in hepatocellular carcinoma and displays anti-proliferative and pro-apoptotic functions.
Naïma Hanoun, Christophe Bureau, Thoria Diab, Odile Gayet, Nelson Dusetti

J Hepatol· November 2010

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The silencing of microRNA 148a production by DNA hypermethylation is an early event in pancreatic carcinogenesis.
Naïma Hanoun, Yannick Delpu, Arief A Suriawinata, Barbara Bournet, Christophe Bureau

Clin Chem· July 2010

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Parkin deficiency delays motor decline and disease manifestation in a mouse model of synucleinopathy.
Margot Fournier, Jérémie Vitte, Jérôme Garrigue, Dominique Langui, Jean-Philippe Dullin, Naïma Hanoun

PLoS One· August 2009

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Expression and Function of Kruppel Like-Factors (KLF) in Carcinogenesis.
Christophe Bureau, Naima Hanoun, Jérôme Torrisani, Jean-Pierre Vinel, Louis Buscail

Curr Genomics· August 2009

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Differential long-term effects of MDMA on the serotoninergic system and hippocampal cell proliferation in 5-HTT knock-out vs. wild-type mice.
Thibault Renoir, Eleni Païzanis, Malika El Yacoubi, Françoise Saurini, Naïma Hanoun

Int J Neuropsychopharmacol· December 2008

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Chronic voluntary ethanol intake hypersensitizes 5-HT(1A) autoreceptors in C57BL/6J mice.
Sabah Kelaï, Thibault Renoir, Laurent Chouchana, Françoise Saurini, Naïma Hanoun

J Neurochem· December 2008

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