Publications by authors named "Nan Fu Chen"

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Artificial Intelligence-Based In Silico Evaluation of the Pharmacological Potential and In Vitro Anti-Malignancy Effect in the Human Glioblastoma Cell Line of the Hydrate of the Coumarin Compound Meranzin Originating From the Edible Macroalga ().
Shi-Ying Huang, Yi-Chen Chang, Charles Chien-Chih Chiu, Chang-Wei Hsieh, Chien-Wei Feng, Zhi-Cheng Chen, Nan-Fu Chen, Cheng-Chieh Fang

Food Sci Nutr· January 2026

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Potential anti-ovarian cancer agent: Isoaaptamine interference epithelial-mesenchymal transition, induces intrinsic apoptosis, and suppresses angiogenesis.
I-Li Su, Yen-Po Chen, Ling-Chen Hsu, Chien-Wei Feng, Kuan-Hao Tsui, Nan-Fu Chen

Eur J Pharmacol· October 2025

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Intrathecal STAT3 inhibitor Bt354 ameliorates chronic constriction injury-induced nociceptive sensitization by modulating neuroinflammation.
Hao-Jung Cheng, Nan-Fu Chen, Yueh-Chiao Tang, Po-Chang Shih, Wu-Fu Chen

Neurotherapeutics· October 2025

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Antinociceptive and anti-inflammatory effects of dihydroaustrasulfone alcohol in alleviating peripheral neuropathy via Nrf2/HO-1 pathway in rats.
Chun-Sung Sung, Hao-Jung Cheng, San-Nan Yang, Pei-Jyuan Li, Shi-Ying Huang, Wu-Fu Chen, Nan-Fu Chen

Neurochem Int· September 2025

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The Neuroprotective Effects of the Crinoid Natural Compound Rhodoptilometrin in Parkinson's Disease Experimental Models: Implications for ER Stress and Autophagy Modulation.
Zhi-Hong Wen, Ya-Jen Chiu, San-Nan Yang, Bo-Lin Guo, Chien-Wei Feng, Nan-Fu Chen, Wu-Fu Chen

ACS Chem Neurosci· July 2025

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Varying Analgesic Effectiveness of Systemic and Central Intrathecal Administration of Cyclooxygenase-2 Inhibitors in Different Phases of Osteoarthritic Pain in Rats.
Chun-Sung Sung, Shi-Ying Huang, Hao-Jung Cheng, Sung-Chun Lin, Zong-Sheng Wu, Nan-Fu Chen

Eur J Pain· July 2025

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Intrathecal Fumagillin Alleviates Chronic Neuropathy-Induced Nociceptive Sensitization and Modulates Spinal Astrocyte-Neuronal Glycolytic and Angiogenic Proteins.
Zhi-Hong Wen, Zong-Sheng Wu, Hao-Jung Cheng, Shi-Ying Huang, Shih-Hsuan Tang, Nan-Fu Chen

Mol Neurobiol· January 2025

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Upregulated spinal histone deacetylases induce nociceptive sensitization by inhibiting the GABA system in chronic constriction injury-induced neuropathy in rats.
Zhi-Hong Wen, Nan-Fu Chen, Hao-Jung Cheng, Hsiao-Mei Kuo, Pei-Yu Chen, Wu-Fu Chen

Pain Rep· December 2024

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Intrathecal lactate dehydrogenase A inhibitors FX11 and oxamate alleviate chronic constriction injury-induced nociceptive sensitization through neuroinflammation and angiogenesis.
Hao-Jung Cheng, Nan-Fu Chen, Wu-Fu Chen, Zong-Sheng Wu, Yu-Yo Sun

J Headache Pain· November 2024

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The anti-angiogenic and anti-vasculogenic mimicry effects of GN25 in endothelial and glioma cells.
Zhi-Hong Wen, Long Chang, San-Nan Yang, Chen-Ling Yu, Fang-Yu Tung, I-Chen Lu, Wu-Fu Chen, Nan-Fu Chen

Biochim Biophys Acta Mol Cell Res· October 2024

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Soft Corals-derived Dihydrosinularin Attenuates Neuronal Apoptosis in 6-hydroxydopamine-induced Cell Model of Parkinson's Disease by Regulating the PI3K Pathway.
Zhi-Hong Wen, Ya-Jen Chiu, San-Nan Yang, Tzu-Yi Huang, Chien-Wei Feng, Nan-Fu Chen, Wu-Fu Chen

Curr Med Chem· September 2024

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Gene expression profiling and the isocitrate dehydrogenase mutational landscape of temozolomide‑resistant glioblastoma.
Wu-Fu Chen, Jimmy Ming-Jung Chuang, San-Nan Yang, Nan-Fu Chen, Manojit Bhattacharya

Oncol Lett· August 2024

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STAT3 phosphorylation inhibitor Bt354 exhibits anti-neoplastic activity in glioblastoma multiforme cells.
Yi-Chun Chiang, Padhmavathi Selvam, You-Xuan Liu, Po-Chang Shih, Nan-Fu Chen, Wu-Fu Chen

Environ Toxicol· June 2024

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Frailty Prevention Care Management Program (FPCMP) on Frailty and Health Function in Community-Dwelling Older Adults: A Quasi-Experimental Trial Protocol.
Chia-Hui Lin, Ming-Yi Liu, Nan-Fu Chen

Healthcare (Basel)· December 2023

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Oral Administration of Protease-Soluble Chicken Type II Collagen Ameliorates Anterior Cruciate Ligament Transection-Induced Osteoarthritis in Rats.
Nan-Fu Chen, Yen-You Lin, Zhi-Kang Yao, Chung-Chih Tseng, Yu-Wei Liu

Nutrients· August 2023

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Manoalide Induces Intrinsic Apoptosis by Oxidative Stress and Mitochondrial Dysfunction in Human Osteosarcoma Cells.
Zhi-Kang Yao, Yen-Hsuan Jean, Sung-Chun Lin, Yu-Cheng Lai, Nan-Fu Chen, Wu-Fu Chen

Antioxidants (Basel)· July 2023

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Isoaaptamine increases ROS levels causing autophagy and mitochondria-mediated apoptosis in glioblastoma multiforme cells.
Zhi-Hong Wen, Hsiao-Mei Kuo, Po-Chang Shih, Ling-Chen Hsu, Jimmy Ming-Jung Chuang, Nan-Fu Chen, Wu-Fu Chen

Biomed Pharmacother· April 2023

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Antinociceptive Effects of Aaptamine, a Sponge Component, on Peripheral Neuropathy in Rats.
Chun-Sung Sung, Hao-Jung Cheng, Nan-Fu Chen, Shih-Hsuan Tang, Hsiao-Mei Kuo, Wu-Fu Chen

Mar Drugs· February 2023

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Sinularin Induces Oxidative Stress-Mediated Apoptosis and Mitochondrial Dysfunction, and Inhibits Angiogenesis in Glioblastoma Cells.
Shih-Yuan Hsu, Zhi-Hong Wen, Po-Chang Shih, Hsiao-Mei Kuo, Sung-Chun Lin, Wu-Fu Chen, Nan-Fu Chen

Antioxidants (Basel)· July 2022

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Investigation of the Characteristics and Antibacterial Activity of Polymer-Modified Copper Oxide Nanoparticles.
Nan-Fu Chen, Yu-Hsiang Liao, Pei-Ying Lin, Wu-Fu Chen, Zhi-Hong Wen, Shuchen Hsieh

Int J Mol Sci· November 2021

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Fumagillin Attenuates Spinal Angiogenesis, Neuroinflammation, and Pain in Neuropathic Rats after Chronic Constriction Injury.
Zhi-Hong Wen, Shi-Ying Huang, Hsiao-Mei Kuo, Chao-Ting Chen, Nan-Fu Chen, Wu-Fu Chen

Biomedicines· September 2021

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Glutathione S-Transferase M3 Is Associated with Glycolysis in Intrinsic Temozolomide-Resistant Glioblastoma Multiforme Cells.
Shu-Yu Cheng, Nan-Fu Chen, Zhi-Hong Wen, Zhi-Kang Yao, Kuan-Hao Tsui, Wu-Fu Chen

Int J Mol Sci· June 2021

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Effects of on anterior cruciate ligament transection-induced early osteoarthritis in rats.
Yen-You Lin, Nan-Fu Chen, San-Nan Yang, Yen-Hsuan Jean, Hsiao-Mei Kuo, Pei-Chin Chen, Yu-Cheng Lai

Exp Ther Med· March 2021

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Polydopamine Ultrathin Film Growth on Mica via In-Situ Polymerization of Dopamine with Applications for Silver-Based Antimicrobial Coatings.
Zheng-Hao Huang, Shi-Wei Peng, Shu-Ling Hsieh, Rajendranath Kirankumar, Po-Feng Huang, Nan-Fu Chen, Shuchen Hsieh

Materials (Basel)· February 2021

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Therapeutic Role of Protein Tyrosine Phosphatase 1B in Parkinson's Disease via Antineuroinflammation and Neuroprotection and .
Chien-Wei Feng, Nan-Fu Chen, Te-Fu Chan, Wu-Fu Chen

Parkinsons Dis· December 2020

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