Publications by authors named "Nanco Hefting"

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Safety and Tolerability of Brexpiprazole in Participants with Agitation Associated with Dementia due to Alzheimer's Disease: Pooled Analysis of Three Randomized Trials and an Extension Trial.
Alpesh Shah, Alvin Estilo, Pamela L Sheridan, Uwa Kalu, Dalei Chen, Nanco Hefting

CNS Drugs· October 2025

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Fixed-Dose Brexpiprazole and Sertraline Combination Therapy for the Treatment of Posttraumatic Stress Disorder: A Phase 3, Randomized Trial.
Lori L Davis, Saloni Behl, Daniel Lee, Hui Zeng, Taisa Skubiak, Nanco Hefting

J Clin Psychopharmacol· October 2025

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Safety and Tolerability of Brexpiprazole in Adolescents With Schizophrenia: A Long-Term, Open-Label Study.
Sarah D Atkinson, Alpesh Shah, Maria Victoria Burgess, Nanco Hefting, Dalei Chen

JAACAP Open· June 2025

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Safety and Efficacy of Brexpiprazole in the Treatment of Irritability Associated with Autism Spectrum Disorder: An 8-Week, Phase 3, Randomized, Double-Blind, Placebo-Controlled Trial and 26-Week Open-Label Extension in Children and Adolescents.
Caroline Ward, Ann Childress, Krista Martinko, Dalei Chen, Klaus Groes Larsen, Nanco Hefting

J Child Adolesc Psychopharmacol· May 2025

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Efficacy and safety of brexpiprazole in adolescents with schizophrenia: a multicountry, randomised, double-blind, placebo-controlled, phase 3 trial with an active reference.
Caroline Ward, Milica Pejović Milovančević, Eva Kohegyi, Nanco Hefting, Catherine Aurang

Lancet Psychiatry· May 2025

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Brexpiprazole and Sertraline Combination Treatment in Posttraumatic Stress Disorder: A Phase 3 Randomized Clinical Trial.
Lori L Davis, Saloni Behl, Daniel Lee, Hui Zeng, Taisa Skubiak, Nanco Hefting

JAMA Psychiatry· March 2025

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Brexpiprazole in Combination With Sertraline and as Monotherapy in Posttraumatic Stress Disorder: A Full-Factorial Randomized Clinical Trial.
Mary Hobart, Denise Chang, Nanco Hefting, Lori L Davis

J Clin Psychiatry· February 2025

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Brexpiprazole for the treatment of agitation associated with dementia due to Alzheimer's disease: A 12-week, active-treatment, extension trial.
Saloni Behl, Mary Slomkowski, Dalei Chen, Denise Chang, Nanco Hefting

J Alzheimers Dis· November 2024

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A randomised study and an extension study of brexpiprazole in patients with borderline personality disorder.
Brian Rothman, Claudette Brewer, Denise Chang, Mary Hobart, Nanco Hefting

Acta Neuropsychiatr· November 2024

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A double-blind, placebo-controlled, randomised withdrawal study of adjunctive brexpiprazole maintenance treatment for major depressive disorder.
Roger S McIntyre, Kripa Sundararajan, Saloni Behl, Nanco Hefting, Na Jin

Acta Neuropsychiatr· October 2024

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Defining a clinically meaningful within-patient change threshold for the Cohen-Mansfield Agitation Inventory in Alzheimer's dementia.
Juliette Meunier, Kristin Creel, Angély Loubert, Klaus Groes Larsen, Jyoti Aggarwal, Nanco Hefting

Front Neurol· July 2024

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Consistency checks to improve measurement with the Young Mania Rating Scale (YMRS).
Jonathan Rabinowitz, Robert C Young, Christian Yavorsky, Janet B W Williams, Jan Sedway, Nanco Hefting

J Affect Disord· January 2024

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Brexpiprazole for the Treatment of Agitation in Alzheimer Dementia: A Randomized Clinical Trial.
Daniel Lee, Mary Slomkowski, Nanco Hefting, Dalei Chen, Klaus Groes Larsen

JAMA Neurol· December 2023

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Defining Clinical Trial Estimands: A Practical Guide for Study Teams with Examples Based on a Psychiatric Disorder.
Elena Polverejan, Michael O'Kelly, Nanco Hefting, Jonathan D Norton, Pilar Lim

Ther Innov Regul Sci· September 2023

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Consistency checks to improve measurement with the Hamilton Rating Scale for Anxiety (HAM-A).
Jonathan Rabinowitz, Janet B W Williams, Nanco Hefting, Ariana Anderson, Brianne Brown

J Affect Disord· March 2023

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Consistency checks to improve measurement with the Hamilton Rating Scale for Depression (HAM-D).
Jonathan Rabinowitz, Janet B W Williams, Ariana Anderson, Dong Jing Fu, Nanco Hefting

J Affect Disord· April 2022

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Effects of Brexpiprazole on Functioning in Patients With Schizophrenia: Post Hoc Analysis of Short- and Long-Term Studies.
Christoph U Correll, Ying He, François Therrien, Erin MacKenzie, Stine R Meehan, Nanco Hefting

J Clin Psychiatry· March 2022

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Two randomized, double-blind, placebo-controlled trials and one open-label, long-term trial of brexpiprazole for the acute treatment of bipolar mania.
Eduard Vieta, Gary Sachs, Denise Chang, Johan Hellsten, Claudette Brewer, Nanco Hefting

J Psychopharmacol· August 2021

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Effects of Brexpiprazole Across Symptom Domains in Patients With Schizophrenia: Analysis of Short- and Long-Term Studies.
Stephen R Marder, Stine R Meehan, Catherine Weiss, Dalei Chen, Mary Hobart, Nanco Hefting

Schizophr Bull Open· January 2021

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A Long-Term, Open-Label Study to Evaluate the Safety and Tolerability of Brexpiprazole as Adjunctive Therapy in Adults With Major Depressive Disorder.
Mary Hobart, Peter Zhang, Aleksandar Skuban, Claudette Brewer, Nanco Hefting

J Clin Psychopharmacol· August 2019

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A randomised, placebo-controlled 24-week study evaluating adjunctive brexpiprazole in patients with major depressive disorder.
Michael Bauer, Nanco Hefting, Annika Lindsten, Mette Krog Josiassen, Mary Hobart

Acta Neuropsychiatr· February 2019

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Adjunctive brexpiprazole for elderly patients with major depressive disorder: An open-label, long-term safety and tolerability study.
Ulla Lepola, Nanco Hefting, Doris Zhang, Mary Hobart

Int J Geriatr Psychiatry· October 2018

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A Randomized, Placebo-Controlled Study of the Efficacy and Safety of Fixed-Dose Brexpiprazole 2 mg/d as Adjunctive Treatment of Adults With Major Depressive Disorder.
Mary Hobart, Aleksandar Skuban, Peter Zhang, Carole Augustine, Claudette Brewer, Nanco Hefting

J Clin Psychiatry· May 2018

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Efficacy and safety of flexibly dosed brexpiprazole for the adjunctive treatment of major depressive disorder: a randomized, active-referenced, placebo-controlled study.
Mary Hobart, Aleksandar Skuban, Peter Zhang, Mette Krog Josiassen, Nanco Hefting

Curr Med Res Opin· April 2018

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