Publications by authors named "Nancy A Jenkins"

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The common murine retroviral integration site activating Hhex marks a distal regulatory enhancer co-opted in human early T-cell precursor leukemia.
Joyce Hardwick, Javier Rodriguez-Hernaez, Giovanni Gambi, Bryan J Venters, Yan Guo, Nancy A Jenkins

J Biol Chem· March 2025

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Novel mechanisms of MITF regulation identified in a mouse suppressor screen.
Hong Nhung Vu, Matti Már Valdimarsson, Sara Sigurbjörnsdóttir, Kristín Bergsteinsdóttir, Julien Debbache, Nancy A Jenkins

EMBO Rep· October 2024

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Sleeping Beauty transposon mutagenesis in mouse intestinal organoids identifies genes involved in tumor progression and metastasis.
Naoko Iida, Yukari Muranaka, Jun Won Park, Shigeki Sekine, Neal G Copeland, Nancy A Jenkins

Cancer Gene Ther· April 2024

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Novel mechanisms of MITF regulation and melanoma predisposition identified in a mouse suppressor screen.
Hong Nhung Vu, Matti Már Valdimarsson, Sara Sigurbjörnsdóttir, Kristín Bergsteinsdóttir, Julien Debbache, Nancy A Jenkins

bioRxiv· August 2023

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TNF receptor-related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF-κB-inducing kinase-mediated hepatocyte transdifferentiation.
Yuto Shiode, Takahiro Kodama, Satoshi Shigeno, Kazuhiro Murai, Satoshi Tanaka, Nancy A Jenkins

Hepatology· February 2023

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Ring Finger Protein 125 Is an Anti-Proliferative Tumor Suppressor in Hepatocellular Carcinoma.
Takahiro Kodama, Michiko Kodama, Nancy A Jenkins, Neal G Copeland, Huanhuan Joyce Chen

Cancers (Basel)· May 2022

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Sleeping Beauty Transposon Mutagenesis Identifies Genes Driving the Initiation and Metastasis of Uterine Leiomyosarcoma.
Michiko Kodama, Hiroko Shimura, Jean C Tien, Justin Y Newberg, Takahiro Kodama, Nancy A Jenkins

Cancer Res· November 2021

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Transposon mutagenesis identifies cooperating genetic drivers during keratinocyte transformation and cutaneous squamous cell carcinoma progression.
Aziz Aiderus, Justin Y Newberg, Liliana Guzman-Rojas, Ana M Contreras-Sandoval, Amanda L Meshey, Nancy A Jenkins

PLoS Genet· August 2021

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Identification of cancer driver genes using Sleeping Beauty transposon mutagenesis.
Haruna Takeda, Nancy A Jenkins, Neal G Copeland

Cancer Sci· June 2021

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Ubiquitin specific peptidase 32 acts as an oncogene in epithelial ovarian cancer by deubiquitylating farnesyl-diphosphate farnesyltransferase 1.
Aya Nakae, Michiko Kodama, Toru Okamoto, Makoto Tokunaga, Hiroko Shimura, Nancy A Jenkins

Biochem Biophys Res Commun· May 2021

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Promoterless Transposon Mutagenesis Drives Solid Cancers via Tumor Suppressor Inactivation.
Aziz Aiderus, Ana M Contreras-Sandoval, Amanda L Meshey, Justin Y Newberg, Jerrold M Ward, Nancy A Jenkins

Cancers (Basel)· January 2021

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is a critical regulator of adult long-term hematopoietic stem cell quiescence.
Kristbjorn O Gudmundsson, Nhu Nguyen, Kevin Oakley, Yufen Han, Bjorg Gudmundsdottir, Nancy A Jenkins

Proc Natl Acad Sci U S A· December 2020

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MRTFB suppresses colorectal cancer development through regulating SPDL1 and MCAM.
Takahiro Kodama, Teresa A Marian, Hubert Lee, Michiko Kodama, Jian Li, Nancy A Jenkins

Proc Natl Acad Sci U S A· November 2019

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Author Correction: A recellularized human colon model identifies cancer driver genes.
Huanhuan Joyce Chen, Zhubo Wei, Jian Sun, Asmita Bhattacharya, David J Savage, Nancy A Jenkins

Nat Biotechnol· July 2019

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CRISPR-Cas9-mediated gene knockout in intestinal tumor organoids provides functional validation for colorectal cancer driver genes.
Haruna Takeda, Shiho Kataoka, Mizuho Nakayama, Mohamed A E Ali, Hiroko Oshima, Nancy A Jenkins

Proc Natl Acad Sci U S A· July 2019

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The Roles of Initiating Truncal Mutations in Human Cancers: The Order of Mutations and Tumor Cell Type Matters.
Arnold J Levine, Nancy A Jenkins, Neal G Copeland

Cancer Cell· January 2019

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Molecular profiling of nonalcoholic fatty liver disease-associated hepatocellular carcinoma using SB transposon mutagenesis.
Takahiro Kodama, Jing Yi, Justin Y Newberg, Jean C Tien, Hao Wu, Nancy A Jenkins

Proc Natl Acad Sci U S A· October 2018

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SB Driver Analysis: a Sleeping Beauty cancer driver analysis framework for identifying and prioritizing experimentally actionable oncogenes and tumor suppressors.
Justin Y Newberg, Michael A Black, Nancy A Jenkins, Neal G Copeland, Karen M Mann

Nucleic Acids Res· September 2018

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Creation of a myosin Va-TAP-tagged mouse and identification of potential myosin Va-interacting proteins in the cerebellum.
Christopher J Alexander, Wolfgang Wagner, Neal G Copeland, Nancy A Jenkins, John A Hammer

Cytoskeleton (Hoboken)· September 2018

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Stability and Function of Hippocampal Mossy Fiber Synapses Depend on .
Elodie De Bruyckere, Ruth Simon, Sigrun Nestel, Bernd Heimrich, Dennis Kätzel, Nancy A Jenkins

Front Mol Neurosci· April 2018

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SBCDDB: Sleeping Beauty Cancer Driver Database for gene discovery in mouse models of human cancers.
Justin Y Newberg, Karen M Mann, Michael B Mann, Nancy A Jenkins, Neal G Copeland

Nucleic Acids Res· January 2018

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p120-Catenin is an obligate haploinsufficient tumor suppressor in intestinal neoplasia.
Sarah P Short, Jumpei Kondo, Whitney G Smalley-Freed, Haruna Takeda, Michael R Dohn, Nancy A Jenkins

J Clin Invest· December 2017

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Identification of New Tumor Suppressor Genes in Triple-Negative Breast Cancer.
Roberto Rangel, Liliana Guzman-Rojas, Takahiro Kodama, Michiko Kodama, Justin Y Newberg, Nancy A Jenkins

Cancer Res· August 2017

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In vivo loss-of-function screens identify KPNB1 as a new druggable oncogene in epithelial ovarian cancer.
Michiko Kodama, Takahiro Kodama, Justin Y Newberg, Hiroyuki Katayama, Makoto Kobayashi, Nancy A Jenkins

Proc Natl Acad Sci U S A· August 2017

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Transposon insertional mutagenesis in mice identifies human breast cancer susceptibility genes and signatures for stratification.
Liming Chen, Piroon Jenjaroenpun, Andrea Mun Ching Pillai, Anna V Ivshina, Ghim Siong Ow, Nancy A Jenkins

Proc Natl Acad Sci U S A· March 2017

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