Publications by authors named "Nancy R Manley"

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Coordinated changes in stromal and hematopoietic cells that define the perinatal to juvenile transition in the mouse thymus.
Anusha Vasudev, Colin R Moore, Aparna Calindi, Seung Woo Kang, Bryan R Helm, Nancy R Manley

Cell Rep· December 2025

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Premature thymic involution in young Foxn1lacz mutant mice causes peripheral T cell phenotypes similar to aging-induced immunosenescence.
Shiyun Xiao, Seung Woo Kang, Kimberly E Oliva, Wen Zhang, Kimberly D Klonowski, Nancy R Manley

J Immunol· October 2025

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Insulin-like growth factor 2 as a driving force for exponential expansion and differentiation of the neonatal thymus.
Seung Woo Kang, Bryan R Helm, Yu Wang, Shiyun Xiao, Wen Zhang, Nancy R Manley

Development· April 2025

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Dicer-Mediated mTORC1 Signaling and Parathyroid Gland Integrity and Function.
Alia Hassan, Nareman Khalaily, Rachel Kilav-Levin, Barbara Del Castello, Nancy Ruth Manley

J Am Soc Nephrol· September 2024

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Age-related epithelial defects limit thymic function and regeneration.
Anastasia I Kousa, Lorenz Jahn, Kelin Zhao, Angel E Flores, Dante Acenas, Nancy R Manley

Nat Immunol· September 2024

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Mechanisms underlying the direct programming of mouse embryonic fibroblasts to thymic epithelial cells by FOXN1.
Zhongyao Ma, Seung Woo Kang, Brian G Condie, Nancy R Manley

Development· July 2024

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Lin28 regulates thymic growth and involution and correlates with MHCII expression in thymic epithelial cells.
Shiyun Xiao, Wen Zhang, Jie Li, Nancy R Manley

Front Immunol· November 2023

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Foxn1 overexpression promotes thymic epithelial progenitor cell proliferation and mTEC maintenance, but does not prevent thymic involution.
Jie Li, Lucas P Wachsmuth, Shiyun Xiao, Brian G Condie, Nancy R Manley

Development· April 2023

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Novel murine model reveals an early role for pertussis toxin in disrupting neonatal immunity to .
Colleen J Sedney, Amanda Caulfield, Kaylan K Dewan, Uriel Blas-Machado, Maiya Callender, Nancy R Manley

Front Immunol· March 2023

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Thymic epithelial cells require lipid kinase Vps34 for CD4 but not CD8 T cell selection.
J Luke Postoak, Wenqiang Song, Guan Yang, Xingyi Guo, Shiyun Xiao, Nancy R Manley

J Exp Med· October 2022

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NOTCH1 signaling establishes the medullary thymic epithelial cell progenitor pool during mouse fetal development.
Jie Li, Julie Gordon, Edward L Y Chen, Shiyun Xiao, Luying Wu, Nancy R Manley

Development· June 2020

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Embryology of the Parathyroid Glands.
Kristen Peissig, Brian G Condie, Nancy R Manley

Endocrinol Metab Clin North Am· December 2018

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Polycomb Repressive Complex 2 is essential for development and maintenance of a functional TEC compartment.
Nandini Singarapu, Keyue Ma, Kaitlin A G Reeh, Jianjun Shen, Jessica N Lancaster, Nancy R Manley

Sci Rep· September 2018

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Predicted miRNA-mRNA-mediated posttranscriptional control associated with differences in cervical and thoracic thymus function.
Amanda F Assis, Jie Li, Paula B Donate, Janaína A Dernowsek, Nancy R Manley

Mol Immunol· July 2018

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Thymic epithelial cell-derived signals control B progenitor formation and proliferation in the thymus by regulating Let-7 and Arid3a.
Shiyun Xiao, Wen Zhang, Nancy R Manley

PLoS One· May 2018

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Thymic B cell development is controlled by the B potential of progenitors via both hematopoietic-intrinsic and thymic microenvironment-intrinsic regulatory mechanisms.
Shiyun Xiao, Wen Zhang, Nancy R Manley

PLoS One· May 2018

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Production of BMP4 by endothelial cells is crucial for endogenous thymic regeneration.
Tobias Wertheimer, Enrico Velardi, Jennifer Tsai, Kirsten Cooper, Shiyun Xiao, Nancy R Manley

Sci Immunol· January 2018

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Sublethal Total Body Irradiation Causes Long-Term Deficits in Thymus Function by Reducing Lymphoid Progenitors.
Shiyun Xiao, Ivo D Shterev, Wen Zhang, Lauren Young, Jae-Hung Shieh, Nancy R Manley

J Immunol· October 2017

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Late Effects of Exposure to Ionizing Radiation and Age on Human Thymus Morphology and Function.
Reiko Ito, Laura P Hale, Susan M Geyer, Jie Li, Andrew Sornborger, Nancy R Manley

Radiat Res· May 2017

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MiCASA is a new method for quantifying cellular organization.
Andrew Sornborger, Jie Li, Cullen Timmons, Floria Lupu, Jonathan Eggenschwiler, Nancy R Manley

Nat Commun· May 2017

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Tissue-specific roles for sonic hedgehog signaling in establishing thymus and parathyroid organ fate.
Virginia E Bain, Julie Gordon, John D O'Neil, Isaias Ramos, Ellen R Richie, Nancy R Manley

Development· November 2016

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Temporal and spatial requirements for Hoxa3 in mouse embryonic development.
Jena L Chojnowski, Heidi A Trau, Kyoko Masuda, Nancy R Manley

Dev Biol· July 2016

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Optimization of Single- and Dual-Color Immunofluorescence Protocols for Formalin-Fixed, Paraffin-Embedded Archival Tissues.
Junko Kajimura, Reiko Ito, Nancy R Manley, Laura P Hale

J Histochem Cytochem· February 2016

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Construction of a functional thymic microenvironment from pluripotent stem cells for the induction of central tolerance.
Nicholas Bredenkamp, Xin Jin, Dong Liu, Kathy E O'Neill, Nancy R Manley

Regen Med· January 2016

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Multiple roles for HOXA3 in regulating thymus and parathyroid differentiation and morphogenesis in mouse.
Jena L Chojnowski, Kyoko Masuda, Heidi A Trau, Kirk Thomas, Mario Capecchi, Nancy R Manley

Development· October 2014

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