Publications by authors named "Natalia Issaeva"

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Bridging EGFR/TGF-β Signaling to Bypass Resistance to Immune Checkpoint Blockade.
Noura J Choudhury, Aditi Kothari, Christine M Bestvina, Natalia Issaeva

Clin Cancer Res· November 2025

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Molecular characterization of the salivary adenoid cystic carcinoma immune landscape by anatomic subsites.
Jason Tasoulas, Travis P Schrank, Harish Bharambe, Jay Mehta, Steven Johnson, Natalia Issaeva

Sci Rep· July 2024

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De-Escalated Therapy and Early Treatment of Recurrences in HPV-Associated Head and Neck Cancer: The Potential for Biomarkers to Revolutionize Personalized Therapy.
Wendell G Yarbrough, Travis P Schrank, Barbara A Burtness, Natalia Issaeva

Viruses· March 2024

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Noncanonical HPV carcinogenesis drives radiosensitization of head and neck tumors.
Travis P Schrank, Aditi Kothari, William H Weir, Wesley H Stepp, Hina Rehmani, Natalia Issaeva

Proc Natl Acad Sci U S A· August 2023

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Comprehensive Viral Genotyping Reveals Prognostic Viral Phylogenetic Groups in HPV16-Associated Squamous Cell Carcinoma of the Oropharynx.
Travis P Schrank, Lee Landess, Wesley H Stepp, Hina Rehmani, William H Weir, Natalia Issaeva

Mol Cancer Res· October 2022

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Development of a Novel Molecular Test for Determining HPV Integration Status in HPV-Positive Oropharynx Cancers.
Wesley H Stepp, T Danielle Samulski, Trevor G Hackman, Natalia Issaeva, Wendell G Yarbrough

JAMA Otolaryngol Head Neck Surg· October 2022

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Exploring ABOBEC3A and APOBEC3B substrate specificity and their role in HPV positive head and neck cancer.
Christina Papini, Zechen Wang, Shalley N Kudalkar, Travis Parke Schrank, Su Tang, Natalia Issaeva

iScience· October 2022

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Erratum: Exploring APOBEC3A and APOBEC3B substrate specificity and their role in HPV positive head and neck cancer.
Christina Papini, Zechen Wang, Shalley N Kudalkar, Travis Parke Schrank, Su Tang, Natalia Issaeva

iScience· October 2022

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NF-κB over-activation portends improved outcomes in HPV-associated head and neck cancer.
Travis P Schrank, Andrew C Prince, Tejas Sathe, Xiaowei Wang, Xinyi Liu, Natalia Issaeva

Oncotarget· September 2022

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Direct Comparison of HPV16 Viral Genomic Integration, Copy Loss, and Structural Variants in Oropharyngeal and Uterine Cervical Cancers Reveal Distinct Relationships to E2 Disruption and Somatic Alteration.
Travis P Schrank, Sulgi Kim, Hina Rehmani, Aditi Kothari, Di Wu, Natalia Issaeva

Cancers (Basel)· September 2022

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Novel Allosteric Mechanism of Dual p53/MDM2 and p53/MDM4 Inhibition by a Small Molecule.
Vera V Grinkevich, Aparna Vema, Karin Fawkner, Natalia Issaeva, Virginia Andreotti

Front Mol Biosci· June 2022

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Genomic heterogeneity and copy number variant burden are associated with poor recurrence-free survival and 11q loss in human papillomavirus-positive squamous cell carcinoma of the oropharynx.
Travis P Schrank, Nicholas Lenze, Lee P Landess, Alan Hoyle, Joel Parker, Natalia Issaeva

Cancer· August 2021

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Dual Targeting of Chromatin Stability By The Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Shows Significant Preclinical Efficacy in Neuroblastoma.
Lin Xiao, Klaartje Somers, Jayne Murray, Ruby Pandher, Mawar Karsa, Natalia Issaeva

Clin Cancer Res· August 2021

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Global Genome Demethylation Causes Transcription-Associated DNA Double Strand Breaks in HPV-Associated Head and Neck Cancer Cells.
Michael Hajek, Asel Biktasova, Andrew Sewell, Cyril Gary, Paul Cantalupo, Natalia Issaeva

Cancers (Basel)· December 2020

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EGFR in head and neck squamous cell carcinoma: exploring possibilities of novel drug combinations.
Hina S Rehmani, Natalia Issaeva

Ann Transl Med· July 2020

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NSD1 mutations by HPV status in head and neck cancer: differences in survival and response to DNA-damaging agents.
Cassie Pan, Said Izreig, Wendell G Yarbrough, Natalia Issaeva

Cancers Head Neck· July 2019

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Combined Aurora Kinase A (AURKA) and WEE1 Inhibition Demonstrates Synergistic Antitumor Effect in Squamous Cell Carcinoma of the Head and Neck.
Jong Woo Lee, Janaki Parameswaran, Teresa Sandoval-Schaefer, Kyung Jin Eoh, Dong-Hua Yang, Natalia Issaeva

Clin Cancer Res· June 2019

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APOBEC-induced mutations and their cancer effect size in head and neck squamous cell carcinoma.
Vincent L Cannataro, Stephen G Gaffney, Tomoaki Sasaki, Natalia Issaeva, Nicholas K S Grewal

Oncogene· May 2019

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p53 Signaling in Cancers.
Natalia Issaeva

Cancers (Basel)· March 2019

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HPV-driven oropharyngeal cancer: current knowledge of molecular biology and mechanisms of carcinogenesis.
Cassie Pan, Natalia Issaeva, Wendell G Yarbrough

Cancers Head Neck· December 2018

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Genomic and Transcriptomic Characterization Links Cell Lines with Aggressive Head and Neck Cancers.
Hui Cheng, Xinping Yang, Han Si, Anthony D Saleh, Wenming Xiao, Natalia Issaeva

Cell Rep· October 2018

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Attenuated TRAF3 Fosters Activation of Alternative NF-κB and Reduced Expression of Antiviral Interferon, TP53, and RB to Promote HPV-Positive Head and Neck Cancers.
Jialing Zhang, Tony Chen, Xinping Yang, Hui Cheng, Stephan S Späth, Natalia Issaeva

Cancer Res· August 2018

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Advances in biomarkers and treatment strategies for HPV-associated head and neck cancer.
Cassie Pan, Wendell G Yarbrough, Natalia Issaeva

Oncoscience· May 2018

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Demethylation Therapy as a Targeted Treatment for Human Papillomavirus-Associated Head and Neck Cancer.
Asel Biktasova, Michael Hajek, Andrew Sewell, Cyril Gary, Gary Bellinger, Natalia Issaeva

Clin Cancer Res· December 2017

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Reactivation of mutant p53 and induction of apoptosis in human tumor cells by maleimide analogs.
Vladimir J N Bykov, Natalia Issaeva, Nicole Zache, Alexandre Shilov, Monica Hultcrantz

J Biol Chem· December 2017

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