Publications by authors named "Natalie Stratton"

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Prolonged Cancer Control With Adagrasib in Patients With Metastatic, -Mutated NSCLC After Sotorasib-Induced Hepatotoxicity: A Case Report.
Natalie Stratton, Jonathan Thompson

JTO Clin Res Rep· April 2024

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Implication of in Accelerating Tumor Development and Therapeutically Targeting ZNF217-Induced PI3K-AKT Signaling for the Treatment of Metastatic Osteosarcoma.
Branden A Smeester, Garrett M Draper, Nicholas J Slipek, Alex T Larsson, Natalie Stratton

Mol Cancer Ther· December 2020

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PLX3397 treatment inhibits constitutive CSF1R-induced oncogenic ERK signaling, reduces tumor growth, and metastatic burden in osteosarcoma.
Branden A Smeester, Nicholas J Slipek, Emily J Pomeroy, Kanut Laoharawee, Sara H Osum, Natalie Stratton

Bone· July 2020

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Discovery of a Series of 3-Cinnoline Carboxamides as Orally Bioavailable, Highly Potent, and Selective ATM Inhibitors.
Bernard Barlaam, Elaine Cadogan, Andrew Campbell, Nicola Colclough, Allan Dishington, Natalie Stratton

ACS Med Chem Lett· August 2018

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The Identification of Potent, Selective, and Orally Available Inhibitors of Ataxia Telangiectasia Mutated (ATM) Kinase: The Discovery of AZD0156 (8-{6-[3-(Dimethylamino)propoxy]pyridin-3-yl}-3-methyl-1-(tetrahydro-2 H-pyran-4-yl)-1,3-dihydro-2 H-imidazo[4,5- c]quinolin-2-one).
Kurt G Pike, Bernard Barlaam, Elaine Cadogan, Andrew Campbell, Yingxue Chen, Natalie Stratton

J Med Chem· May 2018

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Potent and selective bivalent inhibitors of BET bromodomains.
Michael J Waring, Huawei Chen, Alfred A Rabow, Graeme Walker, Romel Bobby, Natalie Stratton

Nat Chem Biol· December 2016

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Optimization of a Series of Bivalent Triazolopyridazine Based Bromodomain and Extraterminal Inhibitors: The Discovery of (3R)-4-[2-[4-[1-(3-Methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-4-piperidyl]phenoxy]ethyl]-1,3-dimethyl-piperazin-2-one (AZD5153).
Robert H Bradbury, Rowena Callis, Gregory R Carr, Huawei Chen, Edwin Clark, Natalie Stratton

J Med Chem· September 2016

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Patient Characteristics by Type of Hypersexuality Referral: A Quantitative Chart Review of 115 Consecutive Male Cases.
Katherine S Sutton, Natalie Stratton, Jennifer Pytyck, Nathan J Kolla, James M Cantor

J Sex Marital Ther· May 2016

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AZD3514: a small molecule that modulates androgen receptor signaling and function in vitro and in vivo.
Sarah A Loddick, Sarah J Ross, Andrew G Thomason, David M Robinson, Graeme E Walker, Natalie C Stratton

Mol Cancer Ther· September 2013

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Discovery of AZD3514, a small-molecule androgen receptor downregulator for treatment of advanced prostate cancer.
Robert H Bradbury, David G Acton, Nicola L Broadbent, A Nigel Brooks, Gregory R Carr, Natalie C Stratton

Bioorg Med Chem Lett· April 2013

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