Publications by authors named "Nathan Ponzar"

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Mechanistic basis of activation and inhibition of protein disulfide isomerase by allosteric antithrombotic compounds.
Nathan Ponzar, Mathivanan Chinnaraj, Anna Pagotto, Vincenzo De Filippis, Robert Flaumenhaft

J Thromb Haemost· February 2025

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Sulfenylation links oxidative stress to protein disulfide isomerase oxidase activity and thrombus formation.
Moua Yang, Joyce Chiu, Christina Scartelli, Nathan Ponzar, Sachin Patel

J Thromb Haemost· August 2023

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Probing the conformational dynamics of thiol-isomerases using non-canonical amino acids and single-molecule FRET.
Nathan Ponzar, Nicola Pozzi

Methods· June 2023

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Predicted structure of the hepatitis B virus polymerase reveals an ancient conserved protein fold.
Razia Tajwar, Daniel P Bradley, Nathan L Ponzar, John E Tavis

Protein Sci· October 2022

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Alpha-hydroxytropolones are noncompetitive inhibitors of human RNase H1 that bind to the active site and modulate substrate binding.
Nathan L Ponzar, Razia Tajwar, Nicola Pozzi, John E Tavis

J Biol Chem· April 2022

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Effects of Troponoids on Mitochondrial Function and Cytotoxicity.
Daniel P Bradley, Austin T O'Dea, Molly E Woodson, Qilan Li, Nathan L Ponzar

Antimicrob Agents Chemother· January 2022

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A mid-throughput HBV replication inhibition assay capable of detecting ribonuclease H inhibitors.
Qilan Li, Tiffany C Edwards, Nathan L Ponzar, John E Tavis

J Virol Methods· June 2021

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Shedding light on RNaseH: a promising target for hepatitis B virus (HBV).
Tiffany C Edwards, Nathan L Ponzar, John E Tavis

Expert Opin Ther Targets· July 2019

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Efficacy of hepatitis B virus ribonuclease H inhibitors, a new class of replication antagonists, in FRG human liver chimeric mice.
Kelly R Long, Elena Lomonosova, Qilan Li, Nathan L Ponzar, Juan A Villa

Antiviral Res· January 2018

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