Publications by authors named "Nathan Ryan"

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PI3Kγ inhibition drives M1 macrophage differentiation and synergizes with PD-L1 blockade to improve survival in poorly immunogenic head and neck squamous cell carcinoma.
Pete P Jordanides, Sushmitha Jagadeesha, Puja Upadhaya, Nathan M Ryan, Kelvin Anderson

Cancer Biol Ther· December 2026

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Vaccination against Onchocerca volvulus induces IgG-mediated protective immunity dependent on neutrophils and complement.
Nathan M Ryan, Jessica A Hess, Mohini Nakhale, Annabel A Ferguson, William Stump

NPJ Vaccines· October 2025

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Inhibition of head and neck squamous cell carcinoma by Bruton's tyrosine kinase inhibitor ibrutinib is associated with reduction of immunosuppressive T cells.
Anna R Bopp, Felipe F Lamenza, Puja Upadhaya, Nathan M Ryan, Natalie Kazmierowicz

Cancer Immunol Immunother· May 2025

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Targeting macrophage migration inhibitory factor to inhibit T cell immunosuppression in the tumor microenvironment and improve cancer outcomes in head and neck squamous cell carcinoma.
S Hasan Pracha, Suvekshya Shrestha, Nathan Ryan, Puja Upadhaya, Felipe F Lamenza

Oral Oncol· January 2025

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Host derived macrophage migration inhibitory factor expression attenuates anti-tumoral immune cell accumulation and promotes immunosuppression in the tumor microenvironment of head and neck squamous cell carcinoma.
Nathan Ryan, Felipe Lamenza, Suvekshya Shrestha, Puja Upadhaya, Anna Springer

Biochim Biophys Acta Mol Basis Dis· October 2024

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Searching for the unexpected - understanding information-seeking behaviours of people new to prison visits.
Nicole R Ryan, Nathan C Ryan

Psychiatr Psychol Law· January 2024

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Inducible TgfbR1 and Pten deletion in a model of tongue carcinogenesis and chemoprevention.
Felipe F Lamenza, Nathan M Ryan, Puja Upadhaya, Arham Siddiqui, Pete P Jordanides

Cancer Gene Ther· August 2023

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Adjuvanted Fusion Protein Vaccine Induces Durable Immunity to in Mice and Non-Human Primates.
Nathan M Ryan, Jessica A Hess, Erica J Robertson, Nancy Tricoche, Cheri Turner

Vaccines (Basel)· July 2023

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Ionizing Radiation Reduces Head and Neck Squamous Cell Carcinoma Cell Viability and Is Associated with Predictive Tumor-Specific T Cell Responses.
Puja Upadhaya, Nathan Ryan, Peyton Roth, Travis Pero, Felipe Lamenza

Cancers (Basel)· June 2023

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STAT1 is regulated by TRIM24 and promotes immunosuppression in head and neck squamous carcinoma cells, but enhances T cell antitumour immunity in the tumour microenvironment.
Kelvin Anderson, Nathan Ryan, Divya Nedungadi, Felipe Lamenza, Michael Swingler

Br J Cancer· September 2022

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Black raspberry extract inhibits regulatory T-cell activity in a murine model of head and neck squamous cell carcinoma chemoprevention.
Nathan M Ryan, Felipe F Lamenza, Puja Upadhaya, Hasan Pracha, Anna Springer

Front Immunol· August 2022

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Modulation of the oral glucocorticoid system during black raspberry mediated oral cancer chemoprevention.
Divya Nedungadi, Nathan Ryan, Kelvin Anderson, Felipe F Lamenza, Pete P Jordanides

Carcinogenesis· February 2022

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Cross Talk between ARF1 and RhoA Coordinates the Formation of Cytoskeletal Scaffolds during Chlamydia Infection.
Adam Haines, Jordan Wesolowski, Nathan M Ryan, Tiago Monteiro-Brás, Fabienne Paumet

mBio· December 2021

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The IL-33/ST2 Axis in Immune Responses Against Parasitic Disease: Potential Therapeutic Applications.
Nathan Ryan, Kelvin Anderson, Greta Volpedo, Sanjay Varikuti, Monika Satoskar

Front Cell Infect Microbiol· June 2021

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Inhibition of PI3K Isoform p110γ Increases Both Anti-Tumor and Immunosuppressive Responses to Aggressive Murine Head and Neck Squamous Cell Carcinoma with Low Immunogenicity.
Kelvin Anderson, Nathan Ryan, Anastasia Alkhimovitch, Arham Siddiqui, Steve Oghumu

Cancers (Basel)· February 2021

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Onchocerca volvulus bivalent subunit vaccine induces protective immunity in genetically diverse collaborative cross recombinant inbred intercross mice.
Nathan M Ryan, Jessica A Hess, Fernando Pardo-Manuel de Villena, Benjamin E Leiby, Ayako Shimada

NPJ Vaccines· January 2021

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Immune Suppression Mediated by STAT4 Deficiency Promotes Lymphatic Metastasis in HNSCC.
Kelvin Anderson, Nathan Ryan, Greta Volpedo, Sanjay Varikuti, Abhay R Satoskar

Front Immunol· October 2020

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Black Raspberries and Protocatechuic Acid Mitigate DNFB-Induced Contact Hypersensitivity by Down-Regulating Dendritic Cell Activation and Inhibiting Mediators of Effector Responses.
Kelvin Anderson, Nathan Ryan, Arham Siddiqui, Travis Pero, Greta Volpedo

Nutrients· June 2020

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Measurement of Monoclonal Immunoglobulin Protein Concentration in Serum Protein Electrophoresis: Comparison of Automated vs Manual/Human Readings.
Alex Clavijo, Nathan Ryan, Hongyan Xu, Gurmukh Singh

Lab Med· May 2020

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STAT1 inhibits T-cell exhaustion and myeloid derived suppressor cell accumulation to promote antitumor immune responses in head and neck squamous cell carcinoma.
Nathan Ryan, Kelvin Anderson, Greta Volpedo, Omar Hamza, Sanjay Varikuti

Int J Cancer· March 2020

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Resection of an Inferior Vena Cava Leiomyosarcoma.
Andrew Harner, Jane Chung, Thuy Pham, Nathan Ryan, Gautam Agarwal

Am Surg· September 2019

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Metabolic Regulation of Glycolysis and AMP Activated Protein Kinase Pathways during Black Raspberry-Mediated Oral Cancer Chemoprevention.
Thomas J Knobloch, Nathan M Ryan, Lei Bruschweiler-Li, Cheng Wang, Matthew C Bernier

Metabolites· July 2019

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Role of mast cells in the generation of a T-helper type 2 dominated anti-helminthic immune response.
Nathan M Ryan, Steve Oghumu

Biosci Rep· February 2019

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Nanoparticulate drug delivery systems for the treatment of neglected tropical protozoan diseases.
Greta Volpedo, Lourena Costa, Nathan Ryan, Gregory Halsey, Abhay Satoskar

J Venom Anim Toxins Incl Trop Dis· February 2019

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Host-Directed Drug Therapies for Neglected Tropical Diseases Caused by Protozoan Parasites.
Sanjay Varikuti, Bijay Kumar Jha, Greta Volpedo, Nathan M Ryan, Gregory Halsey

Front Microbiol· November 2018

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