Publications by authors named "Nathaniel Sharp"

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Evolutionary responses to increased opportunity for sexual selection in yeast.
Linnea Sandell, Anna L Bazzicalupo, Sarah P Otto, Nathaniel P Sharp

bioRxiv· November 2025

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The effect of spontaneous mutations on copy number and copper tolerance in .
Rohan Sohoni, Gillian G Schatz, Nathaniel P Sharp

bioRxiv· November 2025

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Contrasting mutation patterns in haploid and diploid cells from two yeast species.
Kevin Bao, Rutuja Gupte, Neil Braker, Nathaniel P Sharp

bioRxiv· October 2025

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Meiotic double strand DNA breaks and spontaneous mutation in .
Rob Melde, Austin Daigle, JoHanna Abraham, Nathaniel Sharp

bioRxiv· October 2025

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Quantitative genetics of trauma induced mortality in .
Gwanwoou Yun, Ronchen Liu, Nathaniel P Sharp

bioRxiv· October 2025

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Fitness consequences of sex chromosome aneuploidy in Drosophila melanogaster.
Elizabeth R Makovec, Caitlin C Kestell, Kayla K Janke, Ethan J Carter, Aaron P Ragsdale, Nathaniel P Sharp

PLoS Genet· June 2025

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On the rate of aneuploidy reversion in a wild yeast model.
James Hose, Qi Zheng, Nathaniel P Sharp, Audrey P Gasch

Genetics· February 2025

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Yeast mutation rates in alternative carbon sources reflect the influence of reactive oxygen species.
Keerthana Thota, Jacob D Fredette-Roman, Nathaniel P Sharp

MicroPubl Biol· February 2025

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Sex-specific viability effects of mutations in Drosophila melanogaster.
Robert H Melde, JoHanna M Abraham, Maryn R Ugolini, Madison P Castle, Molly M Fjalstad, Nathaniel P Sharp

Evolution· October 2024

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Mutations in yeast are deleterious on average regardless of the degree of adaptation to the testing environment.
Kevin Bao, Brant R Strayer, Neil P Braker, Alexandra A Chan, Nathaniel P Sharp

Proc Biol Sci· June 2024

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Contribution of Spontaneous Mutations to Quantitative and Molecular Variation at the Highly Repetitive rDNA Locus in Yeast.
Nathaniel P Sharp, Denise R Smith, Gregory Driscoll, Kexin Sun, Catherine M Vickerman

Genome Biol Evol· October 2023

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Recent insights into the evolution of mutation rates in yeast.
Robert H Melde, Kevin Bao, Nathaniel P Sharp

Curr Opin Genet Dev· October 2022

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Are mutations usually deleterious? A perspective on the fitness effects of mutation accumulation.
Kevin Bao, Robert H Melde, Nathaniel P Sharp

Evol Ecol· October 2022

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Mutations matter even if proteins stay the same.
Nathaniel Sharp

Nature· June 2022

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Fitness Effects of Mutations: An Assessment of PROVEAN Predictions Using Mutation Accumulation Data.
Linnea Sandell, Nathaniel P Sharp

Genome Biol Evol· January 2022

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The population genetics of ploidy change in unicellular fungi.
Aleeza C Gerstein, Nathaniel P Sharp

FEMS Microbiol Rev· September 2021

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No evidence of positive assortative mating for genetic quality in fruit flies.
Nathaniel P Sharp, Michael C Whitlock

Proc Biol Sci· October 2019

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An experimental test of the mutation-selection balance model for the maintenance of genetic variance in fitness components.
Nathaniel P Sharp, Aneil F Agrawal

Proc Biol Sci· November 2018

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The genome-wide rate and spectrum of spontaneous mutations differ between haploid and diploid yeast.
Nathaniel P Sharp, Linnea Sandell, Christopher G James, Sarah P Otto

Proc Natl Acad Sci U S A· May 2018

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Evolution: Zeroing In on the Rate of Genome Doubling.
Nathaniel P Sharp, Sarah P Otto

Curr Biol· April 2018

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Local Adaptation Interacts with Expansion Load during Range Expansion: Maladaptation Reduces Expansion Load.
Kimberly J Gilbert, Nathaniel P Sharp, Amy L Angert, Gina L Conte, Jeremy A Draghi

Am Nat· April 2017

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Evolution of sex: Using experimental genomics to select among competing theories.
Nathaniel P Sharp, Sarah P Otto

Bioessays· August 2016

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Low Genetic Quality Alters Key Dimensions of the Mutational Spectrum.
Nathaniel P Sharp, Aneil F Agrawal

PLoS Biol· March 2016

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Sexual antagonism for resistance and tolerance to infection in Drosophila melanogaster.
Crystal M Vincent, Nathaniel P Sharp

Proc Biol Sci· August 2014

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Sensitivity of the distribution of mutational fitness effects to environment, genetic background, and adaptedness: a case study with Drosophila.
Alethea D Wang, Nathaniel P Sharp, Aneil F Agrawal

Evolution· March 2014

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