Publications by authors named "Nathaniel Traaseth"

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Quantification of Membrane Protein Conformational Free Energy from Mutations and a Single Atom.
Belen Ramirez-Cordero, Nathaniel J Traaseth

J Am Chem Soc· September 2025

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Small molecule inhibitors of the NorA multidrug efflux pump potentiate antibiotic activity by binding the outward-open conformation.
Janine L Gray, Elizabeth V K Ledger, Tiffany Suwatthee, Thomas J Burden, Konstantina Arvaniti, Nathaniel J Traaseth

bioRxiv· August 2025

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A fiducial-assisted strategy compatible with resolving small MFS transporter structures in multiple conformations using cryo-EM.
Pujun Xie, Yan Li, Gaëlle Lamon, Huihui Kuang, Da-Neng Wang, Nathaniel J Traaseth

Nat Commun· January 2025

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Proton-coupled transport mechanism of the efflux pump NorA.
Jianping Li, Yan Li, Akiko Koide, Huihui Kuang, Victor J Torres, Nathaniel J Traaseth

Nat Commun· May 2024

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Dynamics underlie the drug recognition mechanism by the efflux transporter EmrE.
Jianping Li, Ampon Sae Her, Alida Besch, Belen Ramirez-Cordero, Maureen Crames, Nathaniel J Traaseth

Nat Commun· May 2024

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Gatekeeper mutations activate FGF receptor tyrosine kinases by destabilizing the autoinhibited state.
Alida Besch, William M Marsiglia, Moosa Mohammadi, Yingkai Zhang, Nathaniel J Traaseth

Proc Natl Acad Sci U S A· February 2023

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Inhibition of RAS-driven signaling and tumorigenesis with a pan-RAS monobody targeting the Switch I/II pocket.
Lauren Wallon, Imran Khan, Kai Wen Teng, Akiko Koide, Mariyam Zuberi, Nathaniel J Traaseth

Proc Natl Acad Sci U S A· October 2022

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Structural basis for inhibition of the drug efflux pump NorA from Staphylococcus aureus.
Douglas N Brawley, David B Sauer, Jianping Li, Xuhui Zheng, Akiko Koide, Nathaniel J Traaseth

Nat Chem Biol· July 2022

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Programmed Supramolecular Assemblies Using Orthogonal Pairs of Heterodimeric Coiled Coil Peptides.
Linhai Jiang, Xiaobing Zuo, Jianping Li, Nathaniel J Traaseth, Kent Kirshenbaum

Angew Chem Int Ed Engl· July 2022

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Asymmetric protonation of glutamate residues drives a preferred transport pathway in EmrE.
Jianping Li, Ampon Sae Her, Nathaniel J Traaseth

Proc Natl Acad Sci U S A· October 2021

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Site-specific resolution of anionic residues in proteins using solid-state NMR spectroscopy.
Jianping Li, Ampon Sae Her, Nathaniel J Traaseth

J Biomol NMR· July 2020

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Molecular basis for receptor tyrosine kinase A-loop tyrosine transphosphorylation.
Lingfeng Chen, William M Marsiglia, Huaibin Chen, Joseph Katigbak, Hediye Erdjument-Bromage, Nathaniel J Traaseth

Nat Chem Biol· March 2020

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A CURE Biochemistry Laboratory Module to Study Protein-Protein Interactions by NMR Spectroscopy.
William M Marsiglia, Rohini Qamra, Kimberly M Jackson, Nathaniel J Traaseth

J Chem Educ· February 2020

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Inducing conformational preference of the membrane protein transporter EmrE through conservative mutations.
Maureen Leninger, Ampon Sae Her, Nathaniel J Traaseth

Elife· October 2019

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A Conserved Allosteric Pathway in Tyrosine Kinase Regulation.
William M Marsiglia, Joseph Katigbak, Sijin Zheng, Moosa Mohammadi, Yingkai Zhang, Nathaniel J Traaseth

Structure· August 2019

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Magnetization transfer in liposome and proteoliposome samples that mimic the protein and lipid composition of myelin.
Weiqi Yang, Jae-Seung Lee, Maureen Leninger, Johannes Windschuh, Nathaniel J Traaseth

NMR Biomed· July 2019

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Afterglow Solid-State NMR Spectroscopy.
Gili Abramov, Nathaniel J Traaseth

Methods Mol Biol· July 2018

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NMR Spectroscopy Approach to Study the Structure, Orientation, and Mechanism of the Multidrug Exporter EmrE.
Maureen Leninger, Nathaniel J Traaseth

Methods Mol Biol· July 2018

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Structural and kinetic insights into stimulation of RppH-dependent RNA degradation by the metabolic enzyme DapF.
Ang Gao, Nikita Vasilyev, Daniel J Luciano, Rose Levenson-Palmer, Jamie Richards, Nathaniel J Traaseth

Nucleic Acids Res· July 2018

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Multiple frequency saturation pulses reduce CEST acquisition time for quantifying conformational exchange in biomolecules.
Maureen Leninger, William M Marsiglia, Alexej Jerschow, Nathaniel J Traaseth

J Biomol NMR· May 2018

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Assessing Interactions Between a Polytopic Membrane Protein and Lipid Bilayers Using Differential Scanning Calorimetry and Solid-State NMR.
James R Banigan, Maureen Leninger, Ampon Sae Her, Nathaniel J Traaseth

J Phys Chem B· March 2018

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Elucidation of a four-site allosteric network in fibroblast growth factor receptor tyrosine kinases.
Huaibin Chen, William M Marsiglia, Min-Kyu Cho, Zhifeng Huang, Jingjing Deng, Nathaniel J Traaseth

Elife· February 2017

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Protonation of a glutamate residue modulates the dynamics of the drug transporter EmrE.
Anindita Gayen, Maureen Leninger, Nathaniel J Traaseth

Nat Chem Biol· March 2016

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A Miniature Protein Stabilized by a Cation-π Interaction Network.
Timothy W Craven, Min-Kyu Cho, Nathaniel J Traaseth, Richard Bonneau, Kent Kirshenbaum

J Am Chem Soc· February 2016

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Two FGF Receptor Kinase Molecules Act in Concert to Recruit and Transphosphorylate Phospholipase Cγ.
Zhifeng Huang, William M Marsiglia, Upal Basu Roy, Nader Rahimi, Dariush Ilghari, Nathaniel J Traaseth

Mol Cell· January 2016

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