Publications by authors named "Nazem Atassi"

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Characterizing Treatment Patterns and Healthcare Use in Patients and Subgroups with Chronic Inflammatory Demyelinating Polyradiculoneuropathy: A Real-World Study.
Hans-Peter Hartung, Nazem Atassi, Miguel Alonso-Alonso, Manuel Nunez, Alex Seluzhytsky

Neurol Ther· November 2025

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Safety, pharmacokinetics, and target engagement of a brain penetrant RIPK1 inhibitor, SAR443820 (DNL788), in healthy adult participants.
Agnes Hincelin-Mery, Xavier Nicolas, Cathy Cantalloube, Robert Pomponio, Pascale Lewanczyk, Nazem Atassi

Clin Transl Sci· January 2024

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An innovative phase 2 proof-of-concept trial design to evaluate SAR445088, a monoclonal antibody targeting complement C1s in chronic inflammatory demyelinating polyneuropathy.
Luis Querol, Richard A Lewis, Hans-Peter Hartung, Pieter A Van Doorn, Erik Wallstroem, Nazem Atassi

J Peripher Nerv Syst· June 2023

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Selective atrophy of the cervical enlargement in whole spinal cord MRI of amyotrophic lateral sclerosis.
Robert L Barry, Angel Torrado-Carvajal, John E Kirsch, Grae E Arabasz, Daniel S Albrecht, Nazem Atassi

Neuroimage Clin· December 2022

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Safety, pharmacokinetics and target engagement of novel RIPK1 inhibitor SAR443060 (DNL747) for neurodegenerative disorders: Randomized, placebo-controlled, double-blind phase I/Ib studies in healthy subjects and patients.
Maurits F J M Vissers, Jules A A C Heuberger, Geert Jan Groeneveld, Jerome Oude Nijhuis, Peter Paul De Deyn, Nazem Atassi

Clin Transl Sci· August 2022

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Classical Complement Pathway Inhibition in a "Human-On-A-Chip" Model of Autoimmune Demyelinating Neuropathies.
John W Rumsey, Case Lorance, Max Jackson, Trevor Sasserath, Christopher W McAleer, Nazem Atassi

Adv Ther (Weinh)· June 2022

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The Role of the Complement System in Chronic Inflammatory Demyelinating Polyneuropathy: Implications for Complement-Targeted Therapies.
Luis A Querol, Hans-Peter Hartung, Richard A Lewis, Pieter A van Doorn, Timothy R Hammond, Nazem Atassi

Neurotherapeutics· April 2022

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Tocilizumab is safe and tolerable and reduces C-reactive protein concentrations in the plasma and cerebrospinal fluid of ALS patients.
Carol Milligan, Nazem Atassi, Suma Babu, Richard J Barohn, James B Caress

Muscle Nerve· September 2021

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Ultra-high field (7T) functional magnetic resonance imaging in amyotrophic lateral sclerosis: a pilot study.
Robert L Barry, Suma Babu, Sheeba Arnold Anteraper, Christina Triantafyllou, Boris Keil, Nazem Atassi

Neuroimage Clin· July 2021

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Ibudilast (MN-166) in amyotrophic lateral sclerosis- an open label, safety and pharmacodynamic trial.
Suma Babu, Baileigh G Hightower, James Chan, Nicole R Zürcher, Pia Kivisäkk, Nazem Atassi

Neuroimage Clin· July 2021

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Effects of mexiletine on hyperexcitability in sporadic amyotrophic lateral sclerosis: Preliminary findings from a small phase II randomized controlled trial.
Michael D Weiss, Eric A Macklin, Courtney E McIlduff, Steve Vucic, Brian J Wainger, Nazem Atassi

Muscle Nerve· March 2021

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Comparison of Two Clinical Upper Motor Neuron Burden Rating Scales in ALS Using Quantitative Brain Imaging.
Meena M Makary, Akila Weerasekara, Haley Rodham, Baileigh G Hightower, Chieh-En J Tseng, Nazem Atassi

ACS Chem Neurosci· March 2021

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Effect of Ezogabine on Cortical and Spinal Motor Neuron Excitability in Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial.
Brian J Wainger, Eric A Macklin, Steve Vucic, Courtney E McIlduff, Sabrina Paganoni, Nazem Atassi

JAMA Neurol· February 2021

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Moving Toward Multicenter Therapeutic Trials in Amyotrophic Lateral Sclerosis: Feasibility of Data Pooling Using Different Translocator Protein PET Radioligands.
Donatienne Van Weehaeghe, Suma Babu, Joke De Vocht, Nicole R Zürcher, Sheena Chew, Nazem Atassi

J Nucl Med· November 2020

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The NEALS primary lateral sclerosis registry.
Sabrina Paganoni, Fabiola De Marchi, James Chan, Sara K Thrower, Nathan P Staff, Nazem Atassi

Amyotroph Lateral Scler Frontotemporal Degener· November 2020

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Phase 1-2 Trial of Antisense Oligonucleotide Tofersen for ALS.
Timothy Miller, Merit Cudkowicz, Pamela J Shaw, Peter M Andersen, Nazem Atassi

N Engl J Med· July 2020

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Selection design phase II trial of high dosages of tamoxifen and creatine in amyotrophic lateral sclerosis.
Suma Babu, Eric A Macklin, Katherine E Jackson, Elizabeth Simpson, Katy Mahoney, Nazem Atassi

Amyotroph Lateral Scler Frontotemporal Degener· February 2020

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Multi-Modal Signatures of Tau Pathology, Neuronal Fiber Integrity, and Functional Connectivity in Traumatic Brain Injury.
Dustin W Wooten, Laura Ortiz-Terán, Nevena Zubcevik, Xiaomeng Zhang, Chuan Huang, Nazem Atassi

J Neurotrauma· December 2019

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ALS/SURV: a modification of the CAFS statistic.
Stephen A Goutman, Morton B Brown, Merit Cudkowicz, Nazem Atassi, Eva L Feldman

Amyotroph Lateral Scler Frontotemporal Degener· November 2019

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Class I and II histone deacetylase expression is not altered in human amyotrophic lateral sclerosis: Neuropathological and positron emission tomography molecular neuroimaging evidence.
Amanda M Dios, Suma Babu, Eric J Granucci, Kaly A Mueller, Alexandra N Mills, Nazem Atassi

Muscle Nerve· October 2019

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Design and analysis of a clinical trial using previous trials as historical control.
David Alan Schoenfeld, Dianne M Finkelstein, Eric Macklin, Neta Zach, David L Ennist, Nazem Atassi

Clin Trials· October 2019

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Prospective natural history study of ALS clinical characteristics and biomarkers.
Alexander J Cammack, Nazem Atassi, Theodore Hyman, Leonard H van den Berg, Matthew Harms

Neurology· October 2019

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Adjusted cost analysis of video televisits for the care of people with amyotrophic lateral sclerosis.
Sabrina Paganoni, Marc van de Rijn, Kristin Drake, Katherine Burke, Michael Doyle, Nazem Atassi

Muscle Nerve· August 2019

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Positron Emission Tomography Molecular Imaging Biomarkers for Amyotrophic Lateral Sclerosis.
Sheena Chew, Nazem Atassi

Front Neurol· March 2019

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Stratification of amyotrophic lateral sclerosis patients: a crowdsourcing approach.
Robert Kueffner, Neta Zach, Maya Bronfeld, Raquel Norel, Nazem Atassi

Sci Rep· January 2019

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