Publications by authors named "Nazif Alic"

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Transcriptional memory of dFOXO activation in youth curtails later-life mortality through chromatin remodeling and Xbp1.
Guillermo Martínez Corrales, Mengjia Li, Tatiana Svermova, Alex Goncalves, Diana Voicu, Adam J Dobson, Tony D Southall, Nazif Alic

Nat Aging· December 2022

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Loss of Pol III repressor Maf1 in neurons promotes longevity by preventing the age-related decline in 5S rRNA and translation.
Bowen Xu, Alexander Hull, Olivia N M Hill, Naja Kobal, Enric Ureña, Nazif Alic

PLoS Biol· July 2025

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Ageing-associated long non-coding RNA extends lifespan and reduces translation in non-dividing cells.
Shajahan Anver, Ahmed Faisal Sumit, Xi-Ming Sun, Abubakar Hatimy, Konstantinos Thalassinos, Nazif Alic

EMBO Rep· November 2024

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Disruption of tRNA biogenesis enhances proteostatic resilience, improves later-life health, and promotes longevity.
Yasir Malik, Yavuz Kulaberoglu, Shajahan Anver, Sara Javidnia, Gillian Borland, Nazif Alic

PLoS Biol· October 2024

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Timing of TORC1 inhibition dictates Pol III involvement in longevity.
Yasir Malik, Isabel Goncalves Silva, Rene Rivera Diazgranados, Colin Selman, Nazif Alic

Life Sci Alliance· July 2024

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Xbp1 targets canonical UPR and non-canonical pathways in separate tissues to promote longevity.
Mengjia Li, Haocheng Shou, Guillermo Martínez Corrales, Tatiana Svermova, Alessandra Vieira Franco, Nazif Alic

iScience· June 2024

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Polr3b heterozygosity in mice induces both beneficial and deleterious effects on health during ageing with no effect on lifespan.
Gillian Borland, Stephen E Wilkie, Jackie Thomson, Zhe Wang, Jennifer M A Tullet, Nazif Alic

Aging Cell· May 2024

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Trametinib ameliorates aging-associated gut pathology in females by reducing Pol III activity in intestinal stem cells.
Enric Ureña, Bowen Xu, Jennifer C Regan, Magda L Atilano, Lucy J Minkley, Nazif Alic

Proc Natl Acad Sci U S A· January 2024

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Mendelian randomization analyses implicate biogenesis of translation machinery in human aging.
Sara Javidnia, Stephen Cranwell, Stefanie H Mueller, Colin Selman, Jennifer M A Tullet, Nazif Alic

Genome Res· February 2022

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Corrigendum: RNA Polymerase III, Ageing and Longevity.
Yavuz Kulaberoglu, Yasir Malik, Gillian Borland, Colin Selman, Nazif Alic

Front Genet· September 2021

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RNA Polymerase III, Ageing and Longevity.
Yavuz Kulaberoglu, Yasir Malik, Gillian Borland, Colin Selman, Nazif Alic

Front Genet· July 2021

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identification of genes encoding RNA polymerase subunits.
Steven J Marygold, Nazif Alic, David S Gilmour, Savraj S Grewal

MicroPubl Biol· October 2020

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The neuronal receptor tyrosine kinase Alk is a target for longevity.
Nathaniel S Woodling, Benjamin Aleyakpo, Miranda Claire Dyson, Lucy J Minkley, Arjunan Rajasingam, Nazif Alic

Aging Cell· May 2020

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Evolutionary Conservation of Transcription Factors Affecting Longevity.
Guillermo Martínez Corrales, Nazif Alic

Trends Genet· May 2020

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Partial Inhibition of RNA Polymerase I Promotes Animal Health and Longevity.
Guillermo Martínez Corrales, Danny Filer, Katharina C Wenz, Abbie Rogan, George Phillips, Nazif Alic

Cell Rep· February 2020

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Increased mitochondrial and lipid metabolism is a conserved effect of Insulin/PI3K pathway downregulation in adipose tissue.
Lucia Bettedi, Anqi Yan, Eugene Schuster, Nazif Alic, Lazaros C Foukas

Sci Rep· February 2020

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Longevity is determined by ETS transcription factors in multiple tissues and diverse species.
Adam J Dobson, Richard Boulton-McDonald, Lara Houchou, Tatiana Svermova, Ziyu Ren, Nazif Alic

PLoS Genet· July 2019

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RNA polymerase III limits longevity downstream of TORC1.
Danny Filer, Maximillian A Thompson, Vakil Takhaveev, Adam J Dobson, Ilektra Kotronaki, Nazif Alic

Nature· December 2017

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Sexually dimorphic effects of dietary sugar on lifespan, feeding and starvation resistance in .
Bhakti Chandegra, Jocelyn Lok Yee Tang, Haoyu Chi, Nazif Alic

Aging (Albany NY)· December 2017

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Intestinal Fork Head Regulates Nutrient Absorption and Promotes Longevity.
Ekin Bolukbasi, Mobina Khericha, Jennifer C Regan, Dobril K Ivanov, Jennifer Adcott, Nazif Alic

Cell Rep· October 2017

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A proteomic atlas of insulin signalling reveals tissue-specific mechanisms of longevity assurance.
Luke S Tain, Robert Sehlke, Chirag Jain, Manopriya Chokkalingam, Nagarjuna Nagaraj, Nazif Alic

Mol Syst Biol· September 2017

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Nutritional Programming of Lifespan by FOXO Inhibition on Sugar-Rich Diets.
Adam J Dobson, Marina Ezcurra, Charlotte E Flanagan, Adam C Summerfield, Matthew D W Piper, Nazif Alic

Cell Rep· January 2017

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Of FOXes and Forgetful Worms.
Nazif Alic

Cell Metab· March 2016

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Deletion of endogenous Tau proteins is not detrimental in Drosophila.
Sylvie Burnouf, Sebastian Grönke, Hrvoje Augustin, Jacqueline Dols, Marianna Karina Gorsky, Nazif Alic

Sci Rep· March 2016

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Nuclear hormone receptor DHR96 mediates the resistance to xenobiotics but not the increased lifespan of insulin-mutant Drosophila.
Sonita Afschar, Janne M Toivonen, Julia Marianne Hoffmann, Luke Stephen Tain, Daniela Wieser, Nazif Alic

Proc Natl Acad Sci U S A· February 2016

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