Publications by authors named "Ned Heindel"

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Optimizing Nanosuspension Drug Release and Wound Healing Using a Design of Experiments Approach: Improving the Drug Delivery Potential of NDH-4338 for Treating Chemical Burns.
Tomas L Roldan, Shike Li, Christophe Guillon, Ned D Heindel, Jeffrey D Laskin

Pharmaceutics· March 2024

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Derivatives of 1,2,4-triazole imines acting as dual iNOS and tumor cell growth inhibitors.
Christophe Guillon, Anna M Vetrano, Jaya Saxena, Angela Hunter, Geraldine Verderone, Ned D Heindel

Bioorg Chem· October 2020

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Antioxidant/stress response in mouse epidermis following exposure to nitrogen mustard.
Gabriella Wahler, Diane E Heck, Ned D Heindel, Debra L Laskin, Jeffrey D Laskin

Exp Mol Pathol· June 2020

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Phototoxicity of 7-oxycoumarins with keratinocytes in culture.
Christophe Guillon, Yi-Hua Jan, Diane E Heck, Thomas M Mariano, Robert D Rapp, Ned D Heindel

Bioorg Chem· August 2019

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Synthetically modified methoxsalen for enhanced cytotoxicity in light and dark reactions.
Christophe D Guillon, Yi-Hua Jan, Natalie Foster, Joel Ressner, Diane E Heck, Ned D Heindel

Bioorg Med Chem Lett· February 2019

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Sulfur mustard induced mast cell degranulation in mouse skin is inhibited by a novel anti-inflammatory and anticholinergic bifunctional prodrug.
Laurie B Joseph, Gabriella M Composto, Roberto M Perez, Hong-Duck Kim, Robert P Casillas, Ned D Heindel

Toxicol Lett· September 2018

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Identification of a Pyranocoumarin Photosensitizer that is a Potent Inhibitor of Keratinocyte Growth.
Jeffrey D Laskin, Yi-Hua Jan, Michele M Jetter, Christophe D Guillon, Thomas M Mariano, Ned D Heindel

Photochem Photobiol· May 2018

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SYNTHESIS AND EVALUATION OF WATER-SOLUBLE DIMETHYLAMINOETHYL ETHERS OF METHOXSALEN FOR PROLIFERATIVE SKIN DISORDERS.
Christophe D Guillon, Yi-Hua Jan, Natalie Foster, Mridula Choudhuri, Jaya Saxena, Ned D Heindel

Heterocycl Lett· January 2018

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Multi-inhibitor prodrug constructs for simultaneous delivery of anti-inflammatory agents to mustard-induced skin injury.
Carl J Lacey, Irene Wohlman, Christophe Guillon, Jaya Saxena, Cynthia Fianu-Velgus, Ned D Heindel

Ann N Y Acad Sci· August 2016

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Mustard vesicants alter expression of the endocannabinoid system in mouse skin.
Irene M Wohlman, Gabriella M Composto, Diane E Heck, Ned D Heindel, C Jeffrey Lacey

Toxicol Appl Pharmacol· July 2016

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Mitigation of nitrogen mustard mediated skin injury by a novel indomethacin bifunctional prodrug.
Gabriella M Composto, Jeffrey D Laskin, Debra L Laskin, Donald R Gerecke, Robert P Casillas, Ned D Heindel

Exp Mol Pathol· June 2016

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Selective Targeting of Heme Protein in Cytochrome P450 and Nitric Oxide Synthase by Diphenyleneiodonium.
John T Szilagyi, Vladimir Mishin, Diane E Heck, Yi-Hua Jan, Lauren M Aleksunes, Ned D Heindel

Toxicol Sci· May 2016

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ADAM17 Inhibitors Attenuate Corneal Epithelial Detachment Induced by Mustard Exposure.
Andrea DeSantis-Rodrigues, Yoke-Chen Chang, Rita A Hahn, Iris P Po, Peihong Zhou, Ned D Heindel

Invest Ophthalmol Vis Sci· April 2016

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Ethynylphenyl carbonates and carbamates as dual-action acetylcholinesterase inhibitors and anti-inflammatory agents.
Jaya Saxena, David Meloni, Mou-Tuan Huang, Diane E Heck, Jeffrey D Laskin, Ned D Heindel

Bioorg Med Chem Lett· December 2015

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Sulfa drugs inhibit sepiapterin reduction and chemical redox cycling by sepiapterin reductase.
Shaojun Yang, Yi-Hua Jan, Vladimir Mishin, Jason R Richardson, Muhammad M Hossain, Ned D Heindel

J Pharmacol Exp Ther· March 2015

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Therapeutic potential of a non-steroidal bifunctional anti-inflammatory and anti-cholinergic agent against skin injury induced by sulfur mustard.
Yoke-Chen Chang, James D Wang, Rita A Hahn, Marion K Gordon, Laurie B Joseph, Ned D Heindel

Toxicol Appl Pharmacol· October 2014

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-NITRO--SUBSTITUTED GUANIDINES: A SIMPLE CLASS OF NITRIC OXIDE SYNTHASE INHIBITORS.
Christophe D Guillon, David D Wisnoski, Jaya Saxena, Ned D Heindel, Diane E Heck

Mod Res Inflamm· May 2014

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Pharmacokinetics and metabolism of SRX246: a potent and selective vasopressin 1a antagonist.
Karine M Fabio, Christophe D Guillon, Shi-Fang Lu, Ned D Heindel, Michael J Brownstein

J Pharm Sci· June 2013

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Back-scattering interferometry: an ultrasensitive method for the unperturbed detection of acetylcholinesterase-inhibitor interactions.
Gabrielle L Haddad, Sherri C Young, Ned D Heindel, Darryl J Bornhop, Robert A Flowers

Angew Chem Int Ed Engl· October 2012

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Investigation of anticholinergic and non-steroidal anti-inflammatory prodrugs which reduce chemically induced skin inflammation.
Sherri C Young, Karine M Fabio, Mou-Tuan Huang, Jaya Saxena, Meredith P Harman, Ned D Heindel

J Appl Toxicol· February 2012

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Synthesis and evaluation of potent and selective human V1a receptor antagonists as potential ligands for PET or SPECT imaging.
Karine Fabio, Christophe Guillon, Carl J Lacey, Shi-fang Lu, Ned D Heindel

Bioorg Med Chem· February 2012

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Doxycycline hydrogels as a potential therapy for ocular vesicant injury.
Marion K Gordon, Andrea Desantis, Manjeet Deshmukh, Carl Jeffrey Lacey, Rita A Hahn, Ned D Heindel

J Ocul Pharmacol Ther· October 2010

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Oxidants and antioxidants in sulfur mustard-induced injury.
Jeffrey D Laskin, Adrienne T Black, Yi-Hua Jan, Patrick J Sinko, Ned D Heindel

Ann N Y Acad Sci· August 2010

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Peripheral site acetylcholinesterase inhibitors targeting both inflammation and cholinergic dysfunction.
Sherri Young, Karine Fabio, Christophe Guillon, Pramod Mohanta, Timothy A Halton, Ned D Heindel

Bioorg Med Chem Lett· May 2010

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Mechanisms mediating the vesicant actions of sulfur mustard after cutaneous exposure.
Michael P Shakarjian, Diane E Heck, Joshua P Gray, Patrick J Sinko, Marion K Gordon, Ned D Heindel

Toxicol Sci· March 2010

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