Publications by authors named "Neetu Dayal"

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3H-pyrazolo[4,3-f]quinoline hinge binder, a tunable scaffold for development of novel kinase inhibitors against FLT3-driven leukemia.
Neetu Dayal, Eva Řezníčková, Delmis E Hernandez, Miroslav Peřina, Jakub Bělíček

Eur J Med Chem· January 2026

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Identification of alkynyl nicotinamide HSN748 as a RET solvent-front mutant inhibitor with intracranial efficacy.
Ujjwol Khatri, Neetu Dayal, Kofi B Owusu, Mandeep Kaur Hunjan, Shriya Pandey

RSC Med Chem· August 2025

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Morpholino nicotinamide analogs of ponatinib, dual MNK, p70S6K inhibitors, display efficacy against lung and breast cancers.
Riddhi Chaudhuri, Neetu Dayal, Joshua Kaiser, Rodrigo Mohallem, Nickolas R Brauer

Bioorg Chem· June 2025

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Boronic Acid-Containing 3- pyrazolo[4,3-]quinoline Compounds as Dual CLK/ROCK Inhibitors with Anticancer Properties.
Neetu Dayal, Riddhi Chaudhuri, Kofi Simpa Yeboah, Nickolas R Brauer, Herman O Sintim

Pharmaceuticals (Basel)· December 2024

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Alkynyl nicotinamides show antileukemic activity in drug-resistant acute myeloid leukemia.
Baskar Ramdas, Neetu Dayal, Ruchi Pandey, Elizabeth Larocque, Rahul Kanumuri

J Clin Invest· June 2024

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Identification and characterization of a potent and selective HUNK inhibitor for treatment of HER2+ breast cancer.
Tinslee Dilday, Melissa Abt, Nicole Ramos-Solís, Neetu Dayal, Elizabeth Larocque

Cell Chem Biol· May 2024

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Identification of a Selective FLT3 Inhibitor with Low Activity against VEGFR, FGFR, PDGFR, c-KIT, and RET Anti-Targets.
Desmond Akwata, Allison L Kempen, Neetu Dayal, Nickolas R Brauer, Herman O Sintim

ChemMedChem· January 2024

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Discovery of imidazo[1,2-]pyridazine-containing TAK1 kinase inhibitors with excellent activities against multiple myeloma.
Desmond Akwata, Allison L Kempen, Jones Lamptey, Neetu Dayal, Nickolas R Brauer

RSC Med Chem· January 2024

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Targeting RET Solvent-Front Mutants with Alkynyl Nicotinamide-Based Inhibitors.
Ujjwol Khatri, Neetu Dayal, Xueqing Hu, Elizabeth Larocque, Nimishetti Naganna

Mol Cancer Ther· June 2023

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STING antagonists, synthesized Povarov-Doebner type multicomponent reaction.
Wilson W S Ong, Neetu Dayal, Riddhi Chaudhuri, Jones Lamptey, Herman O Sintim

RSC Med Chem· June 2023

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Re-sensitization of Multidrug-Resistant and Colistin-Resistant Gram-Negative Bacteria to Colistin by Povarov/Doebner-Derived Compounds.
Kenneth I Onyedibe, Ansley M Nemeth, Neetu Dayal, Richard D Smith, Jones Lamptey

ACS Infect Dis· February 2023

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Membrane acting Povarov-Doebner derived compounds potently disperse preformed multidrug resistant Gram-positive bacterial biofilms.
Neetu Dayal, Kenneth I Onyedibe, Whitney M Gribble, Herman O Sintim

Eur J Med Chem· October 2022

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Isoquinoline Antimicrobial Agent: Activity against Intracellular Bacteria and Effect on Global Bacterial Proteome.
Caroline W Karanja, Nimishetti Naganna, Nader S Abutaleb, Neetu Dayal, Kenneth I Onyedibe

Molecules· August 2022

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SF- and SCF-substituted tetrahydroquinoline compounds as potent bactericidal agents against multidrug-resistant persister Gram-positive bacteria.
Kenneth I Onyedibe, Neetu Dayal, Herman O Sintim

RSC Med Chem· November 2021

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3-Pyrazolo[4,3-]quinoline-Based Kinase Inhibitors Inhibit the Proliferation of Acute Myeloid Leukemia Cells In Vivo.
Neetu Dayal, Eva Řezníčková, Delmis E Hernandez, Miroslav Peřina, Sandra Torregrosa-Allen

J Med Chem· August 2021

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HSD1787, a Tetrahydro-3-Pyrazolo[4,3-]Quinoline Compound Synthesized via Povarov Reaction, Potently Inhibits Proliferation of Cancer Cell Lines at Nanomolar Concentrations.
Neetu Dayal, Modi Wang, Herman O Sintim

ACS Omega· September 2020

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Inhibitors of Intracellular Gram-Positive Bacterial Growth Synthesized via Povarov-Doebner Reactions.
Neetu Dayal, Clement Opoku-Temeng, Haroon Mohammad, Nader S Abutaleb, Delmis Hernandez

ACS Infect Dis· November 2019

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Potently inhibiting cancer cell migration with novel 3H-pyrazolo[4,3-f]quinoline boronic acid ROCK inhibitors.
Neetu Dayal, Clinton G Mikek, Delmis Hernandez, George A Naclerio, Elizabeth Fei Yin Chu

Eur J Med Chem· October 2019

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Berenil Binds Tightly to Parallel and Mixed Parallel/Antiparallel G-Quadruplex Motifs with Varied Thermodynamic Signatures.
Clinton G Mikek, Savannah J West, J Cole Gwin, Neetu Dayal, Herman O Sintim

ACS Omega· September 2018

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3H-pyrazolo[4,3-f]quinoline haspin kinase inhibitors and anticancer properties.
Clement Opoku-Temeng, Neetu Dayal, Moloud Aflaki Sooreshjani, Herman O Sintim

Bioorg Chem· August 2018

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N-(1,3,4-oxadiazol-2-yl)benzamide analogs, bacteriostatic agents against methicillin- and vancomycin-resistant bacteria.
Clement Opoku-Temeng, George A Naclerio, Haroon Mohammad, Neetu Dayal, Nader S Abutaleb

Eur J Med Chem· July 2018

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Tetrahydro-3H-pyrazolo[4,3-a]phenanthridine-based CDK inhibitor.
Clement Opoku-Temeng, Neetu Dayal, Delmis E Hernandez, N Naganna, Herman O Sintim

Chem Commun (Camb)· May 2018

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Dual FLT3/TOPK inhibitor with activity against FLT3-ITD secondary mutations potently inhibits acute myeloid leukemia cell lines.
Neetu Dayal, Clement Opoku-Temeng, Delmis E Hernandez, Moloud Aflaki Sooreshjani, Brandon A Carter-Cooper

Future Med Chem· April 2018

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Formation of amides, their intramolecular reactions for the synthesis of N-heterocycles, and preparation of a marketed drug, sildenafil: a comprehensive coverage.
Joydev K Laha, Ketul V Patel, K S Satyanarayana Tummalapalli, Neetu Dayal

Chem Commun (Camb)· August 2016

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Palladium-catalyzed regioselective C-2 arylation of 7-azaindoles, indoles, and pyrroles with arenes.
Joydev K Laha, Rohan A Bhimpuria, Dilip V Prajapati, Neetu Dayal, Shubhra Sharma

Chem Commun (Camb)· March 2016

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