Publications by authors named "Neil Alexis"

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Human Sputum Microbiome Composition and Sputum Inflammatory Cell Profiles Are Altered with Controlled Wood Smoke Exposure as a Model for Wildfire Smoke.
Catalina Cobos-Uribe, Radhika Dhingra, Martha A Almond, Neil E Alexis, David B Peden

Am J Respir Crit Care Med· November 2025

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Exploratory analysis of the impact of sex on sputum proteomic response to inhaled wood smoke in humans.
Morgan Nalesnik, Elise Hickman, Martha Almond, Laura Herring, Angie L Mordant, Alexis Payton, Neil E Alexis

Toxicol Sci· October 2025

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Associations of serum and bronchoalveolar immunoglobulins with lung microbiota diversity, B-cell memory phenotypes, and COPD morbidity and exacerbations.
Vickram Tejwani, Nirupama Putcha, Han Woo, Chen Liu, David Lafon, Neil E Alexis

Respir Res· July 2025

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Respiratory extracellular vesicle isolation optimization through proteomic profiling of equine samples and identification of candidates for cell-of-origin studies.
Elise Hickman, Victoria Carberry, Celeste Carberry, Bethanie Cooper, Angie L Mordant, Neil E Alexis

PLoS One· May 2025

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Cough-Variant Asthma: The Asthma Phenotype No One Coughs About.
Elizabeth Corteselli, Neil Alexis

Am J Respir Cell Mol Biol· March 2025

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Effect of prednisone on woodsmoke-induced sputum inflammation in healthy volunteers: A randomized, placebo-controlled pilot study.
Terry L Noah, Neil E Alexis, William D Bennett, Michelle L Hernandez, Allison J Burbank

J Allergy Clin Immunol Glob· February 2025

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Development and qualification of an LC-MS/MS method for quantification of MUC5AC and MUC5B mucins in spontaneous sputum.
Weiwen Sun, Si Mou, Catherine Huntington, Helen Killick, Ian Christopher Scott, Neil E Alexis

Bioanalysis· February 2025

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Design of the SPIROMICS Study of Early COPD Progression: SOURCE Study.
Jeffrey L Curtis, Lori A Bateman, Susan Murray, David J Couper, Wassim W Labaki, Neil E Alexis

Chronic Obstr Pulm Dis· September 2024

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Loss of Airway Phylogenetic Diversity Is Associated with Clinical and Pathobiological Markers of Disease Development in Chronic Obstructive Pulmonary Disease.
Kristopher Opron, Lesa A Begley, John R Erb-Downward, Gen Li, Neil E Alexis

Am J Respir Crit Care Med· July 2024

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Application of artificial intelligence in quantifying lung deposition dose of black carbon in people with exposure to ambient combustion particles.
Menghui Jiang, Chelin Jamie Hu, Cassie L Rowe, Huining Kang, Xi Gong, Neil E Alexis

J Expo Sci Environ Epidemiol· May 2024

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Airway Proteotypes of E-Cigarette Users Overlap with Those Found in Asthmatics.
Elise Hickman, Neil E Alexis, Julia E Rager, Ilona Jaspers

Am J Respir Cell Mol Biol· April 2024

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Proximal and Distal Bronchioles Contribute to the Pathogenesis of Non-Cystic Fibrosis Bronchiectasis.
Takanori Asakura, Kenichi Okuda, Gang Chen, Hong Dang, Takafumi Kato, Neil E Alexis

Am J Respir Crit Care Med· February 2024

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Eosinophils-from cradle to grave: An EAACI task force paper on new molecular insights and clinical functions of eosinophils and the clinical effects of targeted eosinophil depletion.
Milos Jesenak, Zuzana Diamant, Dagmar Simon, Ellen Tufvesson, Sven F Seys, Neil E Alexis

Allergy· December 2023

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Indoor Pollution and Lung Function Decline in Current and Former Smokers: SPIROMICS AIR.
Nadia N Hansel, Han Woo, Kirsten Koehler, Amanda Gassett, Laura M Paulin, Neil E Alexis

Am J Respir Crit Care Med· November 2023

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A pilot randomized clinical trial of γ-tocopherol supplementation on wood smoke-induced neutrophilic and eosinophilic airway inflammation.
David B Peden, Martha Almond, Christian Brooks, Carole Robinette, Heather Wells, Neil Alexis

J Allergy Clin Immunol Glob· November 2023

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Vaping-Induced Proteolysis Causes Airway Surface Dehydration.
Arunava Ghosh, Raymond D Coakley, Neil E Alexis, Robert Tarran

Int J Mol Sci· October 2023

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Air Pollution and Diet: Potential Interacting Exposures in Asthma.
Emily Brigham, Alisa Hashimoto, Neil E Alexis

Curr Allergy Asthma Rep· September 2023

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Potential mechanisms mediating PM-induced alterations of H3N2 influenza virus infection and cytokine production in human bronchial epithelial cells.
Yinbiao Wang, Rui Zhang, Fuyun Yang, Lin Yang, Qingmei Li, Neil E Alexis

Ecotoxicol Environ Saf· July 2023

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Plasma sterols and vitamin D are correlates and predictors of ozone-induced inflammation in the lung: A pilot study.
Alexia N Perryman, Hye-Young H Kim, Alexis Payton, Julia E Rager, Erin E McNell, Neil E Alexis

PLoS One· May 2023

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A blood and bronchoalveolar lavage protein signature of rapid FEV decline in smoking-associated COPD.
Katarina M DiLillo, Katy C Norman, Christine M Freeman, Stephanie A Christenson, Neil E Alexis

Sci Rep· May 2023

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Airway and Systemic Prostaglandin E2 Association with COPD Symptoms and Macrophage Phenotype.
Vickram Tejwani, Andres F Villabona-Rueda, Pratik Khare, Cissy Zhang, Anne Le, Neil E Alexis

Chronic Obstr Pulm Dis· April 2023

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Clinical Implications of Low Absolute Blood Eosinophil Count in the SPIROMICS COPD Cohort.
W Blake LeMaster, P Miguel Quibrera, David Couper, Donald P Tashkin, Eugene R Bleecker, Neil E Alexis

Chest· March 2023

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Expanded characterization of in vitro polarized M0, M1, and M2 human monocyte-derived macrophages: Bioenergetic and secreted mediator profiles.
Elise Hickman, Timothy Smyth, Catalina Cobos-Uribe, Robert Immormino, Meghan E Rebuli, Neil E Alexis

PLoS One· March 2023

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Prolonged, physiologically relevant nicotine concentrations in the airways of smokers.
Charles R Esther, Wanda K O'Neal, Neil E Alexis, Abigail L Koch, Christopher B Cooper

Am J Physiol Lung Cell Mol Physiol· January 2023

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Black carbon content in airway macrophages is associated with increased severe exacerbations and worse COPD morbidity in SPIROMICS.
Vickram Tejwani, Han Woo, Chen Liu, Anna K Tillery, Amanda J Gassett, Neil E Alexis

Respir Res· November 2022

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