Publications by authors named "Neil Frankish"

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Bioactive Indanes: Design, synthesis and bioactivity investigation of 2,2-substituted Indane derivatives, a new bioactive Indane scaffold.
Tao Zhang, Kit Chan, Abdulilah Ece, Robin Daly, Aoife Cannon, Neil Frankish

Bioorg Chem· June 2025

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Design, synthesis and biological evaluation of a novel bioactive indane scaffold 2-(diphenylmethylene)c-2,3-dihydro-1H-inden-1-one with potential anticancer activity.
Tao Zhang, Vilmar Bandero, Claire Corcoran, Ismael Obaidi, Manuel Ruether, Neil Frankish

Eur J Pharm Sci· September 2023

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Bioactive indanes: insight into the bioactivity of indane dimers related to the lead anti-inflammatory molecule PH46A.
Kit Chan, Neil Frankish, Tao Zhang, Abdulilah Ece, Aoife Cannon

J Pharm Pharmacol· July 2020

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Bioactive indanes: Development and validation of an LC-MS/MS bioanalytical method for the determination of PH46A, a new potential anti-inflammatory agent, in dog and rat plasma and its application to a pharmacokinetic study in dog.
Gaia A Scalabrino, Tao Zhang, Neil Frankish, Helen Sheridan

J Pharm Biomed Anal· February 2020

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Bioactive Indanes: Proof of Concept Study for Enantioselective Synthetic Routes to PH46A, a New Potential Anti-Inflammatory Agent.
Tao Zhang, Gaia Scalabrino, Neil Frankish, Helen Sheridan

Molecules· June 2018

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The indane diastereoisomers, PH2 and PH5: divergence between their effects in delayed-type hypersensitivity models and a model of colitis.
Neil H Frankish, Brendan McHale, Helen Sheridan

J Pharm Pharmacol· January 2018

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Investigation of the Stereoselective Synthesis of the Indane Dimer PH46A, a New Potential Anti-inflammatory Agent.
Graham R Cumming, Tao Zhang, Gaia Scalabrino, Neil Frankish, Helen Sheridan

Org Process Res Dev· December 2017

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Antidiabetic Activities of an LC/MS Fingerprinted Aqueous Extract of Fagonia cretica L. in Preclinical Models.
Imran Nazir, Nisar Ur Rahman, Zunaira Alvi, M Hafizur Rahman, Jandirk Sendker, Neil Frankish

Planta Med· October 2017

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Erratum: Antidiabetic Activities of an LC/MS Fingerprinted Aqueous Extract of Fagonia cretica L. in Preclinical Models.
Imran Nazir, Nisar Ur Rahman, Zunaira Alvi, M Hafizur Rahman, Jandirk Sendker, Neil Frankish

Planta Med· October 2017

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Molecular structure studies of (1,2)-2-benzyl-2,3-dihydro-2-(1H-inden-2-yl)-1H-inden-1-ol.
Tao Zhang, Krzysztof Paluch, Gaia Scalabrino, Neil Frankish, Anne-Marie Healy

J Mol Struct· March 2015

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2-(Di-phenyl-methyl-idene)-2,3-di-hydro-1H-inden-1-one.
Tao Zhang, Vilmar Bandero, Tom McCabe, Neil Frankish, Helen Sheridan

Acta Crystallogr Sect E Struct Rep Online· October 2013

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(1S)-1-Phenylethanaminium 4-{[(1S,2S)-1-hydroxy-2,3-dihydro-1H,1'H-[2,2'-biinden]-2-yl]methyl}benzoate.
Christopher S Frampton, Tao Zhang, Gaia A Scalabrino, Neil Frankish, Helen Sheridan

Acta Crystallogr C· August 2012

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6-(methylamino)hexane-1,2,3,4,5-pentanol 4-(((1S,2S)-1-hydroxy-2,3-dihydro-1H,1'H-[2,2-biinden]-2-yl)methyl)benzoate (PH46A): a novel small molecule with efficacy in murine models of colitis.
Neil Frankish, Helen Sheridan

J Med Chem· June 2012

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N-Cyclo-pentyl-N-(3-oxo-2,3-dihydro-1H-inden-1-yl)acetamide.
Tao Zhang, Tom McCabe, Bartosz Marzec, Neil Frankish, Helen Sheridan

Acta Crystallogr Sect E Struct Rep Online· April 2012

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Enhancement of insulin release from the beta-cell line INS-1 by an ethanolic extract of Bauhinia variegata and its major constituent roseoside.
Neil Frankish, Fábio de Sousa Menezes, Clive Mills, Helen Sheridan

Planta Med· July 2010

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The RBL-2H3 cell line: its provenance and suitability as a model for the mast cell.
Egle Passante, Neil Frankish

Inflamm Res· November 2009

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Diastereoisomers of 2-benzyl-2, 3-dihydro-2-(1H-inden-2-yl)-1H-inden-1-ol: potential anti-inflammatory agents.
Helen Sheridan, John J Walsh, Carina Cogan, Michael Jordan, Tom McCabe, Neil H Frankish

Bioorg Med Chem Lett· October 2009

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RBL-2H3 cells are an imprecise model for mast cell mediator release.
Egle Passante, Carsten Ehrhardt, Helen Sheridan, Neil Frankish

Inflamm Res· September 2009

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Inhibition of LFA-1 mediated T-cell motility by naphthoquinones.
Helen Sheridan, Ingrid Hook, Cora Nestor, Jennifer Coppins, Carsten Ehrhardt, Neil Frankish

Planta Med· September 2008

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Investigation into the mast cell stabilizing activity of nature-identical and synthetic indanones.
Neil Frankish, Ronan Farrell, Helen Sheridan

J Pharm Pharmacol· November 2004

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Ionisation characteristics and elimination rates of some aminoindanones determined by capillary electrophoresis.
Ana Luísa Simplício, John F Gilmer, Neil Frankish, Helen Sheridan, John J Walsh

J Chromatogr A· August 2004

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