Publications by authors named "Neil S Forbes"

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Mathematical Modeling of Cancer Therapies Demonstrates the Necessity of Both Bacterial Cytotoxicity and Immune Activation.
Lars M Howell, Neil S Forbes

Bioengineering (Basel)· July 2025

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Controlling intracellular protein delivery, tumor colonization and tissue distribution using flhDC in clinically relevant ΔsseJ Salmonella.
Vishnu Raman, Christopher L Hall, Victoria E Wetherby, Samantha A Whitney, Nele Van Dessel, Neil S Forbes

Mol Ther· February 2025

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Intracellular delivery of oncolytic viruses with engineered Salmonella causes viral replication and cell death.
Shradha Khanduja, Shoshana M K Bloom, Vishnu Raman, Chinmay P Deshpande, Christopher L Hall, Neil S Forbes

iScience· June 2024

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Controlled production of lipopolysaccharides increases immune activation in Salmonella treatments of cancer.
Lars M Howell, Simin Manole, Alec R Reitter, Neil S Forbes

Microb Biotechnol· May 2024

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Intracellular delivery of an exogenous immunization antigen refocuses CD8 T cells against cancer cells, eliminates pancreatic tumors and forms antitumor immunity.
Vishnu Raman, Lars M Howell, Shoshana M K Bloom, Christopher L Hall, Victoria E Wetherby, Neil S Forbes

Front Immunol· November 2023

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Build-a-bug workshop: Using microbial-host interactions and synthetic biology tools to create cancer therapies.
Vishnu Raman, Chinmay P Deshpande, Shradha Khanduja, Lars M Howell, Nele Van Dessel, Neil S Forbes

Cell Host Microbe· October 2023

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Bacterial delivery of therapeutic proteins to the nuclei of cancer cells.
Shoshana M K Bloom, Nicholas O'Hare, Neil S Forbes

Biotechnol Bioeng· May 2023

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Bacteria-based immune therapies for cancer treatment.
Lars M Howell, Neil S Forbes

Semin Cancer Biol· November 2022

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Microbial Imbalance Induces Inflammation by Promoting Penetration through the Mucosal Barrier.
Abhinav Sharma, Vishnu Raman, Jungwoo Lee, Neil S Forbes

ACS Infect Dis· May 2022

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Intracellular delivery of protein drugs with an autonomously lysing bacterial system reduces tumor growth and metastases.
Vishnu Raman, Nele Van Dessel, Christopher L Hall, Victoria E Wetherby, Samantha A Whitney, Neil S Forbes

Nat Commun· October 2021

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Swimming back Toward Stiffer Polyetheylene Glycol Coatings, Increasing Contact in Flow.
Molly K Shave, Zhou Xu, Vishnu Raman, Surachate Kalasin, Mark T Tuominen, Neil S Forbes

ACS Appl Mater Interfaces· April 2021

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Mucus blocks probiotics but increases penetration of motile pathogens and induces TNF-α and IL-8 secretion.
Abhinav Sharma, Vishnu Raman, Jungwoo Lee, Neil S Forbes

Biotechnol Bioeng· August 2020

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In Vitro Reconstitution of an Intestinal Mucus Layer Shows That Cations and pH Control the Pore Structure That Regulates Its Permeability and Barrier Function.
Abhinav Sharma, Jun-Goo Kwak, Kristopher W Kolewe, Jessica D Schiffman, Neil S Forbes

ACS Appl Bio Mater· May 2020

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Detection of tumors with fluoromarker-releasing bacteria.
Jan T Panteli, Nele Van Dessel, Neil S Forbes

Int J Cancer· January 2020

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The motility regulator flhDC drives intracellular accumulation and tumor colonization of Salmonella.
Vishnu Raman, Nele Van Dessel, Owen M O'Connor, Neil S Forbes

J Immunother Cancer· February 2019

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White paper on microbial anti-cancer therapy and prevention.
Neil S Forbes, Robert S Coffin, Liang Deng, Laura Evgin, Steve Fiering

J Immunother Cancer· August 2018

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Tissue transport affects how treatment scheduling increases the efficacy of chemotherapeutic drugs.
Dan E Ganz, Briana Sexton-Stallone, Emily L Brackett, Neil S Forbes

J Theor Biol· February 2018

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Microfluidic Device to Quantify the Behavior of Therapeutic Bacteria in Three-Dimensional Tumor Tissue.
Emily L Brackett, Charles A Swofford, Neil S Forbes

Methods Mol Biol· November 2016

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Engineered bacteria detect spatial profiles in glucose concentration within solid tumor cell masses.
Jan T Panteli, Neil S Forbes

Biotechnol Bioeng· November 2016

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Persistent enhancement of bacterial motility increases tumor penetration.
Dana N Thornlow, Emily L Brackett, Jonathan M Gigas, Nele Van Dessel, Neil S Forbes

Biotechnol Bioeng· November 2015

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Genetically modified bacteria as a tool to detect microscopic solid tumor masses with triggered release of a recombinant biomarker.
Jan T Panteli, Brittany A Forkus, Nele Van Dessel, Neil S Forbes

Integr Biol (Camb)· April 2015

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Quorum-sensing Salmonella selectively trigger protein expression within tumors.
Charles A Swofford, Nele Van Dessel, Neil S Forbes

Proc Natl Acad Sci U S A· March 2015

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Potent and tumor specific: arming bacteria with therapeutic proteins.
Nele Van Dessel, Charles A Swofford, Neil S Forbes

Ther Deliv· March 2015

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Trg-deficient Salmonella colonize quiescent tumor regions by exclusively penetrating or proliferating.
Miaomin Zhang, Neil S Forbes

J Control Release· February 2015

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Bacterial delivery of Staphylococcus aureus α-hemolysin causes regression and necrosis in murine tumors.
Adam T St Jean, Charles A Swofford, Jan T Panteli, Zachary J Brentzel, Neil S Forbes

Mol Ther· July 2014

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