Publications by authors named "Neil Vargesson"

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Thalidomide-induced teratogenesis: history and mechanisms.
Neil Vargesson

Birth Defects Res C Embryo Today· June 2015

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Monoterpenoid fluorophthalimide IMiDs that lack human cereblon binding: synthesis and anti-proliferative, anti-angiogenic and anti-inflammatory activities.
Weiming Luo, Kathleen M Garchitorena, David Tweedie, Cindy H Chau, Chirag N Patel, Neil Vargesson

Biochem Biophys Res Commun· September 2025

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Cereblon E3 ligase complex genes are expressed in tissues sensitive to thalidomide in chicken and zebrafish embryos but are unchanged following thalidomide exposure.
Lucas Rosa Fraga, Jessica Reeves, Chris Mahony, Lynda Erskine, Neil Vargesson

Dev Biol· June 2025

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Targeting neuroinflammation: 3-monothiopomalidomide a new drug candidate to mitigate traumatic brain injury and neurodegeneration.
Shih Chang Hsueh, Pathik Parekh, Buyandelger Batsaikhan, Neil Vargesson, David Tweedie

J Biomed Sci· June 2025

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Identification of lens-regulated genes driving anterior eye development.
Verónica Murcia-Belmonte, Yanlin Liu, Sadia Shamsi, Sophie Shaw, Elaina Collie-Duguid, Neil Vargesson

Dev Biol· April 2025

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Embryonic Vascular Dysgenesis: The Origin of Proximal Femoral Focal Deficiency.
David R Hootnick, Neil Vargesson, Jason A Horton, Jiri Chomiak

Birth Defects Res· April 2025

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Emerging and novel technologies in reproductive and developmental toxicology.
Susan E Maier, Robert M Cabrera, Yichang Chen, Neil Vargesson

Reprod Toxicol· December 2024

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Assessment of the Teratogenic Effect of Drugs on the Chicken Embryo.
Lucas Rosa Fraga, Maikel Rosa de Oliveira, Karina Maria Wermann, Neil Vargesson

Methods Mol Biol· January 2024

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Teratogenicity and Reactive Oxygen Species after transient embryonic hypoxia: Experimental and clinical evidence with focus on drugs causing failed abortion in humans.
Bengt Danielsson, Neil Vargesson, Christian Danielsson

Reprod Toxicol· December 2023

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Functional filter for whole-genome sequencing data identifies HHT and stress-associated non-coding SMAD4 polyadenylation site variants >5 kb from coding DNA.
Sihao Xiao, Zhentian Kai, Daniel Murphy, Dongyang Li, Dilip Patel, Neil Vargesson

Am J Hum Genet· November 2023

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Considerations for future quantitative structure-activity relationship (QSAR) modelling for heavy metals - A case study of mercury.
Rebecca von Hellfeld, Christoph Gade, Neil Vargesson, Astley Hastings

Toxicology· November 2023

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Thalidomide upper limb embryopathy - pathogenesis, past and present management and future considerations.
Neil Vargesson, Geoffrey Hooper, Grey Giddins, Alastair Hunter, Paul Stirling

J Hand Surg Eur Vol· September 2023

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A New Generation of IMiDs as Treatments for Neuroinflammatory and Neurodegenerative Disorders.
Katherine O Kopp, Margaret E Greer, Elliot J Glotfelty, Shih-Chang Hsueh, David Tweedie, Neil Vargesson

Biomolecules· April 2023

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Novel, thalidomide-like, non-cereblon binding drug tetrafluorobornylphthalimide mitigates inflammation and brain injury.
Daniela Lecca, Shih-Chang Hsueh, Weiming Luo, David Tweedie, Dong Seok Kim, Neil Vargesson

J Biomed Sci· March 2023

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Thalidomide: history, withdrawal, renaissance, and safety concerns.
Neil Vargesson, Trent Stephens

Expert Opin Drug Saf· December 2021

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Knockdown of slit signaling during limb development leads to a reduction in humerus length.
Alexandra Rafipay, Xin-Peng Dun, David B Parkinson, Lynda Erskine, Neil Vargesson

Dev Dyn· September 2021

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From the Farm to the Lab: How Chicken Embryos Contribute to the Field of Teratology.
Gabriela Elis Wachholz, Bruna Duarte Rengel, Neil Vargesson, Lucas Rosa Fraga

Front Genet· July 2021

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Lewis Wolpert (1929-2021).
Neil Vargesson

Cells Dev· June 2021

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Genetic association and characterization of FSTL5 in isolated clubfoot.
Anas M Khanshour, Yared H Kidane, Julia Kozlitina, Reuel Cornelia, Alexandra Rafipay, Neil Vargesson

Hum Mol Genet· January 2021

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Antiangiogenic Activity and in Silico Cereblon Binding Analysis of Novel Thalidomide Analogs.
Megan L Peach, Shaunna L Beedie, Cindy H Chau, Matthew K Collins, Suzana Markolovic, Neil Vargesson

Molecules· December 2020

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Role of cereblon in angiogenesis and in mediating the antiangiogenic activity of immunomodulatory drugs.
Shaunna L Beedie, Phoebe A Huang, Emily M Harris, Jonathan D Strope, Christopher Mahony, Neil Vargesson

FASEB J· September 2020

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Positional Information-A concept underpinning our understanding of developmental biology.
Neil Vargesson

Dev Dyn· March 2020

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VGLL3 operates via TEAD1, TEAD3 and TEAD4 to influence myogenesis in skeletal muscle.
Nicolas Figeac, Abdalla D Mohamed, Congshan Sun, Martin Schönfelder, David Matallanas, Neil Vargesson

J Cell Sci· July 2019

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Vascular anomalies of the upper limb.
Konrad Mende, Neil Vargesson, Branavan Sivakumar

J Hand Surg Eur Vol· March 2019

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Limbal epithelial stem cell activity and corneal epithelial cell cycle parameters in adult and aging mice.
Nada Sagga, Lucia Kuffová, Neil Vargesson, Lynda Erskine, J Martin Collinson

Stem Cell Res· December 2018

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Analysis of the relationship between the KRAS G12V oncogene and the Hippo effector YAP1 in embryonal rhabdomyosarcoma.
Abdalla D Mohamed, Nupur Shah, Simone Hettmer, Neil Vargesson, Henning Wackerhage

Sci Rep· October 2018

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