Thalidomide became one of the world's largest selling drugs, & was marketed heavily and advertised as completely safe, just like the Covid vaccines. "Particularly suitable for children & the aged" "Free from untoward side-effects https://t.co/qHXpStWZP4 https://t.co/46Hn27XhH2
Thalidomide-induced teratogenesis: history and mechanisms.
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What people are saying
The discussions reflect a mix of concern over past harm, supported by comments on the history and mechanisms discussed in the article, and curiosity about current uses, as seen in mentions of DNA mutagenesis and regulatory changes. The tone is mostly attentive and analytical, emphasizing the importance of understanding thalidomide's impact and ongoing relevance.
Most discussions acknowledge the harmful history and mechanisms of thalidomide, showing general support for the importance of understanding its side effects.
Posts express high curiosity about the research, especially regarding recent discoveries and how the drug was marketed and remains in use today.
Several posts reference specific details like DNA mutagenesis and historical court cases, indicating active engagement with the article's content.
People recognize the significance of the publication in informing about drug safety and historical lessons, though some posts also mention its current medical uses.
Abstract in brief
- Thalidomide was first prescribed to treat morning sickness in pregnant women about 60 years ago, leading to a major disaster where over 10,000 children were born with severe birth defects.
- Although its original use caused harm, thalidomide is now used to treat certain adult conditions like multiple myeloma and leprosy complications, but recent cases in Brazil show new damage in children.
- Recent research has improved understanding of how thalidomide causes birth defects at the molecular level, though some challenges in fully understanding its mechanisms remain for scientists.
Top posts
Most liked on X and BlueskyGo watch my awesome friend @MsBeautyphile she has out a new video on "is sunscreen safe?". She is so great on the chemistry of the beauty industry. https://t.co/IzNM9qjYNv
Thalidomide-induced teratogenesis: history and mechanisms. - PubMed - NCBI https://t.co/Esg97G35jD
Thalidomide‐induced teratogenesis: History and mechanisms - Vargesson - 2015 - Birth Defects Research Part C: Embryo Today: Reviews - Wiley Online Library https://t.co/CoVyhndVPp
@N_Vargesson Good evening sir, I’m a Biology student from Texas and I just wanted to say that I loved your paper “Thalidomide-induced teratogenesis: History and mechanisms”. Have there been any recent discoveries about Thalidomide and Embryopathy? Thank you!
@Neoavatara @CincyNomad Thalidomide for morning sickness was an off-label use. https://t.co/JfAM2WJ5GG https://t.co/OPlyWuY1lr
All mentions
The Thalidomide Tragedy
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Thalidomide‐induced teratogenesis: History and mechanisms - Vargesson - 2015 - Birth Defects Research Part C: Embryo Today: Reviews - Wiley Online Library https://t.co/CoVyhndVPp
https://t.co/hbaTCKqMDu https://t.co/uccponLRAk
RT @mRNAdeaths: Thalidomide became one of the world's largest selling drugs, & was marketed heavily and advertised as completely safe, just…
RT @mRNAdeaths: Thalidomide became one of the world's largest selling drugs, & was marketed heavily and advertised as completely safe, just…
RT @mRNAdeaths: Thalidomide became one of the world's largest selling drugs, & was marketed heavily and advertised as completely safe, just…
RT @mRNAdeaths: Thalidomide became one of the world's largest selling drugs, & was marketed heavily and advertised as completely safe, just…
RT @mRNAdeaths: Thalidomide became one of the world's largest selling drugs, & was marketed heavily and advertised as completely safe, just…
RT @mRNAdeaths: Thalidomide became one of the world's largest selling drugs, & was marketed heavily and advertised as completely safe, just…
RT @mRNAdeaths: Thalidomide became one of the world's largest selling drugs, & was marketed heavily and advertised as completely safe, just…
RT @mRNAdeaths: Thalidomide became one of the world's largest selling drugs, & was marketed heavily and advertised as completely safe, just…
RT @mRNAdeaths: Thalidomide became one of the world's largest selling drugs, & was marketed heavily and advertised as completely safe, just…
RT @mRNAdeaths: Thalidomide became one of the world's largest selling drugs, & was marketed heavily and advertised as completely safe, just…
RT @mRNAdeaths: Thalidomide became one of the world's largest selling drugs, & was marketed heavily and advertised as completely safe, just…
RT @mRNAdeaths: Thalidomide became one of the world's largest selling drugs, & was marketed heavily and advertised as completely safe, just…
RT @mRNAdeaths: Thalidomide became one of the world's largest selling drugs, & was marketed heavily and advertised as completely safe, just…
RT @mRNAdeaths: Thalidomide became one of the world's largest selling drugs, & was marketed heavily and advertised as completely safe, just…
RT @mRNAdeaths: Thalidomide became one of the world's largest selling drugs, & was marketed heavily and advertised as completely safe, just…
RT @mRNAdeaths: Thalidomide became one of the world's largest selling drugs, & was marketed heavily and advertised as completely safe, just…
RT @mRNAdeaths: Thalidomide became one of the world's largest selling drugs, & was marketed heavily and advertised as completely safe, just…
RT @mRNAdeaths: Thalidomide became one of the world's largest selling drugs, & was marketed heavily and advertised as completely safe, just…
Thalidomide became one of the world's largest selling drugs, & was marketed heavily and advertised as completely safe, just like the Covid vaccines. "Particularly suitable for children & the aged" "Free from untoward side-effects https://t.co/qHXpStWZP4 https://t.co/46Hn27XhH2
@RefugeOfSinner5 B) People damaged by thalidomide (prescribed to treat morning sickness in pregnant women in the '60s caused DNA mutagenesis) can have perfectly formed babies. Thalidomide-induced teratogenesis: History and mechanisms https://t.co/703cv3qqoO
@HammersBagga @HelaRevenge @CKellyUAP Thalidomide-induced teratogenesis: History and mechanisms https://t.co/U8K5UwlQ50
@i11umin8ed @RyanMarino Thalidomide-induced teratogenesis: History and Mechanisms https://t.co/ey5bnJmOF2
Vargesson N. Thalidomide-induced teratogenesis: history and mechanisms. Birth Defects Res C Embryo Today. 2015 Jun;105(2):140-56. doi: 10.1002/bdrc.21096. Epub 2015 Jun 4. PMID: 26043938; PMCID: PMC4737249.
Hey, @TwitterSupport why is the link to this paper restricted? Thalidomide‐induced teratogenesis: History and mechanisms Neil Vargesson
@Neoavatara @CincyNomad Thalidomide for morning sickness was an off-label use. https://t.co/JfAM2WJ5GG https://t.co/OPlyWuY1lr
@GeorgeMo @liz_churchill8 @ManInAmericaUS https://t.co/FNFxeCBrI6
@Plainly_D https://t.co/44cT0dVdqy https://t.co/hSrjAvkWGu You need to read and to understand these. It's a beginning. Say 'when' and I will drop the other 34 refs I used for my postgrad.
Thalidomide-induced teratogenesis: History and mechanisms. Birth defects research. Part C, Embryo today: reviews, 105 (2), 140–156. https://t.co/lWZUdbWAei 3. Anorak. 1968 In Photos: The High Court Agrees to Meagre Compensation For Thalidomide Victims. 4. McBride, WG(1961).
@N_Vargesson Good evening sir, I’m a Biology student from Texas and I just wanted to say that I loved your paper “Thalidomide-induced teratogenesis: History and mechanisms”. Have there been any recent discoveries about Thalidomide and Embryopathy? Thank you!
Thalidomide‐induced teratogenesis: History and mechanisms https://t.co/76597yrTaL
Thalidomide‐induced teratogenesis: History and mechanisms https://t.co/VeoMy2MObV
@VergilioPica @aquinaband @padilhando @OsmarTerra @drivansartori @alexandregarcia https://t.co/igI35Z8I9f Sugiro ler esse artigo... Traz bem o resumo da história e explica os mecanismo que leva às malformações
Go watch my awesome friend @MsBeautyphile she has out a new video on "is sunscreen safe?". She is so great on the chemistry of the beauty industry. https://t.co/IzNM9qjYNv
msbeautyphile: Is sunscreen safe? (It's complicated) https://t.co/V2FK1BWjrq
RT @mrthalidomider: Thalidomide-induced teratogenesis: history and mechanisms. - PubMed - NCBI https://t.co/Esg97G35jD
RT @mrthalidomider: Thalidomide-induced teratogenesis: history and mechanisms. - PubMed - NCBI https://t.co/Esg97G35jD
RT @mrthalidomider: Thalidomide-induced teratogenesis: history and mechanisms. - PubMed - NCBI https://t.co/Esg97G35jD
Thalidomide-induced teratogenesis: history and mechanisms. - PubMed - NCBI https://t.co/Esg97G35jD
@mrthalidomider @_Chris_Magee_ @GMB Distinguished Federal Civil Service to FDA physician Dr. Frances Kelsey for averting a thalidomide disaster in the USA which is what led me to believe the US was not affected but perhaps there were just less cases? https://t.co/P1Aieh7WES
@Ness4612R @GMB Everything about its marketing was well shady. The thing about it only affecting niche species is a myth though. More here https://t.co/oMUJyM6Mnq . Also, did you know it's still used? Turns out to be a good treatment for cancer and leprosy.
RT @mrthalidomider: Thalidomide‐induced teratogenesis: History and mechanisms https://t.co/dHqYspA05y And you are so wrong thalidomide was…
Thalidomide‐induced teratogenesis: History and mechanisms https://t.co/dHqYspA05y And you are so wrong thalidomide was in USA from 1956 to 1962 as samples
Thalidomide‐induced teratogenesis: History and mechanisms https://t.co/dHqYspA05y